Obovatol

Obovatol
Names
Preferred IUPAC name
5-(Prop-2-en-1-yl)-3-[4-(prop-2-en-1-yl)phenoxy]benzene-1,2-diol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C18H18O3/c1-3-5-13-7-9-15(10-8-13)21-17-12-14(6-4-2)11-16(19)18(17)20/h3-4,7-12,19-20H,1-2,5-6H2
    Key: OPGPFZQBCIAFLI-UHFFFAOYSA-N
  • C=CCC1=CC=C(C=C1)OC2=CC(=CC(=C2O)O)CC=C
Properties
C18H18O3
Molar mass 282.339 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Obovatol is a biphenolic anti-inflammatory, anxiolytic, and nootropic isolated from the bark of Magnolia obovata.[1] It is a biphenyl lignan.[2]

References

  1. ^ Choi, DY; Lee, JW; Peng, J; Lee, YJ; Han, JY; Lee, YH; Choi, IS; Han, SB; Jung, JK; Lee, WS; Lee, SH; Kwon, BM; Oh, KW; Hong, JT (2012). "Obovatol improves cognitive functions in animal models for Alzheimer's disease". Journal of Neurochemistry. 120 (6): 1048–59. doi:10.1111/j.1471-4159.2011.07642.x. PMID 22212065. S2CID 25896721.
  2. ^ Obovatol and obovatal, novel biphenyl ether lignans from the leaves of Magnolia obovata Thunb. K Ito, T Iida, K Ichino, M Tsunezuka and M Hattori, … and Pharmaceutical Bulletin, 1982


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