The founder was Marin de Prodanello (fl. 1273-1304), also called Bauxellus; his descendants, apart from "Prodanello", used Bausella as a surname.[2] Another branch of the family, led by Ursacius Prodanelli (fl. 1253–85)[3] (most likely Marin's brother[2]), did not use the Bausella name.[2] Ursacius' sons were distinguished Ragusan officials: Petrus (fl. 1280–1311)[3] was senator and judge,[2] while Johannes (fl. 1283–97)[3] was canon and notary.[2] They were among the eleven smallest houses in the 15th century.[4]
Another Petar Prodančić, son of Marin, was merchant who did business in medieval Serbian state. His brother Vito (Vitus/Vid) had two sons, Marin and Petar, who continued family business in Serbia. Petar had five sons, among which Jacob (Jakov/Jakša), James (Giacomo) and Theodore (Teodoro/Teodor) were most successful by the end of the 14th century and the beginning of the 15th century. Jacob was merchant and diplomat, and was succeeded by his son Nicholas (Nicola/Nikola/Nikša) while Teodor was succeeded by his son Petar.
In the 16th century there were two last Prodančić family branches left. One of them was that of Petar (~ 1504-1563), son of Nikola, and the other one was that of Stephen (Stefano/Stjepan/Stijepo; 1566-1638), who was the last male member of the family.
In the two-century-long period of time, from 1440 to 1640, there were in total 24 members of the family who entered the Grand Council (Consilium maius), a body consisting of all adult Ragusan noblemen. Twenty of them were elected to the Senate and twenty as Rector (knez) of the Republic, the head of the state.