Den 13th Annual Screen Actors Guild Awards uddeling, for at ære de bedste film- og TV-skuespillere for året 2006, foregik den 28. januar 2007. Hvem der var nomineret til hvad, blev afsløret den 4. januar 2007.^[1]

Babel, Dreamgirls og Little Miss Sunshine, var dem der fik det højeste af nominationer i filmkategorierne, ved at få 3 nominationer hver; to for skuespillet og en for bedste cast. Trods de mange nomineringer var det dog kun Dreamgirls der vandt mere end én award. I fjernsynskategorierne var det The Sopranos og Broken Trail, som begge hver fik 3 nomineringer, men det var mini-serien Elizabeth I og drama-serien Grey's Anatomy, der vandt flest awards med to hver.

Screen Actors Guild Life Achievement Award gik til skuespilleren Julie Andrews.^[2]

Forest Whitaker – The Last King of Scotland

• Leonardo DiCaprio – Blood Diamond
• Ryan Gosling – Half Nelson
• Peter O'Toole – Venus
• Will Smith – The Pursuit of Happyness

Helen Mirren – The Queen

• Penelope Cruz – Volver
• Judi Dench – Notes on a Scandal
• Meryl Streep – The Devil Wears Prada
• Kate Winslet – Little Children

Eddie Murphy – Dreamgirls

• Alan Arkin – Little Miss Sunshine
• Leonardo DiCaprio – The Departed
• Jackie Earle Haley – Little Children
• Djimon Hounsou – Blood Diamond

Jennifer Hudson – Dreamgirls

• Adriana Barraza – Babel
• Cate Blanchett – Notes on a Scandal
• Abigail Breslin – Little Miss Sunshine
• Rinko Kikuchi – Babel

Little Miss Sunshine

Alan Arkin

Abigail Breslin

Steve Carell

Toni Collette

Paul Dano

Greg Kinnear

• Babel
• Bobby
• The Departed
• Dreamgirls

Jeremy Irons – Elizabeth I

• Thomas Haden Church – Broken Trail
• Robert Duvall – Broken Trail
• William H. Macy – Nightmares and Dreamscapes
• Matthew Perry – The Ron Clark Story

Helen Mirren – Elizabeth I

• Annette Bening – Mrs. Harris
• Shirley Jones – Hidden Places
• Cloris Leachman – Mrs. Harris
• Greta Scacchi – Broken Trail

Hugh Laurie – House

• James Gandolfini – The Sopranos
• Michael C. Hall – Dexter
• James Spader – Boston Legal
• Kiefer Sutherland – 24 timer

Chandra Wilson – Grey's Anatomy

• Patricia Arquette – Medium
• Edie Falco – The Sopranos
• Mariska Hargitay – Law & Order: Special Victims Unit
• Kyra Sedgwick – The Closer

Alec Baldwin – 30 Rock

• Steve Carell – The Office
• Jason Lee – My Name Is Earl
• Jeremy Piven – Entourage
• Tony Shalhoub – Monk

America Ferrera – Ugly Betty

• Felicity Huffman – Desperate Housewives
• Julia Louis-Dreyfus – The New Adventures of Old Christine
• Megan Mullally – Will & Grace
• Mary-Louise Parker – Weeds
• [aime Pressly – My Name Is Earl

Grey's Anatomy

Justin Chambers

Eric Dane

Patrick Dempsey

Katherine Heigl

TR Knight

Sandra Oh

James Pickens, Jr.

Ellen Pompeo

Sara Ramirez

Kate Walsh

Isaiah Washington

Chandra Wilson

• 24 timer
• Boston Legal
• Deadwood
• The Sopranos

The Office

Leslie David Baker

Brian Baumgartner

Steve Carell

David Denman

Jenna Fischer

Kate Flannery

Melora Hardin

Mindy Kaling

Angela Kinsey

John Krasinski

Paul Lieberstein

B.J. Novak

Oscar Nunez

Phyllis Smith

Rainn Wilson

• Desperate Housewives
• Entourage
• Ugly Betty
• Weeds

Julie Andrews