In enzymology, a phenol beta-glucosyltransferase (EC 2.4.1.35) is an enzyme that catalyzes the chemical reaction

UDP-glucose + a phenol ${\displaystyle \rightleftharpoons }$ UDP + an aryl beta-D-glucoside

Thus, the two substrates of this enzyme are UDP-glucose and phenol, whereas its two products are UDP and aryl beta-D-glucoside.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:phenol beta-D-glucosyltransferase. Other names in common use include UDPglucosyltransferase, phenol-beta-D-glucosyltransferase, UDP glucosyltransferase, UDP-glucose glucosyltransferase, and uridine diphosphoglucosyltransferase. This enzyme participates in starch and sucrose metabolism.

• Dutton GJ (September 1966). "Uridine diphosphate glucose and the synthesis of phenolic glucosides by mollusks". Archives of Biochemistry and Biophysics. 116 (1): 399–405. doi:10.1016/0003-9861(66)90046-4. PMID 5961845.