PROFILPELAJAR.COM

Sinus tachycardia
Sinus tachycardia
	ECG of a 29-year-old female with sinus tachycardia with a heart rate of 125 bpm
Specialty	Cardiology

Sinus tachycardia is a sinus rhythm of the heart, with an increased rate of electrical discharge from the sinoatrial node, resulting in a tachycardia, a heart rate that is higher than the upper limit of normal (90-100 beats per minute for adult humans).^[1]

The normal resting heart rate is 60–90 bpm in an average adult.^[2] Normal heart rates vary with age and level of fitness, from infants having faster heart rates (110-150 bpm) and the elderly having slower heart rates.^[3] Sinus tachycardia is a normal response to physical exercise or other stress, when the heart rate increases to meet the body's higher demand for energy and oxygen, but sinus tachycardia can also be caused by a health problem.^[4]

An elite athlete's heart recorded during a maximum effort workout maintaining over 180 bpm for 10 minutes.

Signs and symptoms

Tachycardia is often asymptomatic. It is often a resulting symptom of a primary disease state and can be an indication of the severity of a disease.^[5] If the heart rate is too high, cardiac output may fall due to the markedly reduced ventricular filling time.^[6] Rapid rates, though they may be compensating for ischemia elsewhere, increase myocardial oxygen demand and reduce coronary blood flow, thus precipitating an ischemic heart or valvular disease.^[5] Sinus tachycardia accompanying a myocardial infarction may be indicative of cardiogenic shock.^{[citation needed]}

Cause

Sinus tachycardia is usually a response to physiological stress, such as exercise, or an increased sympathetic tone with increased catecholamine release, such as stress, fright, flight, and anger.^[5] Other causes include:

Pain^[7]
Fever^[7]
Anxiety^[7]
Dehydration^[7]
Excess cortisol^[8]
Malignant hyperthermia
Hypovolemia with hypotension and shock
Anemia^[7]
Hyperthyroidism^[7]
Mercury poisoning
Kawasaki disease
Pheochromocytoma
Sepsis^[7]
Pulmonary embolism^[7]
Acute coronary ischemia and myocardial infarction
Chronic obstructive pulmonary disease
Hypoxia
Intake of stimulants such as caffeine, theophylline, nicotine, cocaine, or amphetamines^[7]
Hyperdynamic circulation
Electric shock
Drug withdrawal^[7]
Porphyria
Acute inflammatory demyelinating polyradiculoneuropathy
Postural orthostatic tachycardia syndrome
Mitral valve prolapse
Metabolic myopathies^[4]^[9]^[10]^[11]^[12]

Diagnosis

Sinus tachycardia is usually apparent on an ECG, but if the heart rate is above 140 bpm the P wave may be difficult to distinguish from the previous T wave and one may confuse it with a paroxysmal supraventricular tachycardia or atrial flutter with a 2:1 block. Ways to distinguish the three are:^{[citation needed]}

Vagal maneuvers (such as carotid sinus massage or Valsalva's maneuver) to slow the rate and identification of P waves
administer AV blockers (e.g., adenosine, verapamil) to identify atrial flutter with 2:1 block

Heart sounds should also be listened to.^[13]

ECG characteristics

Rate: Greater than or equal to 100.^[13]
Rhythm: Regular.^[13]
P waves: Upright, in leads I, II and aVL, and negative in lead aVR;^[13]
each P wave is followed by a QRS and T waves^[13]

Inappropriate sinus tachycardia

In inappropriate sinus tachycardia (also known as chronic nonparoxysmal sinus tachycardia), patients have an elevated resting heart rate and/or exaggerated heart rate in response to exercise. These patients have no apparent heart disease or other causes of sinus tachycardia. IST is thought to be due to abnormal autonomic control.^{[citation needed]} IST is a diagnosis of exclusion.^[14]

Postural orthostatic tachycardia syndrome

Usually, in women with no heart problems, this syndrome is characterized by normal resting heart rate but exaggerated postural sinus tachycardia with or without orthostatic hypotension.^{[citation needed]}

Metabolic myopathy

Upon exertion, sinus tachycardia can be seen in some inborn errors of metabolism that result in metabolic myopathies, such as McArdle Disease (GSD-V)^[9]^[12] and Hereditary myopathy with lactic acidosis (Larsson–Linderholm syndrome).^[4]^[15] Metabolic myopathies interfere with the muscle's ability to create energy. This energy shortage in muscle cells causes an inappropriate rapid heart rate response to exercise. The heart tries to compensate for the energy shortage by increasing heart rate to maximize delivery of oxygen and other blood borne fuels to the muscle cells.^[9]^[4]

In one such category of metabolic myopathies, muscle glycogenoses (muscle GSDs), individuals are unable to create energy from muscle glycogen, and depending on the muscle GSD, may not be able to utilize blood glucose within the muscle cell either.^[9] As skeletal muscle relies predominantly on glycogenolysis for the first few minutes as it transitions from rest to activity, as well as throughout high-intensity aerobic activity and all anaerobic activity, individuals with glycogenoses experience during exercise: sinus tachycardia, tachypnea, muscle fatigue and pain, during the aforementioned activities and time frames.^[9]^[10] Notable in McArdle Disease (GSD-V) is the phenomenon of second wind where after approximately 6–10 minutes of aerobic exercise, such as walking without an incline, the heart rate drops as blood borne fuels, predominantly from free fatty acids, produce energy via oxidative phosphorylation.^[9]^[10]^[16]

Rare diseases, such as McArdle disease, are often misdiagnosed.^[9] The inappropriate rapid heart rate response to exercise may be misdiagnosed as inappropriate sinus tachycardia (which is a diagnosis of exclusion).

Treatment

Treatment for physiologic sinus tachycardia involves treating the underlying causes of the tachycardia response. Beta blockers may be used to decrease tachycardia in patients with certain conditions, such as ischemic heart disease and rate-related angina. In patients with inappropriate sinus tachycardia, careful titration of beta-blockers, salt loading, and hydration typically reduce symptoms. Patients who are unresponsive to such treatment can undergo catheter ablation to potentially repair the sinus node.^[3]

Acute myocardial infarction (AMI)

Sinus tachycardia can present in more than a third of the patients with AMI but this usually decreases over time. Patients with sustained sinus tachycardia reflects a larger infarct that are more anterior with prominent left ventricular dysfunction, associated with high mortality and morbidity. Tachycardia in the presence of AMI can reduce coronary blood flow and increase myocardial oxygen demand, aggravating the situation. Beta-blockers can be used to slow the rate, but most patients are usually already treated with beta-blockers as a routine regimen for AMI.^{[citation needed]}

IST and POTS

Beta blockers are useful if the cause is sympathetic overactivity. If the cause is due to decreased vagal activity, it is usually hard to treat and one may consider radiofrequency catheter ablation.^{[citation needed]}

Notes

References

^ Crawford, Michael H., ed. (2017). Current diagnosis & treatment cardiology (5th ed.). New York: McGraw-Hill Education. ISBN 9781259641268. OCLC 973336660.
^ MD, Howard E. LeWine (2011-12-21). "Increase in resting heart rate is a signal worth watching". Harvard Health. Retrieved 2022-04-05.
^ ^a ^b Jameson, J. N. St C.; Dennis L. Kasper; Harrison, Tinsley Randolph; Braunwald, Eugene; Fauci, Anthony S.; Hauser, Stephen L; Longo, Dan L. (2005). Harrison's principles of internal medicine. New York: McGraw-Hill Medical Publishing Division. pp. 1344–58. ISBN 978-0-07-140235-4.
^ ^a ^b ^c ^d Saltin, Bengt (2000). Exercise and Circulation in Health and Disease. (Ch. 21 Circulatory Regulation in Muscle Disease). Human Kinetics. ISBN 978-0-88011-632-9.
^ ^a ^b ^c Lilly, Leonard S. Pathophysiology of heart disease: a collaborative project of medical students and faculty (6th ed.). Philadelphia: Wolters Kluwer. ISBN 9781469897585. OCLC 925544683.
^ Emergency Care And Transportation Of The Sick And Injured. Jones & Bartlett Learning. 2010. ISBN 978-1-4496-1589-5.
^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j Olshansky, Brian; Sullivan, Renee M (2018-06-19). "Inappropriate sinus tachycardia". EP Europace. 21 (2): 194–207. doi:10.1093/europace/euy128. PMID 29931244.
^ Zhao YX, Ma WL, Lu L (2022). "Appendiceal Neuroendocrine Tumor Is a Rare Cause of Ectopic Adrenocorticotropic Hormone Syndrome With Cyclic Hypercortisolism: A Case Report and Literature Review". Frontiers in Endocrinology. 13: 808199. doi:10.3389/fendo.2022.808199. PMC 8896118. PMID 35250866.
^ ^a ^b ^c ^d ^e ^f ^g Lucia A; Martinuzzi A; Nogales-Gadea G; Quinlivan R; Reason S; et al. (International Association for Muscle Glycogen Storage Disease study group) (28 October 2021). "Clinical practice guidelines for glycogen storage disease V & VII (McArdle disease and Tarui disease) from an international study group". Neuromuscul Disord. 31 (12) (published December 2021): 1296–1310. doi:10.1016/j.nmd.2021.10.006. PMID 34848128. (Erratum: doi:10.1016/j.nmd.2022.01.004, PMID 35140027)
^ ^a ^b ^c Scalco RS; Chatfield S; Godfrey R; Pattni J; Ellerton C; Beggs A; Brady S; Wakelin A; Holton JL; Quinlivan R (July 2014). "From exercise intolerance to functional improvement: the second wind phenomenon in the identification of McArdle disease". Arq Neuropsiquiatr. 72 (7): 538–541. doi:10.1590/0004-282x20140062. PMID 25054987.
^ Wakelin, Andrew (2017). Living With McArdle Disease (PDF). IAMGSD (International Association for Glycogen Storage Disease). p. 15.
^ ^a ^b Noury, Jean-Baptiste; Zagnoli, Fabien; Petit, François; Marcorelles, Pascale; Rannou, Fabrice (2020-05-29). "Exercise efficiency impairment in metabolic myopathies". Scientific Reports. 10 (1): 8765. Bibcode:2020NatSR..10.8765N. doi:10.1038/s41598-020-65770-y. ISSN 2045-2322. PMC 7260200. PMID 32472082.
^ ^a ^b ^c ^d ^e Allison Henning; Conrad Krawiec (2020). "Sinus Tachycardia". StatPearls. PMID 31985921.
^ Ahmed A; Pothineni N; Charate R; et al. (June 2022). "Inappropriate Sinus Tachycardia: Etiology, Pathophysiology, and Management". J Am Coll Cardiol. 79 (24): 2450–2462. doi:10.1016/j.jacc.2022.04.019. PMID 35710196.
^ Larsson, L. E.; Linderholm, H.; Mueller, R.; Ringqvist, T.; Soernaes, R. (October 1964). "Hereditary metabolic myopathy with paroxysmal myoglobinuria due to abnormal glycolysis". Journal of Neurology, Neurosurgery, and Psychiatry. 27 (5): 361–380. doi:10.1136/jnnp.27.5.361. ISSN 0022-3050. PMC 495765. PMID 14213465.
^ Salazar-Martínez E; Santalla A; Valenzuela PL; Nogales-Gadea G; Pinós T; Morán M; Santos-Lozano A; Fiuza-Luces C; Lucia A (15 October 2021). "The Second Wind in McArdle Patients: Fitness Matters". Front Physiol. 12 744632: 744632. doi:10.3389/fphys.2021.744632. PMC 8555491. PMID 34721068.

Hall, John E.; Guyton, Arthur C. (2000). Textbook of medical physiology. Philadelphia: W. B. Saunders. ISBN 978-0-7216-8677-6.
Choudhury SR, Sharma A, Kohli V (February 2005). "Inappropriate sinus node tachycardia following gastric transposition surgery in children". Pediatric Surgery International. 21 (2): 127–8. doi:10.1007/s00383-004-1354-9. PMID 15654608. S2CID 39302980.
Sinus tachycardia

External links

[1] Crawford, Michael H., ed. (2017). Current diagnosis & treatment cardiology (5th ed.). New York: McGraw-Hill Education. ISBN 9781259641268. OCLC 973336660.

[2] MD, Howard E. LeWine (2011-12-21). "Increase in resting heart rate is a signal worth watching". Harvard Health. Retrieved 2022-04-05.

[principals-3] Jameson, J. N. St C.; Dennis L. Kasper; Harrison, Tinsley Randolph; Braunwald, Eugene; Fauci, Anthony S.; Hauser, Stephen L; Longo, Dan L. (2005). Harrison's principles of internal medicine. New York: McGraw-Hill Medical Publishing Division. pp. 1344–58. ISBN 978-0-07-140235-4.

[:5-4] Saltin, Bengt (2000). Exercise and Circulation in Health and Disease. (Ch. 21 Circulatory Regulation in Muscle Disease). Human Kinetics. ISBN 978-0-88011-632-9.

[:0-5] Lilly, Leonard S. Pathophysiology of heart disease: a collaborative project of medical students and faculty (6th ed.). Philadelphia: Wolters Kluwer. ISBN 9781469897585. OCLC 925544683.

[aaos-6] Emergency Care And Transportation Of The Sick And Injured. Jones & Bartlett Learning. 2010. ISBN 978-1-4496-1589-5.

[Olshansky_Sullivan_pp._194–207-7] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j Olshansky, Brian; Sullivan, Renee M (2018-06-19). "Inappropriate sinus tachycardia". EP Europace. 21 (2): 194–207. doi:10.1093/europace/euy128. PMID 29931244.

[pmid35250866-8] Zhao YX, Ma WL, Lu L (2022). "Appendiceal Neuroendocrine Tumor Is a Rare Cause of Ectopic Adrenocorticotropic Hormone Syndrome With Cyclic Hypercortisolism: A Case Report and Literature Review". Frontiers in Endocrinology. 13: 808199. doi:10.3389/fendo.2022.808199. PMC 8896118. PMID 35250866.

[:1-9] ^ ^a ^b ^c ^d ^e ^f ^g Lucia A; Martinuzzi A; Nogales-Gadea G; Quinlivan R; Reason S; et al. (International Association for Muscle Glycogen Storage Disease study group) (28 October 2021). "Clinical practice guidelines for glycogen storage disease V & VII (McArdle disease and Tarui disease) from an international study group". Neuromuscul Disord. 31 (12) (published December 2021): 1296–1310. doi:10.1016/j.nmd.2021.10.006. PMID 34848128. (Erratum: doi:10.1016/j.nmd.2022.01.004, PMID 35140027)

[:2-10] Scalco RS; Chatfield S; Godfrey R; Pattni J; Ellerton C; Beggs A; Brady S; Wakelin A; Holton JL; Quinlivan R (July 2014). "From exercise intolerance to functional improvement: the second wind phenomenon in the identification of McArdle disease". Arq Neuropsiquiatr. 72 (7): 538–541. doi:10.1590/0004-282x20140062. PMID 25054987.

[:3-11] Wakelin, Andrew (2017). Living With McArdle Disease (PDF). IAMGSD (International Association for Glycogen Storage Disease). p. 15.

[:4-12] Noury, Jean-Baptiste; Zagnoli, Fabien; Petit, François; Marcorelles, Pascale; Rannou, Fabrice (2020-05-29). "Exercise efficiency impairment in metabolic myopathies". Scientific Reports. 10 (1): 8765. Bibcode:2020NatSR..10.8765N. doi:10.1038/s41598-020-65770-y. ISSN 2045-2322. PMC 7260200. PMID 32472082.

[stats-13] Allison Henning; Conrad Krawiec (2020). "Sinus Tachycardia". StatPearls. PMID 31985921.

[14] Ahmed A; Pothineni N; Charate R; et al. (June 2022). "Inappropriate Sinus Tachycardia: Etiology, Pathophysiology, and Management". J Am Coll Cardiol. 79 (24): 2450–2462. doi:10.1016/j.jacc.2022.04.019. PMID 35710196.

[15] Larsson, L. E.; Linderholm, H.; Mueller, R.; Ringqvist, T.; Soernaes, R. (October 1964). "Hereditary metabolic myopathy with paroxysmal myoglobinuria due to abnormal glycolysis". Journal of Neurology, Neurosurgery, and Psychiatry. 27 (5): 361–380. doi:10.1136/jnnp.27.5.361. ISSN 0022-3050. PMC 495765. PMID 14213465.

[16] Salazar-Martínez E; Santalla A; Valenzuela PL; Nogales-Gadea G; Pinós T; Morán M; Santos-Lozano A; Fiuza-Luces C; Lucia A (15 October 2021). "The Second Wind in McArdle Patients: Fitness Matters". Front Physiol. 12 744632: 744632. doi:10.3389/fphys.2021.744632. PMC 8555491. PMID 34721068.

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

[11]

[12]

[13]

[14]

[15]

[16]

PROFILPELAJAR.COM

Sinus tachycardia

Signs and symptoms

Cause

Diagnosis

ECG characteristics

Inappropriate sinus tachycardia

Postural orthostatic tachycardia syndrome

Metabolic myopathy

Treatment

Acute myocardial infarction (AMI)

IST and POTS

Notes

See also

References

External links

Read other articles:

The Root (magazine)

Christian Vieri

Caño Cristales

Kerajaan Armenia Kilikia

Stranger Things (Kygo song)

1912 United States presidential election in Virginia

Swish (payment)

Vidar Nisja

Sweden in the Eurovision Song Contest 1961

Friedrich Hartogs

Chandra Wilson

土库曼斯坦总统

哈萨克斯坦总统

Diego Mariño

Nevada Division of Child and Family Services

Superficial vein

1st Armoured Infantry Brigade (United Kingdom)

橋本 (福岡市)

Axiom of choice

Code folding