The highway begins at AR 28 in western Scott County within the Ouachita Mountains. AR 28 runs southeast to Waldron, where it has a junction with US Highway 71 (US 71) on the city's west side. After this intersection, AR 80 continues due east as a section line road and major east–west route in the city. An intersection with US Highway 71 Business (US 71B) just south of downtown Waldron gives access to the primary commercial areas of Waldron. Continuing east, the highway serves as the western terminus for AR 248 just south of the Poteau River near the eastern city limits of Waldron. Just east of this junction, AR 80 passes the Poteau Work Center owned and operated by the United States Forest Service. East of Waldron, AR 80 enters the Ouachita National Forest, a dense pine and cypress forest. The route winds through the forest, serving as the eastern terminus of AR 250 before entering Yell County.[2]
State Road 80 (AR 80, Ark. 80, and Hwy. 80) was a state highway of 10.3 miles (16.6 km) in Washington County. The route began at the Oklahoma state line and ran east to AR 45 east of Lincoln.
^ abSystem Information and Research Division (2014). "Arkansas Road Log Database". Arkansas State Highway and Transportation Department. Archived from the original(MDB) on August 29, 2017. Retrieved March 27, 2016.
^Transportation Planning & Policy Division (October 9, 2013). General Highway Map, Scott County, Arkansas(PDF) (Map). 1:62500. Little Rock: Arkansas State Highway and Transportation Department. Archived from the original(PDF) on March 4, 2016. Retrieved July 30, 2016. {{cite map}}: |author= has generic name (help)
^Transportation Planning & Policy Division (April 3, 2014). General Highway Map, Yell County, Arkansas(PDF) (Map). 1:62500. Little Rock: Arkansas State Highway and Transportation Department. Archived from the original(PDF) on March 3, 2016. Retrieved July 24, 2016. {{cite map}}: |author= has generic name (help)