Barry Trost

Barry M. Trost (Juni 2012)

Barry M. Trost (* 13. Juni 1941 in Philadelphia) ist ein US-amerikanischer Chemiker und Professor für Chemie an der Stanford University.

Leben und Werk

Er studierte an der University of Pennsylvania. Für seine Dissertation über Die Struktur und Reaktivität von Enolat-Anionen wechselte er an das Massachusetts Institute of Technology in die Arbeitsgruppe von Herbert O. House. Er war von 1965 bis 1987 Professor an der University of Wisconsin und wechselte dann an die Stanford University.

Die Tsuji-Trost-Reaktion und der Trost-Ligand sind nach ihm benannt. Er gehört nach eigenen Angaben zu den 50 am häufigsten zitierten Chemikern der Welt.

Der Forschungsschwerpunkt liegt auf der Synthese, wobei die Entwicklung neuer Reaktionen und Reagenzien sowie die Entwicklung eines Netzwerks von Reaktionen (siehe auch Tandem-Reaktion), um aus einfachen Molekülen komplexe Zielmoleküle aufzubauen. Für die Entwicklung neuer Reaktionen wird die Route der sogenannten Chemie-Enzyme verfolgt, das sind nicht-peptidische übergangsmetallbasierte Katalysatoren mit chemo-, regio- und enantioselektiven Eigenschaften. Zielmoleküle sind unter anderem durch Metallkatalyse hergestellte Ringverbindungen mit mehr als sechs Ringgliedern.

Ehrungen, Preise und Mitgliedschaften (Auswahl)

Veröffentlichungen (Auswahl)

Fachbücher

  • M. L. Crawley, B. M. Trost: Applications of Transition Metal Catalysis in Drug Discovery and Development. John Wiley & Sons, 2012, ISBN 1-118-30983-9 eingeschränkte Vorschau in der Google-Buchsuche
  • B. M. Trost: Stereocontrolled Organic Synthesis. Blackwell Scientific Publications, 1994, ISBN 0-86542-833-6
  • B. M. Trost, M. F. Semmelhack, I. Fleming: Comprehensive Organic Synthesis: Additions to and Substitutions at C-C Pi-Bonds. Verlag Elsevier, 1991, ISBN 0-08-040595-9 eingeschränkte Vorschau in der Google-Buchsuche
  • B. M. Trost: Problems in Spectroscopy, W.A. Benjamin Co., 1977
  • B. M. Trost, L. S. Melvin: Sulfur Ylides – Emerging Synthetic Intermediates, Academic Press, 1975, ISBN 0-12-701060-2

Fachartikel

Commons: Barry Trost – Sammlung von Bildern, Videos und Audiodateien
Personendaten
NAME Trost, Barry
ALTERNATIVNAMEN Trost, Barry M.
KURZBESCHREIBUNG US-amerikanischer Chemiker
GEBURTSDATUM 13. Juni 1941
GEBURTSORT Philadelphia

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