BESS domain

BESS
Identifiers
SymbolBESS
PfamPF02944
InterProIPR004210
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

In molecular biology, the BESS domain is a protein domain which has been named after the three proteins that originally defined the domain: BEAF (Boundary element associated factor 32),[1] Suvar(3)7 [2] and Stonewall [3]). The BESS domain is 40 amino acid residues long and is predicted to be composed of three alpha helices, as such it might be related to the myb/SANT HTH domain. The BESS domain directs a variety of protein-protein interactions, including interactions with itself, with Dorsal, and with a TBP-associated factor. It is found in a single copy in Drosophila proteins and is often associated with the MADF domain.[4][5][6]

Proteins known to contain a BESS domain include:

References

  1. ^ Zhao K, Hart CM, Laemmli UK (June 1995). "Visualization of chromosomal domains with boundary element-associated factor BEAF-32". Cell. 81 (6): 879–89. doi:10.1016/0092-8674(95)90008-X. PMID 7781065. S2CID 18999226.
  2. ^ Reuter G, Giarre M, Farah J, Gausz J, Spierer A, Spierer P (March 1990). "Dependence of position-effect variegation in Drosophila on dose of a gene encoding an unusual zinc-finger protein". Nature. 344 (6263): 219–23. Bibcode:1990Natur.344..219R. doi:10.1038/344219a0. PMID 2107402. S2CID 4321455.
  3. ^ Clark KA, McKearin DM (March 1996). "The Drosophila stonewall gene encodes a putative transcription factor essential for germ cell development". Development. 122 (3): 937–50. doi:10.1242/dev.122.3.937. PMID 8631271.
  4. ^ a b England BP, Admon A, Tjian R (January 1992). "Cloning of Drosophila transcription factor Adf-1 reveals homology to Myb oncoproteins". Proc. Natl. Acad. Sci. U.S.A. 89 (2): 683–7. Bibcode:1992PNAS...89..683E. doi:10.1073/pnas.89.2.683. PMC 48303. PMID 1731341.
  5. ^ a b Cutler G, Perry KM, Tjian R (April 1998). "Adf-1 is a nonmodular transcription factor that contains a TAF-binding Myb-like motif". Mol. Cell. Biol. 18 (4): 2252–61. doi:10.1128/MCB.18.4.2252. PMC 121473. PMID 9528796.
  6. ^ Bhaskar V, Courey AJ (October 2002). "The MADF-BESS domain factor Dip3 potentiates synergistic activation by Dorsal and Twist". Gene. 299 (1–2): 173–84. doi:10.1016/S0378-1119(02)01058-2. PMID 12459265.
  7. ^ Delattre M, Spierer A, Hulo N, Spierer P (January 2002). "A new gene in Drosophila melanogaster, Ravus, the phantom of the modifier of position-effect variegation Su(var)3-7". Int. J. Dev. Biol. 46 (1): 167–71. PMID 11902679.
This article incorporates text from the public domain Pfam and InterPro: IPR004210

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