The Buffaloes were 7–2 at one point, losing only to #12 Miami and #2 Texas. The Colorado Buffaloes were champions of the Big 12 North Division, and they faced off against Texas in the Big 12 Championship game. They were soundly defeated in the Big 12 Championship game by eventual BCS Champion Texas 70–3. Texas would go on to win the BCS Championship in the 2006 Rose Bowl. Barnett had survived a recruiting scandal and a suspension following derogatory remarks about a female kicker, Katie Hnida, who claimed she was raped by a teammate in 2000. But the losses to Miami, Iowa State, Nebraska and the second Texas drubbing ultimately led to his forced resignation.[1] Three weeks prior to the game, Colorado head coach Gary Barnett resigned and so the Buffalos were coached by defensive coordinator Mike Hankwitz against Clemson.[1]
Meanwhile, Clemson began their season with a win over #17 Texas A&M at home, with a win over Maryland the following week. However, they lost their next three games (including one over #13 Miami) before a win over NC State righted the ship. They lost only once more to Georgia Tech for the rest of the year, closing out the year with wins over #17 Florida State and #19 South Carolina. They finished in 2nd place in the Atlantic Coast Conference Atlantic Division to Florida State and Boston College, the latter who Clemson had lost to during the skid.
Clemson scored first with a 26 yard field goal by Jad Dean, making it 3–0 Clemson in the opening moments. Colorado's Mason Crosby answered with a 36 yard field goal, tying it at 3. Clemson's Jad Dean kicked another field goal, an 18 yarder, giving Clemson a 6–3 lead. That score held up at half-time.
In the third quarter, quarterback Charlie Whitehurst scored on a 5 yard touchdown run, increasing the lead to 13–3. In the fourth quarter, Brian White threw a 2 yard touchdown pass to Quinn Sypniewski, cutting the margin to 13–10. James Davis added a 6 yard touchdown run to make the final margin 19–10, Clemson.
Colorado made just one more bowl appearance in the decade, in 2007, which they also lost. They have not won a bowl game since 2004. Clemson went to four more bowl games in the decade.