The 1944 United States Senate election in Arkansas took place on November 7, 1944. Incumbent Senator Hattie Caraway ran for a third term in office, but was eliminated in the Democratic primary. U.S. Representative J. William Fulbright defeated Governor Homer Martin Adkins in the Democratic runoff.
Fulbright easily defeated Republican Victor Wade in the general election, in a landslide victory typical for Arkansas Democrats at the time.