Highway 44 begins at US 165 north of Gillett. The route runs east through the unincorporated community of Tichnor, before ending at the La Grue Bayou about 12 miles (19.3 km) east. Highway 44 is very rural, and does not intersect any highways.
Snow Lake to Helena-West Helena
The route begins at Snow Lake as a continuation of Desha CR 629 and runs north. Highway 44 is almost entirely rural for the first 24 miles (39 km), intersecting the unincorporated communities of Ferguson, Mellwood and Crumrod. The route eventually intersects Highway 20 in Elaine, and intersects Highway 85 about 9.6 miles (15.4 km) farther down the road in Lake View. Highway 44 still remains incredibly rural all the way until it terminates at Highway 20 in Helena-West Helena.[4]
Marianna to Bear Creek Lake
Eastbound Highway 44 east of Marianna
The route begins at Highway 1B in Marianna and is locally known as Martin Luther King Jr. Drive in the town. Highway 44 heads east, out of the town and enters Mississippi River State Park shortly after, and into the St. Francis National Forest. The route continues to head southeast, and eventually terminates at Lee CR 239 at Bear Creek Lake.[5]
