King cobra

This article is about the snake. For other uses, see King Cobra (disambiguation).
Not to be confused with Indian cobra.

King cobra
CITES Appendix II (CITES)[1]
Scientific classification Edit this classification
Domain: Eukaryota
Kingdom: Animalia
Phylum: Chordata
Class: Reptilia
Order: Squamata
Suborder: Serpentes
Family: Elapidae
Genus: Ophiophagus
Günther, 1864
Species:
O. hannah
Binomial name
Ophiophagus hannah
(Cantor, 1836)
  Distribution of the king cobra
Synonyms

Genus-level:

The king cobra (Ophiophagus hannah) is a species complex of snakes endemic to Asia. With an average of 3.18 to 4 m (10.4 to 13.1 ft) and a record length of 5.85 m (19.2 ft),[2] it is the world's longest venomous snake and among the heaviest. Under the genus Ophiophagus, it is not phylogenetically a true cobra despite its common name and some resemblance. Spanning from the Indian Subcontinent through Southeastern Asia to Southern China, the king cobra is widely distributed albeit not commonly seen.

Individuals have diversified colouration across its habitats, from black with white strips to unbroken brownish grey, although after taxonomic re-evaluation, it is no longer the sole member of its genus but is now a species complex; these differences in pattern and other aspects may cause the genus to be split into at least four species, spread across its large geographic range.

It chiefly hunts other snakes, including those of its own kind, although other lizards and rodents are occasional prey items. This is the only ophidian that constructs an above-ground nest for its eggs, which are purposefully and meticulously gathered and protected by the female throughout the incubation period.[3] Typical threat display of this elapid includes neck-flap spreading, head raising, hissing and sometimes charging. Capable of striking at a considerable range and height with an immense venom yield, envenomation from this species may induce rapid onset of neurotoxic and cytotoxic symptoms, requiring prompt antivenom administration. Despite the fearsome reputation, aggression toward humans usually only arises from an individual inadvertently exposing itself or being cornered; encounters happen through chance, including negative interactions.

Threatened by habitat destruction, it has been listed as Vulnerable on the IUCN Red List since 2010. Regarded as the national reptile of India, it has an eminent position in the mythology and folk traditions of India, Bangladesh, Sri Lanka and Myanmar.


Etymology

The king cobra is also referred to by the common name "hamadryad", especially in older literature. Hamadryas hannah was the scientific name used by Danish naturalist Theodore Edward Cantor in 1836 who described four king cobra specimens, three captured in the Sundarbans and one in the vicinity of Kolkata.[4] The origin of the species name hannah was not specified during description and has long been uncertain, but may potentially refer to Hannah Sarah Wallich, the eldest daughter of Cantor's uncle, botanist Nathaniel Wallich, who hosted Cantor during his studies in India.[5]

Taxonomy

The genus Ophiophagus was proposed by Günther in 1864 in place of Hamadryas, as the genus Hamadryas was already used for the cracker butterflies.[6] The name is derived from its propensity to eat snakes.[7] Ophiophagus hannah was accepted as the valid name for the king cobra by Charles Mitchill Bogert in 1945 who argued that it differs significantly from Naja species.[8]

It has been suggested that three more king cobra species exist in addition to O. hannah, namely the Sunda king cobra O. bungarus, the Western Ghats king cobra (O. kaalinga) and the Luzon king cobra (O. salvatana). These distinct genetic lineages are geographically isolated and adapted to specific ecological regions.[5]

Synonyms

In 1838, Cantor proposed the name Hamadryas ophiophagus for the king cobra and explained that it has dental features intermediate between the genera Naja and Bungarus.[9] Naia vittata proposed by Walter Elliot in 1840 was a king cobra caught offshore near Chennai that was floating in a basket.[10] This provenance is disputed, as wild king cobras have never occurred near Chennai, and an analysis of this specimen has found it to be more similar to the northern king cobra.[5] Hamadryas elaps proposed by Albert Günther in 1858 were king cobra specimens from the Philippines and Borneo. Günther considered both N. bungarus and N. vittata a variety of H. elaps.[11] Naja ingens proposed by Alexander Willem Michiel van Hasselt in 1882 was a king cobra captured near Tebing Tinggi in northern Sumatra.[12]

The earliest scientific name for the king cobra was Naja bungaroides, given by Friedrich Boie in 1828 based on a juvenile specimen from Java. This description was improperly done, leaving it a nomen nudum at the time. However, Johann Georg Wagler validated the name in 1830 with a sufficient diagnosis, and also proposed a new genus for it, Hoplocephalus. In 1837, Hermann Schlegel used the name Naja bungaroides for his description of the Australian broad-headed snake, which was later reclassified into Wagler's Hoplocephalus, and used the species name Naja bungarus for the king cobra.[13] Since then, the species name Naja/Hoplocephalus bungaroides, originally coined for the king cobra and improperly assigned to the broad-headed snake, became conflated with the broad-headed snake and used as the type species of Hoplocephalus, while the species name Naja bungarus was treated as a junior synonym of the king cobra (until its revival as the species name for the Sunda king cobra in 2024). This longstanding discrepancy, which breaks the principle of priority, was overlooked for nearly two centuries and only discovered in 2024. Due to the long presence of the names Ophiophagus hannah and Hoplocephalus bungaroides in the literature, which would be upended if these two species were reclassified based on this issue, it was decided to maintain the longstanding scientific names for both taxa and designate a new, accurate type specimen for the broad-headed snake.[5]

Evolution

A genetic analysis using cytochrome b,[14] and a multigene analysis showed that the king cobra was an early offshoot of a genetic lineage giving rise to the mambas, rather than the Naja cobras.[15]

A phylogenetic analysis of mitochondrial DNA showed that specimens from Surat Thani Province and Nakhon Si Thammarat Provinces in southern Thailand form a deeply genetically divergent clade from those in northern Thailand, which grouped with specimens from Myanmar and Guangdong in southern China.[16]

Description

Scales of the king cobra
A baby king cobra showing its chevron pattern on the back

The king cobra's skin is olive green with black and white bands on the trunk that converge to the head. The head is covered by 15 drab-coloured and black-edged shields (large scales consistently present between individuals). The muzzle is rounded, and the tongue black. It has two fangs and 3–5 maxillary teeth in the upper jaw, and two rows of teeth in the lower jaw. The nostrils are between two shields. The large eyes have a golden iris and round pupils. Its hood is oval shaped and covered with olive green smooth scales and two black spots between the two lowest scales. Its cylindrical tail is yellowish green above and marked with black.[4] It has a pair of large occipital scales on top of the head, 17 to 19 rows of smooth oblique scales on the neck, and 15 rows on the body. Juveniles are black with chevron shaped white, yellow or buff bars that point towards the head.[17] Adult king cobras are 3.18 to 4 m (10.4 to 13.1 ft) long. The longest known individual measured 5.85 m (19.2 ft).[2][18] Ventral scales are uniformly oval shaped. Dorsal scales are placed in an oblique arrangement.[19]

The king cobra is sexually dimorphic, with males being larger and paler in particular during the breeding season. Males captured in Kerala measured up to 3.75 m (12.3 ft) and weighed up to 10 kg (22 lb). Females captured had a maximum length of 2.75 m (9 ft 0 in) and a weight of 5 kg (11 lb).[20] The largest known king cobra was 5.59 m (18 ft 4 in) long and captured in Thailand.[21] It differs from other cobra species by size and hood. It is larger, has a narrower and longer stripe on the neck.[22]

Distribution and habitat

The king cobra has a wide distribution throughout tropical Asia. It occurs in elevations of 2,000 m (6,600 ft) from the Terai in India and southern Nepal to the Brahmaputra River basin in Bhutan and northeast India, down to Bangladesh, Myanmar, southern China, Cambodia, Thailand, Laos, Vietnam; to the maritime Southeast Asian countries of Malaysia, Singapore, Indonesia and the Philippines.[1]

In northern India, it has been recorded in Garhwal and Kumaon, and in the Sivalik hills and terai regions of Uttarakhand and Uttar Pradesh.[23][24][25] In northeast India, the king cobra has been recorded in northern West Bengal, Sikkim, Assam, Meghalaya, Arunachal Pradesh, Nagaland, Manipur and Mizoram.[26][27] In the Eastern Ghats, it occurs from Tamil Nadu and Andhra Pradesh to coastal Odisha, and also in Bihar and southern West Bengal, especially the Sundarbans.[4][26][28] In the Western Ghats, it was recorded in Kerala, Karnataka and Maharashtra, and also in Gujarat.[26][29][20][30] It also occurs on Baratang Island in the Great Andaman chain.[31] It may have reached the furthest west of its distributional range in extreme western India & eastern Pakistan, in the vicinity of Lahore and Palanpur. These populations have sometimes been thought to be the result of introduction by snake charmers or transport along rivers, but are now more likely considered natural populations. However, it remains uncertain if any populations continue to persist there.[5]

Behaviour and ecology

Like other snakes, a king cobra receives chemical information via its forked tongue, which picks up scent particles and transfers them to a sensory receptor (Jacobson's organ) located in the roof of its mouth.[2] Following envenomation, it swallows its prey whole. Because of its flexible jaws, it can swallow prey much larger than its head. It is considered diurnal because it hunts during the day, but has also been seen at night, rarely.[2]

Diet

Hunting a reticulated python.

The king cobra is an apex predator and dominant over all other snakes except large pythons.[32] Its diet consists primarily of other snakes and lizards, including Indian cobra, banded krait, rat snake, pythons, green whip snake, keelback, banded wolf snake and Blyth's reticulated snake.[33] It also hunts Malabar pit viper and hump-nosed pit viper by following their odour trails.[34] In Singapore, one was observed swallowing a clouded monitor.[35] When food is scarce, it also feeds on other small vertebrates, such as birds, and lizards. In some cases, the cobra constricts its prey using its muscular body, though this is uncommon. After a large meal, it may go for many months without another one because of its slow metabolic rate.[2][36]

Antipredator behavior

Captive king cobras with their hoods extended
Further information: Anti-predator adaptation

The king cobra is not considered aggressive.[37] It usually avoids humans and slinks off when disturbed, but is known to aggressively defend incubating eggs and attack intruders rapidly. When alarmed, it raises the front part of its body, extends the hood, shows the fangs and hisses loudly.[33][38] Wild king cobras encountered in Singapore appeared to be placid, but reared up and struck in self defense when cornered.[39]

The king cobra can be easily irritated by closely approaching objects or sudden movements. When raising its body, the king cobra can still move forward to strike with a long distance, and people may misjudge the safe zone. It can deliver multiple bites in a single attack.[40]

The hiss of the king cobra is a much lower pitch than many other snakes and many people thus liken its call to a "growl" rather than a hiss. While the hisses of most snakes are of a broad-frequency span ranging from roughly 3,000 to 13,000 Hz with a dominant frequency near 7,500 Hz, king cobra growls consist solely of frequencies below 2,500 Hz, with a dominant frequency near 600 Hz, a much lower-pitched frequency closer to that of a human voice. Comparative anatomical morphometric analysis has led to a discovery of tracheal diverticula that function as low-frequency resonating chambers in king cobra and its prey, the rat snake, both of which can make similar growls.[41]

Reproduction

A captive juvenile king cobra in its defensive posture

The female is gravid for 50 to 59 days.[18] The king cobra is the only snake that builds a nest using dry leaf litter, starting from late March to late May.[42] Most nests are located at the base of trees, are up to 55 cm (22 in) high in the centre and 140 cm (55 in) wide at the base. They consist of several layers and have mostly one chamber, into which the female lays eggs.[43] Clutch size ranges from 7 to 43 eggs, with 6 to 38 eggs hatching after incubation periods of 66 to 105 days. Temperature inside nests is not steady but varies depending on elevation from 13.5 to 37.4 °C (56.3 to 99.3 °F). Females stay by their nests between two and 77 days. Hatchlings are between 37.5 and 58.5 cm (14.8 and 23.0 in) long and weigh 9 to 38 g (0.32 to 1.34 oz).[42]

The king cobra was shown to be capable of facultative parthenogenesis.[44] The parthenogenetic mechanism appears to be a variation of meiosis referred to as terminal fusion automixis in which there is fusion of the meiotic products formed at the anaphase II stage of meiosis.[44]

The venom of hatchlings is as potent as that of the adults. They may be brightly marked, but these colours often fade as they mature. They are alert and nervous, being highly aggressive if disturbed.[22]

The average lifespan of a wild king cobra is about 20 years.[45]

Venom

Lateral view of a king cobra skull with fangs

Composition

Venom of the king cobra, produced by the postorbital venom glands, consists primarily of three-finger toxins (3FTx) and snake venom metalloproteinases (SVMPs).[46][47]

Of all the 3FTx, alpha-neurotoxins are the predominant and most lethal components when cytotoxins and beta-cardiotoxins also exhibit toxicological activities.[48][49][50] It is reported that cytotoxicity of its venom varies significantly, depending upon the age and locality of an individual.[51] Clinical cardiotoxicity is not widely observed, nor is nephrotoxicity present among patients bitten by this species, presumably due to the low abundance of the toxins.[40]

SVMPs are the second most protein family isolated from the king cobra's venom, accounting from 11.9% to 24.4% of total venom proteins.[52][53][54] The abundance is much higher than that of most cobras which is usually less than 1%.[55] This protein family includes principal toxins responsible for vasculature damage and interference with haemostasis, contributing to bleeding and coagulopathy caused by envenomation of vipers. While there are such haemorrhagins isolated from the king cobra's venom, they only induce species-sensitive haemorrhagic and lethal activities on rabbits and hares, but with minimal effects on mice.[56] Clinical pathophysiology of the king cobra's SVMPs has yet to be well studied, although its substantial quantity suggests involvement in tissue damage and necrosis as a result of inflammatory and proteolytic activities, which are instrumental for foraging and digestive purposes.[56][40]

Ohanin, a minor vespryn protein component specific to this species, causes hypolocomotion and hyperalgesia in experimental mice. It is believed that it contributes to neurotoxicity on the central nervous system of the victim.[57]

Clinical management

A king cobra's bite, and subsequent envenomation, is an immediate medical emergency in humans or domesticated animals, as, if not treated as soon as possible, death can occur in as little as 30 minutes.[40][58] Local symptoms include dusky discolouration of skin, edema and pain; in severe cases, swelling extends proximally, with necrosis and tissue sloughing that may require amputation.[40] Onset of general symptoms follows while the venom is targeting the victim's central nervous system, resulting in blurred vision, vertigo, drowsiness, and eventual paralysis. If not treated promptly, it may progress to cardiovascular collapse and, subsequently, coma. Death soon follows due to respiratory failure, among other simultaneous and varied system and organ failures.[40]

Polyvalent antivenom of equine origin is produced by Haffkine Institute and King Institute of Preventive Medicine and Research in India.[59] A polyvalent antivenom produced by the Thai Red Cross Society can effectively neutralise venom of the king cobra.[60] In India and Thailand, a concoction (or liquid blend) of turmeric (Curcuma longa) and other potent, medically relevant herbs reportedly creates a strong resilience against the venom of the king cobra when ingested.[61][62] Proper and immediate treatments are critical to avoid death. Successful precedents include a client who recovered and was discharged in 10 days after being treated by accurate antivenom and inpatient care.[58]

It can deliver up to 420 mg venom in dry weight (400–600 mg overall) per bite,[63] with a LD50 toxicity in mice of 1.28 mg/kg through intravenous injection,[64] 1.5 to 1.7 mg/kg through subcutaneous injection,[65] and 1.644 mg/kg through intraperitoneal injection.[63][66][67] For research purposes, up to 1 g of venom was obtained through milking.[52]

Relationship with humans

Conservation

In Southeast Asia, the king cobra is threatened foremost by habitat destruction owing to deforestation and expansion of agricultural land. It is also threatened by wildlife smuggling, as well as by poaching, then sold as bushmeat or turned into snake leather, and for use in traditional Chinese medicine.[1]

The king cobra is listed in CITES Appendix II. It is protected in China and Vietnam.[1] In India, it is placed under Schedule II of Wildlife Protection Act, 1972. Killing a king cobra is punished with imprisonment of up to six years.[68] In the Philippines, king cobras (locally known as banakon) are included under the list of threatened species in the country. It is protected under the Wildlife Resources Conservation and Protection Act (Republic Act No. 9147), which criminalises the killing, trade, and consumption of threatened species with certain exceptions (like indigenous subsistence hunting or immediate threats to human life), with a maximum penalty of two years imprisonment and a fine of ₱20,000.[69][70][71]

Cultural significance

Further information: Snakes in mythology

The king cobra has an eminent position in the mythology and folklore of India, Bangladesh, Sri Lanka and Myanmar.[72] A ritual in Myanmar involves a king cobra and a female snake charmer. The charmer is a priestess who is usually tattooed with three pictograms and kisses the snake on the top of its head at the end of the ritual.[73] Members of the Pakokku clan tattoo themselves with ink mixed with cobra venom on their upper bodies in a weekly inoculation that they believe would protect them from the snake, though no scientific evidence supports this.[36][74] It is regarded as the national reptile of India.[75] In India, the king cobra is believed to possess exceptional memory; according to a myth, the killer of a king cobra stays in the eyes of the snake as an image, which is later picked up by the snake's partner and used to hunt down the killer for revenge. Because of this myth, whenever a cobra is killed especially in India, the head, if not the entire body, is either crushed or burned to destroy the eyes completely.[76]

References

  1. ^ a b c d e Stuart, B.; Wogan, G.; Grismer, L.; Auliya, M.; Inger, R.F.; Lilley, R.; Chan-Ard, T.; Thy, N.; Nguyen, T.Q.; Srinivasulu, C.; Jelić, D. (2012). "Ophiophagus hannah". IUCN Red List of Threatened Species. 2012: e.T177540A1491874. doi:10.2305/IUCN.UK.2012-1.RLTS.T177540A1491874.en. Retrieved 20 November 2021.
  2. ^ a b c d e Mehrtens, J. (1987). "King Cobra, Hamadryad (Ophiophagus hannah)". Living Snakes of the World. New York: Sterling. p. 263–. ISBN 0-8069-6461-8.
  3. ^ Lillywhite, Harvey B. (2014). How Snakes Work: Structure, Function and Behavior of the World's Snakes. New York: Oxford University Press. p. 241. ISBN 978-0-19-538037-8.
  4. ^ a b c Cantor, T. E. (1836). "Sketch of an undescribed hooded serpent, with fangs and maxillar teeth". Asiatic Researches. 19: 87–93.
  5. ^ a b c d e Das, I.; Shankar, P. G.; Swamy, P.; Williams, R. C.; Lalremsanga, H. T.; Prashanth, P.; Sahoo, G.; Vijayakumar, S. P.; Höglund, J.; Shanker, K.; Dutta, S. K.; Ganesh, S. R.; Wüster, W. (2024). "Taxonomic revision of the king cobra Ophiophagus hannah (Cantor, 1836) species complex (Reptilia: Serpentes: Elapidae), with the description of two new species". European Journal of Taxonomy (961): 1–51. doi:10.5852/ejt.2024.961.2681.
  6. ^ Günther, A. C. L. G. (1864). "Ophiophagus, Gthr.". The Reptiles of British India. London: Ray Society. pp. 340–342.
  7. ^ O'Shea, M. (2005). Venomous Snakes of the World. New Jersey, USA: Princeton University Press. pp. 96–97. ISBN 978-0-691-12436-0.
  8. ^ Bogert, C. M. (1945). "Hamadryas Preoccupied for the King Cobra". Copeia. 1945 (1): 47. doi:10.2307/1438180. JSTOR 1438180.
  9. ^ Cantor, T. E. (1838). "A notice of the Hamadryas, a genus of hooded serpent with poisonous fangs and maxillary teeth". Proceedings of the Zoological Society of London. 6: 72–75. Archived from the original on 14 October 2019. Retrieved 14 October 2019.
  10. ^ Elliot, W. (1840). "Description of a New Species of Naga, or Cobra de Capello". Madras Journal of Literature and Science. 11: 39–41.
  11. ^ Günther, A. (1858). Catalogue of colubrine snakes in the collection of the British Museum. London: Printed by order of the Trustees. p. 219.
  12. ^ Van Hasselt, A. W. M. (1882). "Eene Monster-Naja". Verslagen en Mededeelingen der Koninklijke Akademie van Wetenschappen. 2. 17: 140–143.
  13. ^ Schlegel, H. (1837). "Le Naja Bongare. N. bungarus". Essai sur la physionomie des serpens. Amsterdam: Schonekat. p. 476.
  14. ^ Slowinski, J. B.; Keogh, J. S. (2000). "Phylogenetic Relationships of Elapid Snakes Based on Cytochrome b mtDNA Sequences" (PDF). Molecular Phylogenetics and Evolution. 15 (1): 157–164. Bibcode:2000MolPE..15..157S. doi:10.1006/mpev.1999.0725. PMID 10764543. Archived (PDF) from the original on 14 March 2019. Retrieved 14 October 2019.
  15. ^ Figueroa, A.; McKelvy, A. D.; Grismer, L. L.; Bell, C. D.; Lailvaux, S. P. (2016). "A species-level phylogeny of extant snakes with description of a new colubrid subfamily and genus". PLOS ONE. 11 (9): e0161070. Bibcode:2016PLoSO..1161070F. doi:10.1371/journal.pone.0161070. PMC 5014348. PMID 27603205.
  16. ^ Suntrarachun, S.; Chanhome, L.; Sumontha, M. (2014). "Phylogenetic analysis of the king cobra, Ophiophagus hannah in Thailand based on mitochondrial DNA sequences". Asian Biomedicine. 8 (2): 269–274. doi:10.5372/1905-7415.0802.289.
  17. ^ Smith, M. A. (1943). "Naja hannah. Hamadryad, King Cobra". The Fauna of British India, Ceylon and Burma, including the whole of the Indo-Chinese Subregion. Vol. Reptilia and Amphibia. III. – Serpentes. London: Taylor and Francis. pp. 436–438.
  18. ^ a b Chanhome, L.; Cox, M. J.; Vasaruchapong, T.; Chaiyabutr, N.; Sitprija, V. (2011). "Characterization of venomous snakes of Thailand". Asian Biomedicine. 5 (3): 311–328. doi:10.5372/1905-7415.0503.043 (inactive 1 November 2024).{{cite journal}}: CS1 maint: DOI inactive as of November 2024 (link)
  19. ^ Martin, D. L. (2012). "Identification of Reptile Skin Products Using Scale Morphology". In J. E. Huffman, J. R. Wallace (ed.). Wildlife Forensics: Methods and Applications. Oxford: Wiley. pp. 161–199. ISBN 978-1-119-95429-3. Archived from the original on 10 February 2023. Retrieved 4 October 2020.
  20. ^ a b Shankar, P. G.; Ganesh, S. R.; Whitaker, R.; Prashanth, P. (2013). "King Cobra Ophiophagus hannah (Cantor, 1836) encounters in human-modified rainforests of the Western Ghats, India". Hamadryad (36): 62–68.
  21. ^ Burton, R. W. (1950). "The record hamadryad or king cobra [Naja hannah (Cantor)] and lengths and weights of large specimens". The Journal of the Bombay Natural History Society. 49: 561–562.
  22. ^ a b O'Shea, M. (2008). Venomous snakes of the world. London, Cape Town, Sydney, Auckland: Bloomsbury. ISBN 978-1-84773-086-2.
  23. ^ Singh, A.; Joshi, R. (2016). "A first record of the King Cobra Ophiophagus hannah (Reptilia: Squamata: Elapidae) nest from Garhwal Himalaya, northern India". Zoo's Print. 31: 9–11.
  24. ^ Dolia, J. (2018). "Notes on the distribution and natural history of the King Cobra (Ophiophagus hannah Cantor, 1836) from the Kumaon Hills of Uttarakhand, India". Herpetology Notes. 11: 217–222. Archived from the original on 16 October 2019. Retrieved 16 October 2019.
  25. ^ Kanaujia, A.; Kumar, A.; Kumar, A. (2017). "Herpetofauna of Uttar Pradesh, India". Biological Forum. 9 (1): 118–130.
  26. ^ a b c Wallach, V.; Williams, K.L.; Boundy, J. (2014). Snakes of the world: A catalogue of living and extinct species. Florida: CRC Press, Taylor and Francis Group. pp. 507–508. ISBN 978-1-4822-0848-1.
  27. ^ Bashir, T.; Poudyal, K.; Bhattacharya, T.; Sathyakumar, S.; Subba, J. B. (2010). "Sighting of King Cobra Ophiophagus hannah in Sikkim, India: a new altitude record for the northeast". Journal of Threatened Taxa. 2 (6): 990–991. doi:10.11609/JoTT.o2438.990-1.
  28. ^ Murthy, K.L.N.; Murthy, K.V.R. (2012). "Sightings of King Cobra Ophiophagus hannah in northern coastal Andhra Pradesh". Reptile Rap. 14: 29–32.
  29. ^ Yadav, O. V.; Yankanchi, S. R. (2015). "Occurence [sic] of Ophiophagus hannah Cantor, 1836 (Squamata, Elapidae) in Tillari, Maharashtra, India". Herpetology Notes. 8: 493–494. Archived from the original on 10 February 2023. Retrieved 22 April 2022.
  30. ^ Palot, M. J. (2015). "A checklist of reptiles of Kerala, India". Journal of Threatened Taxa. 7 (13): 8010–8022. doi:10.11609/jott.2002.7.13.8010-8022.
  31. ^ Manchi, S.; Sankaran, R. (2009). "Predators of swiftlets and their nests in the Andaman and Nicobar Islands". Indian Birds. 5 (4): 118–120.
  32. ^ Marshall, B.M.; Strine, C.T.; Jones, M.D.; Theodorou, A.; Amber, E.; Waengsothorn, S.; Suwanwaree, P.; Goode, M. (2018). "Hits close to home: repeated persecution of King Cobras (Ophiophagus hannah) in northeastern Thailand". Tropical Conservation Science. 11: 1–14. doi:10.1177/1940082918818401. hdl:10150/632917.
  33. ^ a b Wall, F. (1924). "The Hamadryad or King Cobra Naja hannah (Cantor)". The Journal of the Bombay Natural History Society. 30 (1): 189–195.
  34. ^ Bhaisare, D.; Ramanuj, V.; Shankar, P. G.; Vittala, M.; Goode, M.; Whitaker, R. (2010). "Observations on a wild King Cobra (Ophiophagus hannah), with emphasis on foraging and diet". IRCF Reptiles & Amphibians. 17 (2): 95–102. doi:10.17161/randa.v17i2.16088. S2CID 257621424.
  35. ^ Kurniawan, A.; Lee, G.; bin Tohed, N.; Low, M.-R. (2018). "King cobra feeding on a monitor lizard at night" (PDF). Singapore Biodiversity Records. 2018: 63. Archived (PDF) from the original on 16 October 2019. Retrieved 16 October 2019.
  36. ^ a b Coborn, J. (1991). The Atlas of Snakes of the World. TFH Publications. pp. 30, 452. ISBN 978-0-86622-749-0.
  37. ^ Tweedie, M. W. F. (1983). The Snakes of Malaya. Singapore National Printers. p. 142. OCLC 686366097.
  38. ^ Greene, H. W. (1997). "Antipredator tactics of snakes". Snakes: The Evolution of Mystery in Nature. California, USA: University of California Press. pp. 103–111. ISBN 0-520-22487-6. Archived from the original on 10 February 2023. Retrieved 4 October 2020.
  39. ^ Lim, K. K. P.; Leong, T. M.; Lim, L. K. (2011). "The king cobra, Ophiophagus hannah (Cantor) in Singapore (Reptilia: Squamata: Elapidae)" (PDF). Nature in Singapore. 4: 143–156. Archived (PDF) from the original on 16 October 2019. Retrieved 16 October 2019.
  40. ^ a b c d e f Davidson, T. "Immediate First Aid". University of California, San Diego. Archived from the original on 30 June 2010. Retrieved 24 September 2011.
  41. ^ Young, B. A. (1991). "Morphological basis of "growling" in the king cobra, Ophiophagus hannah". Journal of Experimental Zoology. 260 (3): 275–287. doi:10.1002/jez.1402600302. PMID 1744612.
  42. ^ a b Whitaker, N.; Shankar, P. G.; Whitaker, R. (2013). "Nesting ecology of the King Cobra (Ophiophagus hannah) in India" (PDF). Hamadryad. 36 (2): 101–107.[dead link‍]
  43. ^ Hrima, V. L.; Sailo, V. H.; Fanai, Z.; Lalronunga, S.; Lalrinchhana, C. (2014). "Nesting ecology of the King Cobra, Ophiophagus hannah, (Reptilia: Squamata: Elapidae) in Aizawl District, Mizoram, India". In Lalnuntluanga; Zothanzama, J.; Lalramliana; Lalduhthlana; Lalremsanga, H. T. (eds.). Issues and Trends of Wildlife Conservation in Northeast India. Aizawl: Mizo Academy of Sciences. pp. 268–274. ISBN 9788192432175.
  44. ^ a b Card DC, Vonk FJ, Smalbrugge S, Casewell NR, Wüster W, Castoe TA, Schuett GW, Booth W (2021). "Genome-wide data implicate terminal fusion automixis in king cobra facultative parthenogenesis". Sci Rep. 11 (1): 7271. doi:10.1038/s41598-021-86373-1. PMC 8012631. PMID 33790309.
  45. ^ "King Cobra". National Geographic Society. 2010. Archived from the original on 22 February 2022. Retrieved 30 October 2022.
  46. ^ Li, J.; Zhang, H.; Liu, J.; Xu, K. (2006). "Novel genes encoding six kinds of three-finger toxins in Ophiophagus hannah (king cobra) and function characterization of two recombinant long-chain neurotoxins". Biochemical Journal. 398 (2): 233–342. doi:10.1042/BJ20060004. PMC 1550305. PMID 16689684.
  47. ^ Roy, A.; Zhou, X.; Chong, M. Z.; d'Hoedt, D.; Foo, C. S.; Rajagopalan, N.; Nirthanan, S.; Bertrand, D.; Sivaraman, J.; Kini, R. M. (2010). "Structural and Functional Characterization of a Novel Homodimeric Three-finger Neurotoxin from the Venom of Ophiophagus hannah (King Cobra)". The Journal of Biological Chemistry. 285 (11): 8302–8315. doi:10.1074/jbc.M109.074161. PMC 2832981. PMID 20071329.
  48. ^ Chang, L.-S.; Liou, J.-C.; Lin, S.-R.; Huang, H.-B. (2002). "Purification and characterization of a neurotoxin from the venom of Ophiophagus hannah (king cobra)". Biochemical and Biophysical Research Communications. 294 (3): 574–578. doi:10.1016/S0006-291X(02)00518-1. PMID 12056805.
  49. ^ He, Y. Y.; Lee, W. H.; Zhang, Y. (2004). "Cloning and purification of alpha-neurotoxins from king cobra (Ophiophagus hannah)". Toxicon. 44 (3): 295–303. Bibcode:2004Txcn...44..295H. doi:10.1016/j.toxicon.2004.06.003. PMID 15302536.
  50. ^ Rajagopalan, N.; Pung, Y. F.; Zhu, Y. Z.; Wong, P. T. H.; Kumar, P. P.; Kini, R. M. (2007). "β-Cardiotoxin: A new three-finger toxin from Ophiophagus hannah (King Cobra) venom with beta-blocker activity". The FASEB Journal. 21 (13): 3685–3695. doi:10.1096/fj.07-8658com. PMID 17616557. S2CID 21235585.
  51. ^ Bianca Op den Brouw; Manuel Fernandez-Rojo; Tom Charlton; Bryan G. Fry; Maria P. Ikonomopoulou (2023). "Malaysian and Chinese King Cobra Venom Cytotoxicity in Melanoma and Neonatal Foreskin Fibroblasts Is Mediated by Age and Geography". Toxins. 15 (9): 574–578. doi:10.3390/toxins15090549. PMC 10534572. PMID 12056805.
  52. ^ a b Tan, C. H.; Tan, K. Y.; Fung, S. Y.; Tan, N. H. (2015). "Venom-gland transcriptome and venom proteome of the Malaysian king cobra (Ophiophagus hannah)". BMC Genomics. 16 (1): 687. doi:10.1186/s12864-015-1828-2. PMC 4566206. PMID 26358635.
  53. ^ Petras, D.; Heiss, P.; Süssmuth, R. D.; Calvete, J. J. (2015). "Venom proteomics of Indonesian King Cobra, Ophiophagus hannah: Integrating top-down and bottom-up approaches". Journal of Proteome Research. 14 (6): 2539–2556. doi:10.1021/acs.jproteome.5b00305. PMID 25896403.
  54. ^ Liu, C.-C.; You, C.-H.; Wang, P.-J.; Yu, J.-S.; Huang, G.-J.; Liu, C.-H.; Hsieh, W.-C.; Lin, C.-C. (2017). "Analysis of the efficacy of Taiwanese freeze-dried neurotoxic antivenom against Naja kaouthia, Naja siamensis and Ophiophagus hannah through proteomics and animal model approaches". PLOS Neglected Tropical Diseases. 11 (12): e0006138. doi:10.1371/journal.pntd.0006138. PMC 5747474. PMID 29244815.
  55. ^ Vonk, F. J.; Casewell, N. R.; Henkel, C. V.; Heimberg, A. M.; Jansen, H. J.; McCleary, Ryan J. R.; Kerkkamp, Harald M. E.; Vos, Rutger A.; Guerreiro, I.; Calvete, J. J.; Wüster, W. (2013). "The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system". Proceedings of the National Academy of Sciences. 110 (51): 20651–20656. Bibcode:2013PNAS..11020651V. doi:10.1073/pnas.1314702110. PMC 3870661. PMID 24297900.
  56. ^ a b Tan, N.H.; Saifuddin, M.N. (1990). "solation and characterization of a hemorrhagin from the venom of Ophiophagus hannah (king cobra)". Toxicon. 28 (4): 385–392. Bibcode:1990Txcn...28..385T. doi:10.1016/0041-0101(90)90076-j. PMID 2190359.
  57. ^ Pung, Y. F.; Kumar, S. V.; Rajagopalan, N.; Fry, B. G.; Kumar, P. P.; Kini, R. M. (2006). "Ohanin, a novel protein from king cobra venom: Its cDNA and genomic organization". Gene. 371 (2): 246–256. doi:10.1016/j.gene.2005.12.002. PMID 16472942.
  58. ^ a b Tin-Myint; Rai-Mra; Maung-Chit; Tun-Pe; Warrell, D. (1991). "Bites by the king cobra (Ophiophagus hannah) in Myanmar: Successful treatment of severe neurotoxic envenoming". The Quarterly Journal of Medicine. 80 (293): 751–762. doi:10.1093/oxfordjournals.qjmed.a068624. PMID 1754675.
  59. ^ Whitaker, R.; Whitaker, S. (2012). "Venom, antivenom production and the medically important snakes of India" (PDF). Current Science. 103 (6): 635–643. Archived (PDF) from the original on 16 October 2019. Retrieved 16 October 2019.
  60. ^ Leong, P. K.; Sim, S. M.; Fung, S. Y.; Sumana, K.; Sitprija, V.; Tan, N. H. (2012). "Cross Neutralization of Afro-Asian Cobra and Asian Krait Venoms by a Thai Polyvalent Snake Antivenom (Neuro Polyvalent Snake Antivenom)". PLOS Neglected Tropical Diseases. 6 (6): e1672. doi:10.1371/journal.pntd.0001672. PMC 3367981. PMID 22679522.
  61. ^ Ernst, C. H.; Evelyn, M. (2011). "Treatment of envenomation by reptiles". Venomous Reptiles of the United States, Canada, and Northern Mexico. Vol. 1: Heloderma, Micruroides, Micrurus, Pelamis, Agkistrodon, Sistrurus. Baltimore: Johns Hopkins University Press. pp. 33–46. ISBN 978-0-8018-9875-4.
  62. ^ Salama, R.; Sattayasai, J.; Gande, A. K.; Sattayasai, N.; Davis, M.; Lattmann, E. (2012). "Identification and evaluation of agents isolated from traditionally used herbs against Ophiophagus hannah venom". Drug Discoveries & Therapeutics. 6 (1): 18–23. PMID 22460424.
  63. ^ a b Thomas, S.; Griessel, E. (1999). "LD50 (Archived)". Archived from the original on 1 February 2012.
  64. ^ Ganthavorn, S. (1969). "Toxicities of Thailand snake venoms and neutralization capacity of antivenin". Toxicon. 7 (3): 239–241. Bibcode:1969Txcn....7..239G. doi:10.1016/0041-0101(69)90012-9. PMID 5358069.
  65. ^ Broad, A. J.; Sutherland, S. K.; Coulter, A. R. (1979). "The lethality in mice of dangerous Australian and other snake venom" (PDF). Toxicon. 17 (6): 661–664. Bibcode:1979Txcn...17..661B. doi:10.1016/0041-0101(79)90245-9. PMID 524395. Archived (PDF) from the original on 31 March 2022. Retrieved 14 October 2019.
  66. ^ Engelmann, W.-E. (1981). Snakes: Biology, Behavior, and Relationship to Man. Leipzig; English version NY, USA: Leipzig Publishing; English version published by Exeter Books (1982). p. 222. ISBN 0-89673-110-3.
  67. ^ Handbook of clinical toxicology of animal venoms and poisons. Vol. 236. USA: CRC Press. 1995. ISBN 0-8493-4489-1.
  68. ^ Sivakumar, B. (2012). "King cobra under threat, put on red list". The Times of India. Archived from the original on 1 February 2013.
  69. ^ "Republic Act No. 9147". Official Gazette. Republic of the Philippines. Archived from the original on 27 September 2023. Retrieved 26 March 2023.
  70. ^ "How venomous is a king cobra and what should you do if you see one? Kuya Kim answers". GMA News Online. 26 March 2023. Retrieved 26 March 2023.
  71. ^ Garcia, Danilo (23 December 2021). "5 King Cobra nakumpiska sa NBI entrapment". Pilipino Star Ngayon. Retrieved 26 March 2023.
  72. ^ Minton, S.A. Jr.; Minton, M.R. (1980). Venomous reptiles. New York: Charles Scribner's Sons. ISBN 978-0-684-16626-1.
  73. ^ Platt, S.G.; Ko, W.K.; Rainwater, T.R. (2012). "On the Cobra Cults of Myanmar (Burma)". Chicago Herpetological Society. 47 (2): 17–20.
  74. ^ Murphy, J. C. (2010). Secrets of the Snake Charmer: Snakes in the 21st Century. iUniverse. ISBN 978-1-4502-2127-6.
  75. ^ "King Cobra – National Reptile of India". indiamapped. Archived from the original on 17 January 2018. Retrieved 17 January 2018.
  76. ^ "King Cobra The King of Venomous Snakes". aboutanimals.com. aboutanimals. Retrieved 5 November 2024.
Wikimedia Commons has media related to:
Ophiophagus hannah (category)
Wikispecies has information related to Ophiophagus hannah.

Read other articles:

Argiope anasuja

Argiope anasuja Klasifikasi ilmiah Kerajaan: Animalia Filum: Arthropoda Kelas: Arachnida Ordo: Araneae Famili: Araneidae Genus: Argiope Spesies: Argiope anasuja Nama binomial Argiope anasujaThorell, 1887 Argiope anasuja adalah spesies laba-laba yang tergolong famili Araneidae. Spesies ini juga merupakan bagian dari genus Argiope dan ordo Araneae. Nama ilmiah dari spesies ini pertama kali diterbitkan pada tahun 1887 oleh Thorell. Laba-laba ini biasanya banyak ditemui di Pakistan hingga Maldiv...

 

 

Abdurrahman as-Sudais

Biografi ini tidak memiliki sumber tepercaya sehingga isinya tidak dapat dipastikan. Bantu memperbaiki artikel ini dengan menambahkan sumber tepercaya. Materi kontroversial atau trivial yang sumbernya tidak memadai atau tidak bisa dipercaya harus segera dihapus.Cari sumber: Abdurrahman as-Sudais – berita · surat kabar · buku · cendekiawan · JSTOR (Pelajari cara dan kapan saatnya untuk menghapus pesan templat ini) Abdurrahman as-SudaisNama dalam bahasa ...

 

 

Aura

Untuk kegunaan lain, lihat Aura (disambiguasi). Perangkat untuk mendeteksi aura melalui telapak tangan Dalam penggunaan bahasa sementara ada kata Aura, tetapi maknanya bisa sangat berbeda. Bagi banyak orang, Aura hanya cahaya dari manusia. Bagi para ilmuwan, itu adalah, pancaran energi yang sudah ada, yang mengelilingi makhluk hidup. Aura ini berbentuk radiasi warna halus yang mengelilingi makhluk hidup. Setiap warna menandakan getaran tertentu yang memiliki arti yang berbeda.[1] Seja...

Первородный грех

Об экономическом термине см. Первородный грех (экономика). ХристианствоБиблия Ветхий Завет Новый Завет Евангелие Десять заповедей Нагорная проповедь Апокрифы Бог, Троица Бог Отец Иисус Христос Святой Дух История христианства Апостолы Хронология христианства Ран�...

 

 

Lovers' Concerto (film)

Halaman ini berisi artikel tentang film Korea. Untuk lagu the Toys', lihat A Lover's Concerto. Lovers' ConcertoNama lainHangul연애소설 Hanja戀愛小說 Alih Aksara yang DisempurnakanYeonae SoseolMcCune–ReischauerYǒnae Sosǒl SutradaraLee HanProduserHang Sang-guDitulis olehLee HanPemeranCha Tae-hyunLee Eun-juSon Ye-jinPenata musikKim Sang-heonSinematograferJin Young-hwanPenyuntingKim HyeonDistributorKorea PicturesTanggal rilis 13 September 2002 (2002-09-13)[1] ...

 

 

مينتيلوغلي

مينتيلوغلي   تقسيم إداري البلد اليونان  [1] خصائص جغرافية إحداثيات 38°11′00″N 21°42′00″E / 38.18333333°N 21.7°E / 38.18333333; 21.7   الارتفاع 46 متر  السكان التعداد السكاني 2104 (resident population of Greece) (2021)1471 (resident population of Greece) (1991)1720 (resident population of Greece) (2001)2120 (resident population of Greece) (2011)...

The Savage (1952 film)

1952 film by George Marshall The SavageTheatrical release posterDirected byGeorge MarshallScreenplay bySydney BoehmBased onThe Renegadeby L. L. ForemanProduced byMel EpsteinStarring Charlton Heston Susan Morrow Peter Hansen CinematographyJohn F. SeitzEdited byArthur P. SchmidtMusic byPaul SawtellProductioncompanyParamount PicturesDistributed byParamount PicturesRelease date September 1952 (1952-09) Running time95 minutesCountryUnited StatesLanguageEnglish The Savage is a 1952 Americ...

 

 

Polder

Polder Polder adalah sebidang tanah yang rendah, dikelilingi oleh embankment / timbunan atau tanggul yang membentuk semacam kesatuan hidrologis buatan, yang berarti tidak ada kontak dengan air dari daerah luar selain yang dialirkan melalui perangkat manual. Contoh Contoh polder: tanah yang direklamasi dari badan air misalnya danau yang dikeringkan dan dijadikan kawasan tertentu. dataran banjir yang dipisahkan dari laut atau sungai menggunakan tanggul, rawa yang dikelilingi air yang kemudian d...

 

 

B

  此條目介紹的是拉丁字母中的第2个字母。关于其他用法，请见「B (消歧义)」。   提示：此条目页的主题不是希腊字母Β、西里尔字母В、Б、Ъ、Ь或德语字母ẞ、ß。 BB b(见下)用法書寫系統拉丁字母英文字母ISO基本拉丁字母（英语：ISO basic Latin alphabet）类型全音素文字相关所属語言拉丁语读音方法 [b][p][ɓ](适应变体)Unicode编码U+0042, U+0062字母顺位2数值 2歷史發...

China at the 2000 Summer Olympics

Sporting event delegationChina at the2000 Summer OlympicsIOC codeCHNNOCChinese Olympic CommitteeWebsitewww.olympic.cn (in Chinese and English)in SydneyCompetitors271 (91 men and 180 women) in 28 sportsFlag bearer Liu YudongMedalsRanked 3rd Gold 28 Silver 16 Bronze 14 Total 58 Summer Olympics appearances (overview)19521956–198019841988199219962000200420082012201620202024Other related appearances Republic of China (1924–1948) The People's Republic of China competed at the 20...

 

 

Feldheim Publishers

American Orthodox Jewish publisher of Torah books and literatureFeldheim PublishersParent companyPhillip Feldheim, Inc.StatusActiveFounded1939FounderPhillip FeldheimCountry of originUnited StatesHeadquarters locationSpring Valley, New YorkKey peopleYitzchak Feldheim, presidentNonfiction topicsJewish law, Torah, Talmud, Jewish lifestyle, Shabbat and Jewish holidays, Jewish history, biography, kosher cookbooksOfficial websitewww.feldheim.com Feldheim Publishers (or Feldheim) is an American Orth...

 

 

2013 aux États-Unis

Chronologies Chronologie des États-Unis 2010 2011 2012  2013  2014 2015 2016Décennies aux États-Unis :1980 1990 2000  2010  2020 2030 2040 Chronologie dans le monde 2010 2011 2012  2013  2014 2015 2016Décennies :1980 1990 2000  2010  2020 2030 2040Siècles :XIXe XXe  XXIe  XXIIe XXIIIeMillénaires :Ier IIe  IIIe  Chronologies géographiques Afrique Afrique du Sud, Algérie, Angola, Bénin, Botswana, Burkina F...

コルク

この記事は検証可能な参考文献や出典が全く示されていないか、不十分です。出典を追加して記事の信頼性向上にご協力ください。（このテンプレートの使い方）出典検索?: コルク – ニュース · 書籍 · スカラー · CiNii · J-STAGE · NDL · dlib.jp · ジャパンサーチ · TWL（2017年4月） コルクを打ち抜いて作った瓶の栓 コルク（木栓、�...

 

 

Yahoo! 360°

This article relies excessively on references to primary sources. Please improve this article by adding secondary or tertiary sources. Find sources: Yahoo! 360° – news · newspapers · books · scholar · JSTOR (April 2008) (Learn how and when to remove this message) Yahoo! 360°Yahoo! PulseType of siteSocial network serviceOwnerYahoo!Created byYahoo!URL360.yahoo.compulse.yahoo.comCommercialYesRegistrationYahoo! accountLaunchedMarch 16, 2005...

 

 

Steve Shurtleff

American politician Steve ShurtleffSpeaker of the New Hampshire House of RepresentativesIn officeDecember 5, 2018 – December 2, 2020DeputyKaren EbelPreceded byGene ChandlerSucceeded byDick HinchMinority Leader of the New Hampshire House of RepresentativesIn officeDecember 4, 2014 – December 5, 2018DeputyCindy RosenwaldPreceded byGene ChandlerSucceeded byDick HinchMajority Leader of the New Hampshire House of RepresentativesIn officeDecember 2012 – December 4, ...

1900年美國總統選舉

1900年美國總統選舉 ← 1896 1900年11月6日 1904 → 447張選舉人票獲勝需224張選舉人票投票率73.2%[1] ▼ 6.1 %   获提名人 威廉·麥金利 威廉·詹寧斯·布賴恩 政党 共和黨 民主党 家鄉州 俄亥俄州 內布拉斯加州 竞选搭档 西奧多·羅斯福 阿德萊·史蒂文森一世 选举人票 292 155 胜出州/省 28 17 民選得票 7,228,864 6,370,932 得票率 51.6% 45.5% 總統選舉結果地圖，紅色代表�...

 

 

Index of Missouri-related articles

The location of the state of Missouri in the United States of America Main article: Missouri See also: Outline of Missouri The following is an alphabetical list of articles related to the U.S. state of Missouri. Contents 0–9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0–9 An enlargeable map of the state of Missouri .mo.us – Internet second-level domain for the state of Missouri 24th state to join the United States of America A Adjacent states: (one of only two states with eight...

 

 

Theatre of ancient Rome

Theatrical genre Roman mosaic depicting actors and an aulos player (House of the Tragic Poet, Pompeii). The architectural form of theatre in Rome has been linked to later, more well-known examples from the 1st century BC to the 3rd Century AD.[1] The theatre of ancient Rome referred to a period of time in which theatrical practice and performance took place in Rome. The tradition has been linked back even further to the 4th century BC, following the state’s transition from monarchy ...

Budleigh Salterton

Town in Devon, England Human settlement in EnglandBudleigh SaltertonThe seafront looking west towards Exmouth. The red cliffs are around 250 million years old.Budleigh SaltertonLocation within DevonPopulation6,575 (2012)OS grid referenceSY066818DistrictEast DevonShire countyDevonRegionSouth WestCountryEnglandSovereign stateUnited KingdomPost townBUDLEIGH SALTERTONPostcode districtEX9Dialling code01395PoliceDevon and CornwallFireDevon and SomersetAmbulanceSou...

 

 

Enzo Cilenti

British actor (born 1974) Enzo CilentiCilenti at the premiere of Free Fire at Toronto Film Festival in 2016BornVincenzo Leonardo Cilenti (1974-08-08) 8 August 1974 (age 49)Bradford, West Yorkshire, EnglandYears active1998–presentSpouse Sienna Guillory ​(m. 2002)​Children2 Vincenzo Leonardo Enzo Cilenti (born 8 August 1974) is a British actor, known for his roles in works such as The Theory of Everything, Jonathan Strange & Mr Norrell, and Game of T...