Amewou was born in Lomé, Togo. In January 2008 he moved from Togo-based club OC Agaza to Norwegian club Strømsgodset IF.[2] Before moving back to Togo he was one of the best midfielders in Ghana, he played for Heart of Lions in Kpandu.
On 11 June 2010, the French Ligue 2 club Nîmes Olympique signed the Togolese midfielder on a three-year contract, he joined for an undisclosed fee from Strømsgodset IF.[3]