Her career started at the youth teams of amateur club Reiger Boys in Heerhugowaard.[5] She then played for Kolping Boys youth team, another amateur club in Oudorp.[6]
A move to AZ Alkmaar in 2009 started her professional career, as she was able to play in the highest professional national league (Eredivisie). After two seasons at the club, in 2011, she joined Telstar where she played for the next four years. In 2015 she moved to FC Twente[7] and after one season she joined the German Bundesliga team Bayern Munich.[8] Due to injuries, she had few opportunities to play in Germany and in 2017 she moved back to the Netherlands, signing with Ajax.[9]
On 4 July 2018, she joined Spanish side FC Barcelona.[10]
On 12 June 2020, she moved back to join AFC Ajax.[11] On 5 August 2022, Van der Gragt joined Italian club Inter Milan.[12]
In April 2023 she announced her retirement after the 2023 World Cup to join back AZ Alkmaar as manager.[13]
On 31 May 2023, she was named as part of the Netherlands provisional squad for the 2023 FIFA Women's World Cup.[18]
She scored in the Netherlands' opening match of the tournament against Portugal which was the only goal of the match. It meant Van der Gragt scored in successive World Cups.[19]
International goals
Scores and results list the Netherlands goal tally first.[14]