Samuel was elected as a Republican to the Fifty-ninth Congress. He was an unsuccessful candidate for reelection in 1906 and for election in 1908. He resumed the practice of medicine in Mount Carmel and served as president and general manager of the Shamokin-Mount Carmel Transit Co. from 1908 to 1924. He retired in 1925 and moved to Brooklyn, New York. He died in Mount Carmel in 1930. He was buried in the Mount Carmel Cemetery.