Matches were scheduled to be played at the stadium of the team named first on the date specified for each round, which was always a Saturday. Some matches, however, might be rescheduled for other days if there were clashes with games for other competitions or the weather was inclement. If scores were level after 90 minutes had been played, a replay would take place at the stadium of the second-named team later the same week. If the replayed match was drawn further replays would be held until a winner was determined. If scores were level after 90 minutes had been played in a replay, a 30-minute period of extra time would be played.
The matches were scheduled for Saturday, 9 December 1972, with the exception of the Walsall–Charlton Athletic game which was played three days later. Five matches were drawn, with replays taking place later the same week.
The 44 First and Second Division clubs entered the competition at this stage. The matches were scheduled Saturday, 13 January 1973, with the exception of the Reading–Doncaster Rovers game, which was played on the following Wednesday. Eleven matches were drawn, of which two required a second replay.
The first attempted replay between Nottingham Forest and West Bromwich Albion was abandoned in the 81st minute with the score at 1–1 due to fog at the City Ground. It was successfully re-staged six days later but was drawn 0–0, necessitating a second replay.
The semi-final matches were played on Saturday, 7 April 1973 with no replays being needed. Sunderland and Leeds United won their respective matches to go on to the final at Wembley.
The final took place on Saturday, 5 May 1973 at Wembley and ended in a victory for Sunderland over Leeds United by one goal to nil. The attendance was 100,000.