Protein-coding gene in the species Homo sapiens
Dynein light chain 2, cytoplasmic is a protein that in humans is encoded by the DYNLL2 gene .[ 5] [ 6]
Interactions
DYNLL2 has been shown to interact with DLG4 ,[ 7] C12orf40 ,[ 8] DLGAP1 ,[ 7] MYO5A [ 7] [ 9] BMF .[ 9] [ 10]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000264364 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020483 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, et al. (November 2005). "Cytoplasmic dynein nomenclature" . The Journal of Cell Biology . 171 (3): 411– 413. doi :10.1083/jcb.200508078 . PMC 2171247 PMID 16260502 . ^ "Entrez Gene: DYNLL2 dynein, light chain, LC8-type 2" .^ a b c Naisbitt S, Valtschanoff J, Allison DW, Sala C, Kim E, Craig AM, et al. (June 2000). "Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein" . The Journal of Neuroscience . 20 (12): 4524– 4534. doi :10.1523/JNEUROSCI.20-12-04524.2000 PMC 6772433 PMID 10844022 . ^ Rolland T, Taşan M, Charloteaux B, Pevzner SJ, Zhong Q, Sahni N, et al. (November 2014). "A proteome-scale map of the human interactome network" . Cell . 159 (5): 1212– 1226. doi :10.1016/j.cell.2014.10.050 . PMC 4266588 PMID 25416956 . ^ a b Puthalakath H, Villunger A, O'Reilly LA, Beaumont JG, Coultas L, Cheney RE, et al. (September 2001). "Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis". Science . 293 (5536): 1829– 1832. Bibcode :2001Sci...293.1829P . doi :10.1126/science.1062257 . PMID 11546872 . S2CID 5638023 . ^ Day CL, Puthalakath H, Skea G, Strasser A, Barsukov I, Lian LY, et al. (February 2004). "Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands" . The Biochemical Journal . 377 (Pt 3): 597– 605. doi :10.1042/BJ20031251 . PMC 1223895 PMID 14561217 .
Further reading
Naisbitt S, Valtschanoff J, Allison DW, Sala C, Kim E, Craig AM, et al. (June 2000). "Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein" . The Journal of Neuroscience . 20 (12): 4524– 4534. doi :10.1523/JNEUROSCI.20-12-04524.2000 PMC 6772433 PMID 10844022 . Haraguchi K, Satoh K, Yanai H, Hamada F, Kawabuchi M, Akiyama T (November 2000). "The hDLG-associated protein DAP interacts with dynein light chain and neuronal nitric oxide synthase" . Genes to Cells . 5 (11): 905– 911. doi :10.1046/j.1365-2443.2000.00374.x PMID 11122378 . S2CID 37107139 . Puthalakath H, Villunger A, O'Reilly LA, Beaumont JG, Coultas L, Cheney RE, et al. (September 2001). "Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis". Science . 293 (5536): 1829– 1832. Bibcode :2001Sci...293.1829P . doi :10.1126/science.1062257 . PMID 11546872 . S2CID 5638023 . Fuhrmann JC, Kins S, Rostaing P, El Far O, Kirsch J, Sheng M, et al. (July 2002). "Gephyrin interacts with Dynein light chains 1 and 2, components of motor protein complexes" . The Journal of Neuroscience . 22 (13): 5393– 5402. doi :10.1523/JNEUROSCI.22-13-05393.2002 PMC 6758200 PMID 12097491 . Day CL, Puthalakath H, Skea G, Strasser A, Barsukov I, Lian LY, et al. (February 2004). "Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands" . The Biochemical Journal . 377 (Pt 3): 597– 605. doi :10.1042/BJ20031251 . PMC 1223895 PMID 14561217 . Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, et al. (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173– 1178. Bibcode :2005Natur.437.1173R . doi :10.1038/nature04209 . PMID 16189514 . S2CID 4427026 .
Further reading
External links
Overview of all the structural information available in the PDB for UniProt : Q96FJ2 PDBe-KB .
PDB gallery
1cmi : STRUCTURE OF THE HUMAN PIN/LC8 DIMER WITH A BOUND PEPTIDE
1f3c : REFINED SOLUTION STRUCTURE OF 8KDA DYNEIN LIGHT CHAIN (DLC8)
1f95 : SOLUTION STRUCTURE OF DYNEIN LIGHT CHAIN 8 (DLC8) AND BIM PEPTIDE COMPLEX
1f96 : SOLUTION STRUCTURE OF DYNEIN LIGHT CHAIN 8 (DLC8) AND NNOS PEPTIDE COMPLEX
1pwj : Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of Domain Swapped Dimer Assembly
1pwk : Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of Domain Swapped Dimer Assembly
1re6 : Localisation of Dynein Light Chains 1 and 2 and their Pro-apoptotic Ligands
1rhw : The solution structure of the pH-induced monomer of dynein light chain LC8 from Drosophila
2pg1 : Structural analysis of a cytoplasmic dynein Light Chain-Intermediate Chain complex
