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The year 1643 in science and technology involved some significant events.

Exploration

January 21 – Abel Tasman discovers the Tonga archipelago.
December 25 – Captain William Mynors of the British East India Company discovers Christmas Island.^[1]

April 9 – Benedetto Castelli, Italian mathematician (born 1578)
November 3
- John Bainbridge, English astronomer (born 1582)
- Paul Guldin, Swiss mathematician and astronomer (born 1577)
Sophia Brahe, Danish astronomer (born 1556)
Gasparo Berti, Italian mathematician, astronomer and physicist (born c. 1600)
Walter Warner, English scientist (born 1563)

^ "Christmas Island history". Australian Government, Department of Sustainability, Environment, Water, Population and Communities. 2011-11-02. Archived from the original on 2012-03-04. Retrieved 2011-12-09.
^ Torricelli, Evangelista (1715). "Introduction". Lezioni Accademiche. Florence.
^ BnF 12462161b