3,3-Diethyl-2-pyrrolidinone

3,3-Diethyl-2-pyrrolidinone
Clinical data
ATC code
  • none
Identifiers
  • 3,3-Diethylpyrrolidin-2-one
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.162.031 Edit this at Wikidata
Chemical and physical data
FormulaC8H15NO
Molar mass141.214 g·mol−1
3D model (JSmol)
  • CCC1(CC)CCNC1=O
  • InChI=1S/C8H15NO/c1-3-8(4-2)5-6-9-7(8)10/h3-6H2,1-2H3,(H,9,10) checkY
  • Key:WYPUMACPRYGQOM-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

3,3-Diethyl-2-pyrrolidinone (DEABL) is an anticonvulsant drug most closely related to pyrithyldione and gabapentin.[1] It was found to extend lifespan in the nematode worms Caenorhabditis elegans.[2]

References

  1. ^ Hill MW, Reddy PA, Covey DF, Rothman SM (July 1998). "Contribution of subsaturating GABA concentrations to IPSCs in cultured hippocampal neurons". The Journal of Neuroscience. 18 (14): 5103–11. doi:10.1523/JNEUROSCI.18-14-05103.1998. PMC 6793480. PMID 9651194.
  2. ^ Evason K, Huang C, Yamben I, Covey DF, Kornfeld K (January 2005). "Anticonvulsant medications extend worm life-span". Science. 307 (5707): 258–62. Bibcode:2005Sci...307..258E. doi:10.1126/science.1105299. PMID 15653505. S2CID 22154410.


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