Search Results: Sphingomyelins

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Sphingomyelin
Kamis, 2026-06-04 02:15:22

phosphocholine and ceramide, or a phosphoethanolamine head group; therefore, sphingomyelins can also be classified as sphingophospholipids. In humans, SM represents...

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Sphingomyelin phosphodiesterase
Sabtu, 2025-10-04 04:48:32

Sphingomyelin phosphodiesterase (EC 3.1.4.12, also known as neutral sphingomyelinase, sphingomyelinase, or SMase; systematic name sphingomyelin cholinephosphohydrolase)...

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Sphingomyelin phosphodiesterase 1
Senin, 2025-08-25 14:32:29

Sphingomyelin phosphodiesterase 1 (SMPD1), also known as acid sphingomyelinase (ASM), is an enzyme that in humans is encoded by the SMPD1 gene. Sphingomyelin...

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Sphingomyelin phosphodiesterase D
Selasa, 2025-09-16 04:57:59

Sphingomyelin phosphodiesterase D (EC 3.1.4.41, sphingomyelinase D) is an enzyme of the sphingomyelin phosphodiesterase family with systematic name sphingomyelin...

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Lecithin–sphingomyelin ratio
Jumat, 2024-03-15 06:12:03

The lecithin–sphingomyelin ratio (L/S ratio or L-S ratio) is a test of fetal amniotic fluid to assess for fetal lung immaturity. Lungs require surfactant...

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Niemann–Pick disease
Jumat, 2025-12-05 09:47:32

varying severity. These are inherited metabolic disorders in which sphingomyelin accumulates in lysosomes in cells of many organs. NP types A, A/B, and...

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Lipid
Jumat, 2026-08-07 17:57:32

Glycerophospholipids, usually referred to as phospholipids (though sphingomyelins are also classified as phospholipids), are ubiquitous in nature and...

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Sphingomyelin synthase
Minggu, 2026-04-05 03:07:46

In enzymology, a sphingomyelin synthase (EC 2.7.8.27) is an enzyme that catalyzes the chemical reaction a ceramide + a phosphatidylcholine ⇌ {\displaystyle...

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Sphingolipid
Selasa, 2026-08-11 03:46:43

be formed by addition of head groups to ceramide or phytoceramide: Sphingomyelins have a phosphocholine or phosphoethanolamine molecule with an ester...

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Sphingomyelin deacylase
Sabtu, 2025-07-12 18:33:17

Sphingomyelin deacylase (EC 3.5.1.109, SM deacylase, GcSM deacylase, glucosylceramide sphingomyelin deacylase, sphingomyelin glucosylceramide deacylase...

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Ceramide
Selasa, 2026-08-11 20:27:35

membrane of eukaryotic cells, since they are component lipids that make up sphingomyelin, one of the major lipids in the lipid bilayer. Contrary to previous...

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Choline
Selasa, 2026-07-28 17:13:07

Fat-soluble choline-containing compounds (phosphatidylcholines and sphingomyelins) are either hydrolyzed by phospholipases or enter the lymph incorporated...

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Fluoxetine
Selasa, 2026-08-11 23:11:13

sphingomyelinase, a key regulator of ceramide levels which derives ceramide from sphingomyelin. Fluoxetine has a direct interaction with Tropomyosin receptor kinase...

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Milk fat globule membrane
Kamis, 2025-12-04 02:54:14

a source of multiple bioactive compounds, including phospholipids, sphingomyelins, gangliosides, glycolipids, glycoproteins, and carbohydrates that have...

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Eisenia fetida
Rabu, 2026-08-05 22:23:17

membranes contain significant amounts of sphingomyelin. (Lysenin is also toxic to organisms lacking sphingomyelin in their cell walls, including Bacillus...

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Sphingosine
Selasa, 2026-04-21 03:26:17

part of sphingolipids, a class of cell membrane lipids that include sphingomyelin, an important phospholipid. Sphingosine can be phosphorylated in vivo...

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Jorge Odón
Senin, 2026-08-17 22:36:15

blood sampling Apt test Kleihauer–Betke test Lung maturity Lecithin–sphingomyelin ratio Lamellar body count Fetal fibronectin test Other Cardiotocography...

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ENPP7
Minggu, 2025-09-28 22:17:50

pyrophosphatase/phosphodiesterase family member 7 (E-NPP 7) also known as alkaline sphingomyelin phosphodiesterase (Alk-SMase) or intestinal alkaline sphingomyelinase...

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Phosphorylethanolamine
Minggu, 2025-10-05 01:32:39

termed a glycerophospholipid and the other a sphingomyelin, or more specifically within the sphingomyelin class, a sphingophospholipid. Phosphorylethanolamine...

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Phosphatidylcholine
Senin, 2026-08-03 00:58:35

component of the pulmonary surfactant, and is often used in the lecithin–sphingomyelin ratio to calculate fetal lung maturity. While phosphatidylcholines are...

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Lysenin
Minggu, 2026-03-01 20:57:48

as a soluble monomer that binds specifically to a membrane receptor, sphingomyelin in the case of lysenin. After attaching to the membrane, the oligomerization...

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Sea anemone cytotoxic protein
Kamis, 2026-02-26 02:32:18

highly basic peptides. These cytolysins form cation-selective pores in sphingomyelin-containing membranes. Examples include equinatoxins (from Actinia equina)...

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Acid sphingomyelinase
Senin, 2025-09-29 15:58:50

sphingomyelinase (SMase) family, responsible for catalyzing the breakdown of sphingomyelin to ceramide and phosphorylcholine. They are organized into alkaline...

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Pulmonary alveolus
Rabu, 2026-07-22 01:51:56

infants causes infant respiratory distress syndrome (IRDS). The lecithin–sphingomyelin ratio is a measure of fetal amniotic fluid to indicate lung maturity...

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Chemotherapy
Senin, 2026-08-10 11:51:27

(S1P) has shown similar effect, but its mechanism of inhibiting the sphingomyelin apoptotic pathway may also interfere with the apoptosis action of chemotherapy...

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Ceramide cholinephosphotransferase
Sabtu, 2024-06-22 07:43:23

+ sphingomyelin Thus, the two substrates of this enzyme are CDP-choline and N-acylsphingosine, whereas its two products are CMP and sphingomyelin. This...

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Sicarius (spider)
Selasa, 2026-06-16 13:28:24

dermonecrotic venom that contains sphingomyelinase D, an enzyme in the sphingomyelin phosphodiesterase family. It is somewhat unique to them, otherwise only...

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Membrane lipid
Kamis, 2025-11-06 00:37:09

hydrocarbon chain. In sphingomyelin and glycolipids, the amino group of sphingosine is linked to FAs by an amide bond. In sphingomyelin the primary hydroxyl...

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SMS2
Senin, 2019-12-30 11:05:09

SMS2 may refer to: Sphingomyelin synthase, an enzyme Small Multitasking System 2 SMS-2 weather satellite SMS (disambiguation) This disambiguation page...

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Liquid ordered phase
Sabtu, 2022-03-12 01:21:51

combining cholesterol with a phospholipid and/or sphingolipids e.g. sphingomyelin. This phase has been related to lipid rafts that may exist in plasma...

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Red blood cell
Rabu, 2026-08-12 02:46:38

disposed, as shown below: Outer monolayer Phosphatidylcholine (PC); Sphingomyelin (SM). Inner monolayer Phosphatidylethanolamine (PE); Phosphoinositol...

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Amniotic fluid
Rabu, 2026-07-15 17:36:32

L/S ratio test (lecithin/sphingomyelin). This test is used to determine fetal lung maturity. Both lecithin and sphingomyelin are lung surfactants that...

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Chromosome 2
Senin, 2026-05-18 12:21:02

solute carrier family 40 (iron-regulated transporter), member 1 SMPD4: Sphingomyelin phosphodiesterase 4 SP140: encoding protein SP140 nuclear body protein...

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Metabolism
Jumat, 2026-07-24 13:05:18

the basic structure exist, including backbones such as sphingosine in sphingomyelin, and hydrophilic groups such as phosphate in phospholipids. Steroids...

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Glycerophospholipid
Jumat, 2025-12-12 11:13:43

brain, as it helps with reduced stress and improved memory. Sphingomyelin Sphingomyelin is a type of sphingolipid, which contains a backbone of sphingoid...

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Myelin
Minggu, 2026-08-16 09:24:34

glycolipid called galactocerebroside. The intertwining hydrocarbon chains of sphingomyelin strengthen the myelin sheath. Cholesterol is an essential lipid component...

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Phospholipid
Selasa, 2026-08-11 05:13:09

Sphingolipid Ceramide phosphorylcholine (Sphingomyelin) (SPH) Ceramide phosphorylethanolamine (Sphingomyelin) (Cer-PE) Ceramide phosphoryllipid Phospholipids...

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Surfactant
Minggu, 2026-08-02 11:12:53

phosphatidylserine, phosphatidylethanolamine, phosphatidylcholine, and sphingomyelins. Lauryldimethylamine oxide and myristamine oxide are two commonly used...

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List of unsaturated fatty acids
Kamis, 2026-03-26 02:29:44

Nervonic acid has 24 carbons, is found in brain glycolipids (Nervon) and sphingomyelin, and is a cis-15-mono-unsaturated fatty acid. C23H45CO2H, IUPAC organization...

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SMPD4
Kamis, 2025-07-17 01:38:26

Sphingomyelin phosphodiesterase 4 is an enzyme that in humans is encoded by the SMPD4 gene. GRCh38: Ensembl release 89: ENSG00000136699 – Ensembl, May...

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Lipid-based nanoparticle
Senin, 2026-07-06 11:59:35

these surfactants. Biological membrane lipids, such as phospholipids, sphingomyelins, bile salts (sodium taurocholate), and sterols (cholesterol) are used...

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Monensin
Minggu, 2026-08-16 16:49:43

synthesis of plasma membrane sphingomyelin by blocking transport of ceramide through the Golgi: evidence for two sites of sphingomyelin synthesis in BHK cells"...

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Zinc-dependent phospholipase C
Sabtu, 2023-08-19 09:06:51

on phosphatidylcholine, it also shows weak catalytic activity with sphingomyelin and phosphatidylinositol. Sequence studies have shown the protein to...

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SMS1
Sabtu, 2023-12-30 02:37:47

SMS1 may refer to: Sphingomyelin synthase, an enzyme SMS-1, weather satellite, part of the NASA program Synchronous Meteorological Satellite SMS (disambiguation)...

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Obstetrics
Rabu, 2026-08-12 12:43:23

factor for infant respiratory distress syndrome. Typically, a lecithin:sphingomyelin ratio greater than 1.5 is associated with increased lung maturity. Nonstress...

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Lecithinase C
Minggu, 2025-07-06 15:26:19

phosphocholine The bacterial enzyme is a zinc protein. It also acts on sphingomyelin and phosphatidylinositol. Druzhinina KV, Kritsman MG (1952). "[Lecithinase...

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Corynebacterium pseudotuberculosis
Kamis, 2026-02-19 23:32:40

bond–cleaving exotoxin that provides the bacterium with the ability to cleave sphingomyelin, which is a glycerophospholipid eukaryotic cell-wall component, so by...

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SMPD3
Sabtu, 2025-07-19 14:19:09

1073/pnas.97.11.5895. PMC 18530. PMID 10823942. "Entrez Gene: SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)"...

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Cholesterol-dependent cytolysin
Minggu, 2026-05-24 23:19:01

that CDC would associate with lipid rafts. A later study showed that sphingomyelin, a necessary component of lipid raft formation, inhibited rather than...

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Citicoline
Selasa, 2026-06-16 06:54:45

neuroprotective effects due to its preservation of cardiolipin and sphingomyelin, preservation of arachidonic acid content of phosphatidylcholine and...

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Phosphodiesterase
Selasa, 2026-08-11 02:00:32

of phosphodiesterases, including phospholipases C and D, autotaxin, sphingomyelin phosphodiesterase, DNases, RNases, and restriction endonucleases (which...

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Lipid raft
Senin, 2026-08-17 14:41:14

surrounding bilayer. Also, lipid rafts are enriched in sphingolipids such as sphingomyelin, which is typically elevated by 50% compared to the plasma membrane...

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Exosome (vesicle)
Minggu, 2026-08-16 12:31:47

lipid- dependent mechanisms. Exosomes are enriched in cholesterol, sphingomyelin, saturated phosphatidylcholine and phosphatidylethanolamine as compared...

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Infant respiratory distress syndrome
Jumat, 2026-08-14 21:29:12

point-of-care method for predicting IRDS by measuring the lecithin-sphingomyelin ratio (L/S) in gastric aspirate (GA). The new method, which is based...

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Ctenus captiosus
Minggu, 2025-11-02 14:13:02

evidence was circumstantial and an assay of the venom did not find Sphingomyelin phosphodiesterase D. While there have been reports of bites being harmful...

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STX4
Selasa, 2025-07-15 11:48:34

ontology Molecular function SNAP receptor activity protein binding sphingomyelin phosphodiesterase activator activity SNARE binding Cellular component...

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Cyanocobalamin
Selasa, 2026-07-28 22:16:43

used for DNA methylation and to make phospholipid membranes, choline, sphingomyelin, acetylcholine, and other neurotransmitters. The metabolism of propionyl-CoA...

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Cerebral folate deficiency
Selasa, 2025-09-30 14:15:45

S-adenosyl homocysteine; SAM: S-adenosyl-methionine; Ser: Serine; SHMT: serine-hydroxy methyl transferase; SM: sphingomyelin. Figure 1 from Mafi et al., 2020....

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Staphylococcus epidermidis
Sabtu, 2026-05-16 05:22:11

mechanisms, skin commensals interact with infectious agents like pathogens. Sphingomyelin phosphodiesterase is the main driver in the S. epidermidis production...

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Calcineurin-like phosphoesterase
Minggu, 2024-08-11 23:36:12

phosphoesterases, including protein phosphoserine phosphatases, nucleotidases, sphingomyelin phosphodiesterases and 2'-3' cAMP phosphodiesterases as well as some...

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SPH
Selasa, 2026-07-14 04:17:33

MediaWorks Small penis humiliation Smoothed-particle hydrodynamics Sphingomyelin Self-propelled howitzer, a type of self-propelled artillery This disambiguation...

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Carbon-11-choline
Jumat, 2026-04-24 03:52:10

Choline occurs in the head groups of phosphatidylcholine and sphingomyelin, which are abundant in cell membranes. It is the precursor for the neurotransmitter...

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Ambadi seed oil
Sabtu, 2025-06-28 07:04:05

Medium (C12–C14) and long (C22–C24) chain fatty acids are less than 1%. Sphingomyelin (4.42% of the total phospholipids), phosphatidyl ethanolamine (12.8%)...

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Phospholipid scramblase
Minggu, 2025-11-23 05:51:11

outer-leaflet, facing the outside environment, contains phosphatidylcholine and sphingomyelin. Scramblase is an enzyme, present in the cell membrane, that can transport...

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List of medical abbreviations: L
Minggu, 2026-08-16 04:10:45

lipase LPP lichen planopilaris LQTS long QT syndrome L/S lecithin-to-sphingomyelin ratio LS lichen sclerosus Lynch syndrome LSA lichen sclerosis et atrophicus...

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SGMS1
Selasa, 2025-07-15 11:45:11

"Expression cloning of a human cDNA restoring sphingomyelin synthesis and cell growth in sphingomyelin synthase-defective lymphoid cells". The Journal...

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Biosynthesis
Senin, 2026-02-23 11:56:24

are particularly abundant in the central nervous system. For example, sphingomyelin is part of the myelin sheath of nerve fibers. Sphingolipids are formed...

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CD1
Senin, 2026-02-23 04:27:12

binds to the A' binding pocket (the left side of CD1a). Sulfatide and sphingomyelin can be considered antagonists for CD1 autoreactive cells, as they have...

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List of EC numbers (EC 3)
Selasa, 2026-07-21 19:09:27

diacylglycerol-lyase EC 3.1.4.11: phosphoinositide phospholipase C EC 3.1.4.12: sphingomyelin phosphodiesterase EC 3.1.4.13: serine-ethanolaminephosphate phosphodiesterase...

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Luxol fast blue stain
Selasa, 2026-06-23 09:41:42

phosphotidyl choline, phosphotidyl ethanolamine, phosphotidyl serine, and sphingomyelin. Together, these phosphoglycerides make up 27.6% of the dry weight of...

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Chlorisondamine
Selasa, 2024-10-22 22:39:52

shown to form noncovalent complexes with various biomolecules including sphingomyelin and other associated glycolipids. Woods AS, Moyer SC, Wang HY, Wise...

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Ceramide phosphoethanolamine synthase
Senin, 2025-11-10 11:35:49

bifunctional enzyme that produces both CPE and sphingomyelin, thus also functioning as a sphingomyelin synthase. Both mammalian CPE synthases, SMS2 and...

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Combined malonic and methylmalonic aciduria
Rabu, 2026-08-12 06:16:14

in particular lipid-mediated signaling. ceramides are reduced, while sphingomyelin—a plasma membrane component that contributes to the efficiency of signal...

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Phosphorylcholine
Jumat, 2025-10-03 22:55:46

platelet-activating factor; the phospholipid phosphatidylcholine and sphingomyelin, the only phospholipid of the membrane that is not built with a glycerol...

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Unilamellar liposome
Rabu, 2026-02-11 16:31:37

phosphatidylethanolamine, phosphatidylserine, phosphatidylinositol, and sphingomyelin are some of the most common lipids most animal cell membranes. These...

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SMPD1-associated Niemann–Pick disease
Selasa, 2025-12-09 02:24:24

required to metabolize the lipid sphingomyelin. If sphingomyelinase is absent or not functioning properly, sphingomyelin cannot be metabolized properly...

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ABC transporter
Minggu, 2026-07-26 02:42:19

phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylserine (PS), sphingomyelin (SM), and glucosylceramide (GlcCer). Multispecific transport of diverse...

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Sicarius ornatus
Senin, 2026-03-02 20:12:07

vitro and ex vivo, and like Loxosceles, it is capable and hydrolyzes sphingomyelin, induce cell death of keratinocytes and complement-dependent hemolysis...

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List of investigational Parkinson's disease drugs
Minggu, 2026-08-09 16:23:19

[102] BXQ-350 (SapC; SapC-DOPS; sphingolipid activator protein C) – sphingomyelin phosphodiesterase stimulant and sphingosine 1-phosphate stimulant [103]...

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Phospholipase C
Minggu, 2026-07-12 14:38:04

with eukaryotic cell membranes and hydrolyzing phosphatidylcholine and sphingomyelin, leading to cell lysis. Zinc-metallophospholipases C: Clostridium perfringens...

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Fred Kummerow
Selasa, 2025-02-18 16:38:28

J. Clin. Nutr. 32, 58–83 (1979). Kummerow FA. Interaction between sphingomyelin and oxysterols contributes to atherosclerosis and sudden death. Am....

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Fluid mosaic model
Sabtu, 2026-04-18 06:24:03

Christie, William (Bill) W. "Sphingolipids, Membrane Rafts and Caveolae - sphingomyelin and cholesterol - structure, occurrence, biochemistry and function"...

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Staphylococcus aureus beta toxin
Sabtu, 2024-12-21 22:16:50

and macrophages. Susceptible cells are subject to lysis of exposed sphingomyelin on their membrane surfaces. The beta toxin exhibits maximum activity...

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Lipid bilayer
Minggu, 2026-08-02 06:35:06

the outer (extracellular) leaflet is based on phosphatidylcholine, sphingomyelin and a variety of glycolipids. In some cases, this asymmetry is based...

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Low-affinity nerve growth factor receptor
Senin, 2026-08-17 20:28:18

PMC 2847487. PMID 20036257. Nicol GD (October 2008). "Nerve growth factor, sphingomyelins, and sensitization in sensory neurons". Sheng Li Xue Bao. 60 (5): 603–604...

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Outline of organic chemistry
Rabu, 2026-08-12 14:09:34

Glycophosphatidylinositols Isoprenoids Phospholipids Sphingolipids Ceramides Sphingomyelins Terpenes Monoterpenes Diterpenes Triterpenes Tetraterpenes Sesquiterpenes...

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Loxoscelism
Senin, 2026-06-22 10:56:58

D Toxins of Brown Spider Venom Convert Lysophosphatidylcholine and Sphingomyelin to Cyclic Phosphates". PLOS ONE. 8 (8) e72372. Bibcode:2013PLoSO...872372L...

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Sphingosine-1-phosphate
Jumat, 2025-08-22 06:19:40

in fertility preservation. However, its mechanism of inhibiting the sphingomyelin apoptotic pathway may also interfere with the apoptosis action of chemotherapy...

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Hemolysin
Selasa, 2025-09-30 11:53:04

mechanism was discovered to be the hydrolysis of a specific membrane lipid, sphingomyelin, which accounts for 50% of the cell's membrane. This degradation was...

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Antimicrobial peptides
Senin, 2026-07-27 10:27:29

membranes are usually made of zwitterionic phosphatidylcholine and sphingomyelin, even though a small portion of the membrane's outer surfaces contain...

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Membrane fluidity
Jumat, 2026-07-31 05:32:16

saturated hydrocarbon chains. Incorporation of particular lipids, such as sphingomyelin, into synthetic lipid membranes is known to stiffen a membrane. Such...

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Phosphatidylethanolamine N-methyltransferase
Sabtu, 2025-11-15 07:36:31

metabolic process negative regulation of cell population proliferation sphingomyelin biosynthetic process phosphatidylcholine biosynthetic process blastocyst...

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Sphingolipidoses
Selasa, 2026-02-24 05:28:57

accepted treatments Prognosis Niemann-Pick disease Sphingomyelinase Sphingomyelin in brain and RBCs Mental retardation Spasticity Seizures Hepatosplenomegaly...

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Actinia cari
Rabu, 2026-05-20 02:38:21

all three caritoxins was permanently and irreversibly inhibited by sphingomyelin. "WoRMS - World Register of Marine Species - Actinia cari Delle Chiaje...

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PRKCD
Senin, 2025-08-18 18:34:47

regulation of insulin receptor signaling pathway positive regulation of sphingomyelin catabolic process cell chemotaxis cell cycle negative regulation of...

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FIASMA
Senin, 2025-10-06 13:11:54

This enzyme is mainly located within the lysosome, where it cleaves sphingomyelin to ceramide and sphingosine, the latter of which is then phosphorylated...

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List of MeSH codes (D10)
Kamis, 2025-07-17 00:48:15

390.470.675.200.906 – trihexosylceramides MeSH D10.390.470.675.870 – sphingomyelins MeSH D10.390.470.806 – psychosine MeSH D10.390.700.700 – polyisoprenyl...

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Johann Ludwig Wilhelm Thudichum
Jumat, 2025-07-18 00:03:42

and characterized numerous compounds of the brain, such as cephalin, sphingomyelin, galactose, lactic acid and sphingosine. In 1884 he explained his findings...

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Amniocentesis
Rabu, 2026-05-20 07:18:06

amniocentesis. Several tests are available, including the lecithin-sphingomyelin ratio ("L/S ratio"), the presence of phosphatidylglycerol (PG), and...

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Pleurotolysin
Selasa, 2026-08-18 23:08:01

Pleurotolysin (TC# 1.C.97.1.1), a sphingomyelin-specific cytolysin. Its A (17 kDa; Q8X1M9) and B (59 kDa; Q5W9E8) components are assembled into a transmembrane...

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Michael Schick (physicist)
Jumat, 2025-07-18 14:39:17

characteristic composition. One kind of region is rich in saturated sphingomyelin and cholesterol, while the other is rich in unsaturated lipids. Eschewing...

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Ernst Klenk
Selasa, 2026-07-14 19:28:39

cause of Niemann-Pick’s lipidosis as the storage of large amounts of sphingomyelin in the brain, liver and spleen. He found that cerebroside accumulated...

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ASM
Kamis, 2026-01-29 11:58:33

contemporary hip hop trio currently signed with Chinese Man records Sphingomyelin phosphodiesterase 1 or acid sphingomyelinase Abelian sandpile model...

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Choline kinase
Senin, 2026-06-29 18:59:51

membrane-related enzymes. CK also plays a vital role in the production of sphingomyelin, another important membrane phospholipid and in the regulation of cell...

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Chromosome 11
Selasa, 2026-07-28 08:02:51

22 SMAP1: small acidic protein SMCO4: encoding protein SMCO4 SMPD1: sphingomyelin phosphodiesterase 1, acid lysosomal (acid sphingomyelinase) SNHG1: encoding...

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Photobacterium damselae subsp. damselae
Sabtu, 2026-05-30 20:14:58

called damselysin (Dly). Dly is a phospholipase D with activity against sphingomyelin. This toxin exerts strong hemolytic activity in the erythrocytes across...

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Igor B. Dawid
Kamis, 2026-08-13 02:19:50

chemistry and biochemistry from University of Vienna in 1960, focused on sphingomyelin structure. He continued his studies of biochemistry in postdoctoral...

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Ludwig Pick
Rabu, 2026-03-04 05:20:23

Niemann–Pick disease: A biochemical disorder affecting a lipid fat called sphingomyelin, which usually results in progressive enlargement of the liver and spleen...

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1-Deoxysphingolipids
Jumat, 2026-07-03 03:09:43

phosphorylated and they can neither converted into complex lipids as sphingomyelins and glycosphingolipids (galactosylceramides, gangliosides, cerebrosides...

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Thermotoga maritima
Kamis, 2025-10-02 16:50:29

"Sphingolipid biosynthesis de novo by rat hepatocytes in culture. Ceramide and sphingomyelin are associated with, but not required for, very low density lipoprotein...

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Julio Licinio
Minggu, 2026-08-16 15:01:02

his team showed that inflammation-mediated up-regulation of secretory sphingomyelin phosphodiesterase in vivo represents a possible link between inflammatory...

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List of EC numbers (EC 2)
Selasa, 2026-07-21 21:04:30

EC 2.7.8.26: adenosylcobinamide-GDP ribazoletransferase EC 2.7.8.27: sphingomyelin synthase EC 2.7.8.28: 2-phospho-L-lactate transferase EC 2.7.8.29:...

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SPATCCM
Sabtu, 2026-08-15 00:19:21

precursor to several essential compounds, including phosphatidylserine, sphingomyelin, glycine, and D-serine. Diagnosis of SPATCCM generally relies on whole...

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Nocturnin
Selasa, 2026-08-11 18:52:28

protein fold is similar to that of DNase I, AP endonuclease, INPP5B, Sphingomyelin phosphodiesterase, TDP2, PDE12, and CNOT6L. As in the other EEP members...

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Apolipoprotein D
Sabtu, 2026-08-08 01:33:55

secretions; retinoic acid, which is involved in cellular differentiation; and sphingomyelin and sphingolipids, which are major components of HDL and cell membranes...

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Alexa Fluor
Jumat, 2026-07-24 08:35:17

M.; Kobayashi, T. (25 September 2018). "Protein Probes to Visualize Sphingomyelin and Ceramide Phosphoethanolamine". Chem. Phys. Lipids. 216: 132–141...

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GPR132
Kamis, 2025-07-17 23:45:15

a receptor for a phospholipid, lysophosphatidylcholine (LPC), and a Sphingomyelin, sphingosylphosphorylcholine. However, these studies did not give evidence...

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Glycosphingolipid
Sabtu, 2026-03-21 22:22:03

certain species of bacteria, such as members of the genus Sphingomonas. Sphingomyelin Charles Chalfant; Maurizio Del Poeta (2010). Sphingolipids as signaling...

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Felix Armin Randow
Senin, 2026-05-18 13:12:01

showed that stressed but otherwise intact phagosome membranes expose sphingomyelin on their cytosolic surface, providing an early indicator of impending...

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MDX-1097
Minggu, 2026-02-01 04:22:37

that is presented when kappa free light chain (kFLC) associates with sphingomyelin in the cell membrane. KappaMab does not bind to kappa immunoglobulin...

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Egg lecithin
Senin, 2025-08-18 04:13:49

cell membrane. Other components include phosphatidylethanolamine and sphingomyelin. Egg lecithin is usually extracted chemically using ethanol, acetone...

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Nanoparticles for drug delivery to the brain
Minggu, 2025-12-14 22:55:31

bilayers, lamellae, made of biocompatible and biodegradable lipids such as sphingomyelin, phosphatidylcholine, and glycerophospholipids. Cholesterol, a type...

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Lamellar bodies
Selasa, 2025-07-29 06:59:05

patients of asteatotic eczema (also known as winter eczema). Lecithin–sphingomyelin ratio Ishida-Yamamoto, Akemi; Kishibe, Mari (23 March 2011). "Involvement...

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Major facilitator superfamily
Minggu, 2026-02-08 01:28:46

diacylglycerols and decreases in lysophosphatidylcholine, cholesterol ester and sphingomyelin lipids. Diabetes mellitus SLCO1B3 Q9NPD5 Mediates the Na(+)-independent...

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Ceramide synthase 5
Rabu, 2026-07-29 00:35:00

YH, Bielawski J, Kraveka JM, et al. (2008). "Ceramide generated by sphingomyelin hydrolysis and the salvage pathway is involved in hypoxia/reoxygenation-induced...

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Peripheral membrane protein
Rabu, 2026-08-05 05:02:26

phosphodiesterase, cleaves phosphodiester bonds. Processing of lipids such as sphingomyelin. saposin domain and connector regions with a metallophosphate catalytic...

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MPPC
Minggu, 2023-04-09 12:52:02

Microsoft Point-to-Point Compression Menlo Park Presbyterian Church Milk Sphingomyelin (1-Myristoyl,2-Palmitoyl-sn-Glycero 3-PhosphoCholine) Multi-pixel photon...

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Polska Roma
Kamis, 2026-03-26 06:27:11

the sea anemone Stoichacis helianthus, including specific binding to sphingomyelin". Proceedings of the National Academy of Sciences of the United States...

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Vijendra K. Singh
Sabtu, 2026-04-25 00:50:31

including steroids, intravenous immunoglobulin, plasmapheresis, and sphingomyelin." Singh V. K., Lin SX, Newell E, Nelson C. (2002). "Abnormal measles-mumps-rubella...

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SMPD2
Sabtu, 2025-07-19 14:19:07

Sphingomyelin phosphodiesterase 2 is an enzyme that in humans is encoded by the SMPD2 gene. GRCh38: Ensembl release 89: ENSG00000135587 – Ensembl, May...

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Index of biophysics articles
Selasa, 2025-09-02 20:37:54

cell adhesion molecules Solute pumping Sorting and assembly machinery Sphingomyelin Spinal locomotion Sports biomechanics Steady state (biochemistry) Stephen...

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List of human blood components
Jumat, 2026-07-10 22:10:25

total 2-2.5 ×10−1 8-9 ×10−2 Somatotropin growth hormone 4-140 ×10−10 Sphingomyelin 1.5-1.85 ×10−3 1-4 ×10−4 Succinic acid 5 ×10−6 Sugar, total 7-11 ×10−4...

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Fibrinoid necrosis
Kamis, 2026-08-13 01:46:27

including endothelial cells, and trigger the enzymatic hydrolysis of sphingomyelin and the generation of ceramide. Ceramide subsequently increases the...

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Surfactant–albumin ratio
Senin, 2024-11-11 23:43:06

C (1995). "Amniotic fluid polarization of fluorescence and lecithin/sphingomyelin ratio decision criteria assessed". Yale J Biol Med. 68 (3–4): 101–17...

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Hopanoids
Sabtu, 2026-05-16 01:59:07

demonstrated to promote condensation and inhibit gel-phase formation in both sphingomyelin monolayers and monolayers of glycan-modified lipid A. Furthermore, both...

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Long-chain fatty acid transport protein 1
Minggu, 2025-07-20 14:31:44

channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells". Journal of Lipid Research...

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Hydrophobic mismatch
Rabu, 2025-09-17 22:44:43

retention in the Golgi. Rafts are membrane domains enriched in cholesterol, sphingomyelin (SM), and certain membrane proteins. Rafts have putative roles in many...

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Yusuf A. Hannun
Rabu, 2026-08-12 07:32:01

12604-9. Accessed 19 May 2020. T. Okazaki, R. Bell. and Y.A. Hannun "Sphingomyelin turnover induced by vitamin D3 in HL-60 cells: Role in cell differentiation"...

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Lipid signaling
Rabu, 2026-06-17 07:49:27

proteins in serum. Ceramide (Cer) can be generated by the breakdown of sphingomyelin (SM) by sphingomyelinases (SMases), which are enzymes that hydrolyze...

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List of MeSH codes (D09)
Jumat, 2026-06-19 23:19:40

420.525.200.906 – trihexosylceramides MeSH D09.400.410.420.525.870 – sphingomyelins MeSH D09.400.410.420.806 – psychosine MeSH D09.400.410.475 –...

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Ceramide synthase 1
Sabtu, 2025-07-19 12:22:54

neuronal CerS1 decreased levels of sphingolipids, hexosylceramides, and sphingomyelin. Although the brains in these mice appeared to develop normally, researchers...

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Roscoe Brady
Senin, 2026-01-19 23:52:33

1112–1115. Brady RO, Kanfer JN, Mock MB, Fredrickson DS. The metabolism of sphingomyelin. II. Evidence of an enzymatic deficiency in Niemann-Pick disease. Proc...

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SPTLC2
Kamis, 2025-10-02 11:35:39

for the synthesis of various other molecules including, ceramides, sphingomyelin, cerebrosides and globosides. Epidermal ceramides are critical for normal...

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Atg8ylation
Minggu, 2026-08-16 09:37:08

stressed membranes via TECPR1, which recognizes the citofacially displayed sphingomyelin misplaced and exposed on perturbed membranes. Atg8ylation is an important...

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SPTLC1
Selasa, 2025-07-15 11:48:05

process sphinganine biosynthetic process sphingosine biosynthetic process sphingomyelin biosynthetic process positive regulation of lipophagy lipid metabolism...

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Arcanobacterium haemolyticum
Selasa, 2026-07-21 15:37:56

neuraminidase and a phospholipase D (PLD) acting preferentially on sphingomyelin. PLD is known to result in tissue damage, but the role in disease of...

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Battenin
Minggu, 2026-02-08 01:26:19

organization macroautophagy amyloid precursor protein catabolic process sphingomyelin metabolic process vacuolar transport transport regulation of intracellular...

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Phospholipase D
Minggu, 2026-08-16 09:32:58

The enzyme is sequestered inactive in lipid micro-domains rich in sphingomyelin but depleted of its PC substrate. A local increase in PIP2 or decrease...

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Ceramide-activated protein phosphatase
Rabu, 2025-12-10 13:17:00

the cellular stress response (Janssens & Goris, 2001). Products of sphingomyelin metabolism, activated by stress, seem to react with sphingolipids to...

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Perfringolysin O
Jumat, 2026-07-24 10:00:00

phospholipids require lower cholesterol concentrations for binding, whereas sphingomyelin reduces PFO binding by limiting cholesterol exposure at the membrane...

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Smoothened
Minggu, 2026-08-16 09:45:11

levels of accessible cholesterol due to sequestering of cholesterol by sphingomyelin. In addition to cholesterol's role as a Hh pathway agonist, it has been...

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Cafileria
Selasa, 2026-08-18 03:55:56

phenomenon happens in mammalian cells, in association with changes in sphingomyelin metabolism, but in the case of Cafileria the mechanism responsible is...

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Multi-parametric surface plasmon resonance
Minggu, 2026-07-19 21:11:58

"Toxin-induced pore formation is hindered by intermolecular hydrogen bonding in sphingomyelin bilayers". Biomembranes. 1858 (6): 1189–1195. doi:10.1016/j.bbamem.2016...

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FA2H
Minggu, 2025-10-05 05:22:01

Edvardson S, Bielawski J, Hama H, Saada A (May 2011). "2-Hydroxylated sphingomyelin profiles in cells from patients with mutated fatty acid 2-hydroxylase"...

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Henrik Verder
Senin, 2026-04-06 19:54:00

microbubble test, lamellar body counts (LBC) and measurements of lecithin-sphingomyelin ratio (L/S) with chemometrics, involving a collaboration with Agnar...

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Biomarker discovery
Rabu, 2025-10-22 18:50:36

particles from coronary bypass patients contained significantly less sphingomyelin relative to phosphatidylcholine and higher triglycerides relative to...

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OB-fold
Minggu, 2025-10-05 14:11:22

Kolesnick RN (September 1993). "Tumor necrosis factor activation of the sphingomyelin pathway signals nuclear factor kappa B translocation in intact HL-60...

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Phallolysin
Rabu, 2025-10-08 21:52:52

phospholipids with a negative net charge, phosphatidylcholine, and sphingomyelin containing liposomes. However, phospholipid-membranes are only susceptible...

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Alan W. Bernheimer
Jumat, 2026-05-15 23:11:18

the sea anemone Stoichacis helianthus, including specific binding to sphingomyelin". Proceedings of the National Academy of Sciences. 73 (2): 467–471....

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List of MeSH codes (D08)
Jumat, 2025-07-18 00:13:51

277.352.640.700.710 – phospholipase d MeSH D08.811.277.352.640.750 – sphingomyelin phosphodiesterase MeSH D08.811.277.352.650 – phosphoric monoester hydrolases...

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CER-001
Selasa, 2025-09-30 13:23:03

protein of natural HDL, together with two phospholipids, which are: sphingomyelin and dipalmitoyl-phosphatidylglycerol. CER-001 is designed to mimic the...

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COL4A3BP
Rabu, 2026-07-29 00:39:33

the ER, then is transferred by CERT to Golgi where it is converted to sphingomyelin (SM). There are two pathways through which this transfer takes place:...

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Modeccin
Kamis, 2026-06-11 00:30:59

C18-cer has no effect on modeccin toxicity, as well as sphingosine and sphingomyelin. de Ruijter A. "Adenia digitata (Harv.) Engl". PROTA4U. Plant Resources...

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Group 1 CD1-restricted T cells
Minggu, 2023-09-24 13:15:09

including gangliosides (GM1,GD1a, GD1b, GT1b, and GQ1b), sulfatides, sphingomyelin, phophatidylglycerol, lysophospholipids, squalene, wax esters, and triacylglycerides...

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