7,8-Dihydroneopterin triphosphate

7,8-Dihydroneopterin triphosphate
Names
Preferred IUPAC name
(2R,3S)-3-(2-Amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)-2,3-dihydroxypropyl tetrahydrogen triphosphate
Other names
DHNTP
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
KEGG
  • InChI=1S/C9H16N5O13P3/c10-9-13-7-5(8(17)14-9)12-3(1-11-7)6(16)4(15)2-25-29(21,22)27-30(23,24)26-28(18,19)20/h4,6,15-16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H4,10,11,13,14,17)/t4-,6+/m1/s1 checkY
    Key: DGGUVLXVLHAAGT-XINAWCOVSA-N checkY
  • InChI=1/C9H16N5O13P3/c10-9-13-7-5(8(17)14-9)12-3(1-11-7)6(16)4(15)2-25-29(21,22)27-30(23,24)26-28(18,19)20/h4,6,15-16H,1-2H2,(H,21,22)(H,23,24)(H2,18,19,20)(H4,10,11,13,14,17)/t4-,6+/m1/s1
    Key: DGGUVLXVLHAAGT-XINAWCOVBB
  • O=C1C2=C(NCC([C@@H]([C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O)O)=N2)NC(N)=N1
  • O=P(O)(O)OP(=O)(O)OP(=O)(O)OC[C@@H](O)[C@@H](O)C/1=N/C=2C(=O)\N=C(/NC=2NC\1)N
Properties
C9H16N5O13P3
Molar mass 495.170 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

7,8-Dihydroneopterin triphosphate (DHNTP) is an intermediate in tetrahydrobiopterin biosynthesis. It is transformed by 6-pyruvoyltetrahydropterin synthase into 6-pyruvoyl-tetrahydropterin.[1] It is also used in the Queuosine/Archeosine Pathway.[citation needed]

Synonyms

  • Dihydroneopterin Triphosphate[2]
  • 7,8-dihydroneopterin 3'-triphosphate
  • 6-(L-erythro-1,2-Dihydroxypropyl 3-triphosphate)-7,8-dihydropterin
  • 6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin
  • 6-(L-erythro-1,2-dihydroxy-3-triphosphooxypropyl)-7,8-dihydropterin
  • 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridine triphosphate
  • 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)dihydropteridinetriphosphate
  • (2R,3S)-3-(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)-2,3-dihydroxypropyl tetrahydrogen triphosphate

References

  1. ^ Genetics Home Reference. "PTS gene". Genetics Home Reference. Retrieved 3 May 2018.
  2. ^ "dihydroneopterin triphosphate ,CHEBI:18372,7,8-dihydroneopterin 3'-化学物质数据库". www.chemdrug.com. Retrieved 3 May 2018.


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