Huff was elected as a Republican to the Fifty-second Congress. He was again elected to the Fifty-fourth Congress. He was not a candidate for renomination in 1896.
On March 16, 1871, Huff married the former Henrietta Burrell, a daughter of Jeremiah M. Burrell, President Judge of the Tenth Judicial District of Pennsylvania. They were the parents of eight children.
^"Hon. George Franklin Huff". Westmoreland County Genealogy Project. April 12, 1999. Retrieved January 26, 2014. moved to Norristown, and from there to Middletown, in Dauphin County, and five years later removed to Altoona, Pennsylvania. ... When four years of age he accompanied his parents to Middletown, where he attended the public schools until 1851, when his parents moved to Altoona.
^"Building". Embassy of Argentina. Archived from the original on 2019-07-28. Retrieved 2017-06-13.