The enzyme R-linalool synthase (EC 4.2.3.26) catalyzes the chemical reaction

geranyl diphosphate + H₂O ${\displaystyle \rightleftharpoons }$ (3R)-linalool + diphosphate

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on phosphates. The systematic name of this enzyme class is geranyl-diphosphate diphosphate-lyase [(3R)-linalool-forming]. Other names in common use include (3R)-linalool synthase, and (−)-3R-linalool synthase.

• Jia JW, Crock J, Lu S, Croteau R, Chen XY (1999). "(3R)-Linalool synthase from Artemisia annua L.: cDNA isolation, characterization, and wound induction". Arch. Biochem. Biophys. 372 (1): 143–9. doi:10.1006/abbi.1999.1466. PMID 10562427.
• Crowell AL, Williams DC, Davis EM, Wildung MR, Croteau R (2002). "Molecular cloning and characterization of a new linalool synthase". Arch. Biochem. Biophys. 405 (1): 112–21. doi:10.1016/S0003-9861(02)00348-X. PMID 12176064.