The film was written by Mike MacLean, who had written Dinocroc vs. Supergator and a number of scripts for Roger Corman. Corman hired him to write the film.[3]
MacLean said: "I learned from Roger that a cable movie is a different animal than a theatrical release. First and foremost, cable movies must be faster-paced. With a theatrical release, the audience has driven to the mall, bought a ticket, and fought the crowds for a seat. They've made an investment in the viewing experience, so they're not walking out on the film if it's pacing is a bit leisurely. A cable movie audience has the remote within reach... So you have to keep things moving, which means showing the creature soon and often".[3]
MacLean added that "these films must have an element of comedic irony... the effects still can't compete with the big studio blockbusters. So there has to be a comedic undercurrent to the story. Audiences are more likely to accept a less-than-realistic effect if they know they're laughing with the filmmakers".[3]
In Nessie & Me, the character Jack O'Grady mentions the Dinocroc/Supergator and the Piranhaconda when he encounters Nessie at the beginning of the movie. However, those three films are not related to the first one.