An ardent advocate for prohibition, in 1944 Johnson was the Prohibition Party's nominee for Vice-President of the United States.[2][3] The Party, meeting in Indianapolis November 1943 originally named Floyd C. Carrier as its vice presidential candidate.[4] At the time of the nomination, Carrier was serving as general secretary for the American Temperance Society. He subsequently dropped out of the campaign because of health problems.[5] Johnson was added by the party's executive committee to replace him.[6] Johnson and Claude Watson, the party's presidential nominee, actively campaigned throughout the election cycle and were on the ballot in 27 states for the 1944 general election. They received a total of 74,758 votes.[7]