Naagulu, a snake charmer, falls in love with Poorna, whose adopted brother Ravi is in love with Naagulu's cousin Lakshmi. Naagulu's father has been mixing snake venom into his food since childhood, making Naagulu immune to any snake bite. Every full moon, Naagulu behaves like a cobra and searches for a woman and every woman he meets dies from his poison. On one such full moon, he kills Poorna and Ravi gets suspicious about this, as there are no marks of a snake bite on her body. A young teacher comes to the village and becomes Naagulu's victim. Ravi investigates with the help of film in her still camera and discovers that Naagulu appears as a snake in a photo she took of him. Naagulu's father reveals his secret before dying and Naagulu tries to find a remedy, but it's too late for that. His skin starts peeling off like a snake and Ravi advises him to leave the village before villagers find and kill him. Naagulu prefers death to the life of a snake and commits suicide from a hilltop.