Grisolía published over 400 scientific papers and was involved with numerous organizations in Spain and other countries.[1] It is impossible to summarize such a large output in a few words, but some references give an indication of his work and publications, many of which were concerned with enzymes. Much of his first work concerned the biochemistry of citrulline,[2] and he later worked on phosphoglycerate mutase,[3] carbamoyl-phosphate synthetase[4][5] and other enzymes.
He has held various positions, including President of the Scientific Coordination Committee of the Human Genome Project for UNESCO.
Creator and secretary of the Valencian Foundation for Advanced Studies and main promoter of the current Rey Jaime I Awards.
Awards
He was appointed Grand Cross of the Orden Civil de Sanidad (Civil Order of Health) in 1984. He was further honoured when he was appointed Grand Cross of Civil Order of Alfonso X, the Wise in 1987. In 1992 he was appointed Grand Cross of the Order of Civil Merit.
^Britton, H G; Carreras, J; Grisolia, S (1971). "Mechanism of action of 2,3-diphosphoglycerate-independent phosphoglycerate mutase". Biochemistry. 10 (24): 4522–4533. doi:10.1021/bi00800a028. PMID5168977.
^Rubio, V; Grisolia, S (1977). "Mechanism of mitochondrial carbamoyl-phosphate synthetase - synthesis and properties of active CO2, precursor of carbamoyl phosphate". Biochemistry. 16 (2): 321–329. doi:10.1021/bi00621a025. PMID13811.
^Rubio, V; Britton, H G; Grisolia, S; Sproat, B S; Lowe, G (1981). "Mechanism of activation of bicarbonate ion by mitochondrial carbamoyl-phosphate synthetase — formation of enzyme-bound adenosine-diphosphate from the adenosine-triphosphate that yields inorganic-phosphate". Biochemistry. 20 (7): 1969–1974. doi:10.1021/bi00510a036. PMID6261808.