Gamma-curcumene synthase

γ-curcumene synthase
Identifiers
EC no.4.2.3.94
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

γ-Curcumene synthase (EC 4.2.3.94, PatTpsA (gene)) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, γ-curcumene-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate γ-curcumene + diphosphate

This enzyme is one of five sesquiterpenoid synthases in Pogostemon cablin (patchouli).

References

  1. ^ Deguerry F, Pastore L, Wu S, Clark A, Chappell J, Schalk M (October 2006). "The diverse sesquiterpene profile of patchouli, Pogostemon cablin, is correlated with a limited number of sesquiterpene synthases". Archives of Biochemistry and Biophysics. 454 (2): 123–36. doi:10.1016/j.abb.2006.08.006. PMID 16970904.