General Barnes may refer to:

• Edward Barnes (British Army officer) (1776–1838), British Army lieutenant general
• Gladeon M. Barnes (1887–1961), U.S. Army major general
• James Barnes (general) (1801–1869), Union Army brigadier general and brevet major general
• Joseph Barnes (American physician) (1817–1883), Union Army brigadier general and brevet major general, 12th Surgeon General of the United States Army
• Reginald Barnes (1871–1946), British Army major general

• Alfred Smith Barnes (1817–1888), American publisher and philanthropist known as "the General"
• Attorney General Barnes (disambiguation)

This disambiguation page lists articles associated with the title General Barnes.
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