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The National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs, pronounced as "N C 3 Rs") is a British organization with the goal of reducing the number of animals used in scientific research.[1][2] It is named after the three Rs principles, first described in 1959, for reducing the scale and impact of animal research. It was established in 2004 after the publication of a 2002 House of Lords select committee report on Animals In Scientific Procedures[3][4] As of 2021[update], the chief executive of NC3Rs is Dr Vicky Robinson,[5] who was appointed CBE in the 2015 Birthday Honours "For services to Science and Animal Welfare".[6]
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