Reticulate acropigmentation of Kitamura is a type of pigmentation disorder of the skin.[2] It presents with coloured freckle-like and slightly depressed flat spots arranged in a lace-like pattern on the backs of hands and feet.[2] It tends to occur in skin folds of teenagers and in early adulthood, and darkens over time.[2]
It is inherited in an autosomal-dominant fashion.[2]
The condition is rare.[1] It was first described in Japan, before recognising that is also occurs elsewhere.[2]
Genetics
This condition is associated with mutations in the a disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) gene. This association was first shown in 2013.[citation needed]
