Ent-isokaurene synthase

ent-isokaurene synthase
Identifiers
EC no.4.2.3.103
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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PMCarticles
PubMedarticles
NCBIproteins

ent-Isokaurene synthase (EC 4.2.3.103, OsKSL5i, OsKSL6) is an enzyme with systematic name ent-copalyl-diphosphate diphosphate-lyase (cyclizing, ent-isokaurene-forming).[1][2] This enzyme catalyses the following chemical reaction

ent-copalyl diphosphate ent-isokaurene + diphosphate

Two enzymes of the rice sub-species Oryza sativa ssp. indica, OsKSL5 and OsKSL6, produce ent-isokaurene.

References

  1. ^ Xu M, Wilderman PR, Morrone D, Xu J, Roy A, Margis-Pinheiro M, Upadhyaya NM, Coates RM, Peters RJ (February 2007). "Functional characterization of the rice kaurene synthase-like gene family". Phytochemistry. 68 (3): 312–26. Bibcode:2007PChem..68..312X. doi:10.1016/j.phytochem.2006.10.016. PMID 17141283.
  2. ^ Xu M, Wilderman PR, Peters RJ (May 2007). "Following evolution's lead to a single residue switch for diterpene synthase product outcome". Proceedings of the National Academy of Sciences of the United States of America. 104 (18): 7397–401. Bibcode:2007PNAS..104.7397X. doi:10.1073/pnas.0611454104. PMC 1855280. PMID 17456599.


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