It was founded in 1786 and named after its founder, the army officer Ivan Abramovich Müller, who set up a farm estate after he received vacant land by the river deep in the Decree of the EmpressCatherine the Great on February 14, 1786.[8] At the end of the 19th century, it became an important railway hub. Facilities were built to process a large part of agricultural products coming from the areas of the upper Don and Ukraine to send to the central provinces of Russia. It was granted town status in 1926.[9]
During World War II, in July 1942, an encirclement of Soviet troops by Wehrmacht forces occurred around the town as part of the German Case Blue, resulting in around 50,000 Soviet soldiers being captured.[10] Conversely, in December 1942 the Soviets encircled retreating German and Italian units under the command of General Hans Kreysing in the city. Millerovo was liberated on January 16, 1942, after the remaining Axis troops broke through the encirclement towards the west.
The Millerovo military airfield is located 5 kilometers (3.1 mi) northwest of the town. At the airfield was stationed the headquarters of the 16th Guards Fighter Aviation Division after its withdrawal from Germany in 1993 until 1998. Also until 2009, the 19th Nikopol Guards Fighter Aviation Regiment (19 Gv IAP)—a part of the 51st Air Defense Corps of the 4th Army of Air Force and Air Defense—was stationed there. The regiment was reorganized in 2009 as the 6969th Air Base, a part of the 7th Brigade of Military-Space Defense. MiG-29 fighters of both the former 19th GvIAP and the 31st Fighter Air Regiment, previously disbanded in Zernograd, are located at the airfield.
Законодательное Собрание Ростовской области. Закон №340-ЗС от 25 июля 2005 г. «Об административно-территориальном устройстве Ростовской области», в ред. Закона №270-ЗС от 27 ноября 2014 г. «О внесении изменений в областной Закон "Об административно-территориальном устройстве Ростовской области"». Вступил в силу со дня официального опубликования. Опубликован: "Наше время", №187–190, 28 июля 2005 г. (Legislative Assembly of Rostov Oblast. Law #340-ZS of July 28, 2005 On the Administrative-Territorial Structure of Rostov Oblast, as amended by the Law #270-ZS of November 27, 2014 On Amending the Oblast Law "On the Administrative-Territorial Structure of Rostov Oblast". Effective as of the official publication date.).
Законодательное Собрание Ростовской области. Закон №171-ЗС от 22 октября 2004 г. «Об установлении границ и наделении соответствующим статусом муниципального образования "Миллеровский район" и муниципальных образований в его составе», в ред. Закона №981-ЗС от 25 октября 2012 г. «О внесении изменений в областной Закон "Об установлении границ и наделении соответствующим статусом муниципального образования "Миллеровский район" и муниципальных образований в его составе"». Вступил в силу с 1 января 2005 г. Опубликован: "Наше время", №№259–260, 28 октября 2004 г. (Legislative Assembly of Rostov Oblast. Law #171-ZS of October 22, 2004 On Establishing the Borders and Granting an Appropriate Status to the Municipal Formation of "Millerovsky District" and to the Municipal Formations It Comprises, as amended by the Law #981-ZS of October 25, 2012 On Amending the Oblast Law "On Establishing the Borders and Granting an Appropriate Status to the Municipal Formation of "Millerovsky District" and to the Municipal Formations It Comprises". Effective as of January 1, 2005.).