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Calycosin
Names
	IUPAC name 3′,7-Dihydroxy-4′-methoxyisoflavone
	Systematic IUPAC name 7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one
	Other names 7,3′-Dihydroxy-4′-methoxyisoflavone; 3′-Hydroxyformononetin
Identifiers
CAS Number	20575-57-9 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:17793 ;
ChEMBL	ChEMBL241608 ;
ChemSpider	4444104 ;
ECHA InfoCard	100.222.904
PubChem CID	5280448;
UNII	09N3E8P7TA ;
CompTox Dashboard (EPA)	DTXSID70174580 ;
	InChI InChI=1S/C16H12O5/c1-20-14-5-2-9(6-13(14)18)12-8-21-15-7-10(17)3-4-11(15)16(12)19/h2-8,17-18H,1H3 Key: ZZAJQOPSWWVMBI-UHFFFAOYSA-N ;
	SMILES O=C\1c3c(O/C=C/1c2ccc(OC)c(O)c2)cc(O)cc3;
Properties
Chemical formula	C16H12O5
Molar mass	284.267 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Calycosin is an O-methylated isoflavone. It can be isolated from Astragalus membranaceus Bge. var. mongholicus^[1] and Trifolium pratense L. (red clover).^[2]

Biosynthesis

Isoflavone 3′-hydroxylase uses formononetin, NADPH, H⁺ and O₂ to produce calycosin, NADP⁺ and H₂O.

^ Ma, Xiaofeng; Zhang, Tianyou; Wei, Yun; Tu, Pengfei; Chen, Yingjie; Ito, Yoichiro (2002). "Preparative isolation and purification of calycosin from Astragalus membranaceus Bge. var. mongholicus (Bge.) Hsiao by high-speed counter-current chromatography". Journal of Chromatography A. 962 (1–2): 243–7. doi:10.1016/S0021-9673(02)00535-6. PMID 12198969.
^ Biggs, David R; Lane, Geoffrey A (1978). "Identification of isoflavones calycosin and pseudobaptigenin in Trifolium pratense". Phytochemistry. 17 (9): 1683. Bibcode:1978PChem..17.1683B. doi:10.1016/S0031-9422(00)94679-X.