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1443 in various calendars
Gregorian calendar	1443; MCDXLIII
Ab urbe condita	2196
Armenian calendar	892; ԹՎ ՊՂԲ
Assyrian calendar	6193
Balinese saka calendar	1364–1365
Bengali calendar	849–850
Berber calendar	2393
English Regnal year	21 Hen. 6 – 22 Hen. 6
Buddhist calendar	1987
Burmese calendar	805
Byzantine calendar	6951–6952
Chinese calendar	壬戌年 (Water Dog); 4140 or 3933; — to —; 癸亥年 (Water Pig); 4141 or 3934
Coptic calendar	1159–1160
Discordian calendar	2609
Ethiopian calendar	1435–1436
Hebrew calendar	5203–5204
Hindu calendars
- Vikram Samvat	1499–1500
- Shaka Samvat	1364–1365
- Kali Yuga	4543–4544
Holocene calendar	11443
Igbo calendar	443–444
Iranian calendar	821–822
Islamic calendar	846–847
Japanese calendar	Kakitsu 3; (嘉吉３年)
Javanese calendar	1358–1359
Julian calendar	1443; MCDXLIII
Korean calendar	3776
Minguo calendar	469 before ROC; 民前469年
Nanakshahi calendar	−25
Thai solar calendar	1985–1986
Tibetan calendar	阳水狗年; (male Water-Dog); 1569 or 1188 or 416; — to —; 阴水猪年; (female Water-Pig); 1570 or 1189 or 417

Millennium:	2nd millennium
Centuries:	14th century; 15th century ; 16th century;
Decades:	1420s; 1430s; 1440s ; 1450s; 1460s;
Years:	1440; 1441; 1442; 1443 ; 1444; 1445; 1446;

Events

July 22 – Battle of St. Jakob an der Sihl (Old Zürich War): The forces of the city of Zürich are defeated, but the Swiss Confederacy have insufficient strength to besiege and take the city.
November 8 – Battle of Niš: John Hunyadi and the army of the Crusade of Varna defeat three armies of the Ottoman Empire, and capture the city of Niš in modern-day Serbia; Skanderbeg deserts the Ottoman camp and goes to Albania.
November 28 – Skanderbeg and his forces, rebelling against the Ottoman Empire, liberate Krujë, in Middle Albania, and raise the Albanian flag.

In Moldavia, the conflict between brothers and co-rulers Iliaș and Stephen II reignites, and Stephen captures Iliaș and blinds him, thus remaining sole ruler of the country.
Portuguese explorer Nuno Tristão penetrates the Arguin Gulf, off the west coast of Africa.
King Sejong the Great starts to crate Hangul, the native alphabet of the Korean language, with his scholars.
Vlad II Dracul begins his second term as ruler of Wallachia, succeeding Basarab II.
The Buddhist Zhihua Temple (智化寺) is built in Beijing, at the order of Wang Zhen, chief eunuch at the court of the Zhengtong Emperor of Ming Dynasty China.
A powerful earthquake destroys the Timișoara Fortress in the Kingdom of Hungary

January 16 – Erasmo of Narni, Italian mercenary (b. 1370)
January 28 – Robert le Maçon, Chancellor of France
February – Guidantonio da Montefeltro, count of Urbino (b. 1377)
March 24 – James Douglas, 7th Earl of Douglas (b. 1371)
April 12 – Henry Chichele, Archbishop of Canterbury^[3]
May – John II, Count of Nassau-Siegen^[4]
May 9 – Niccolò Albergati, Italian cardinal and diplomat (b. 1373)
June 5 – Ferdinand the Holy Prince of Portugal (b. 1402)
August 16 – Ashikaga Yoshikatsu, Japanese shōgun (b. 1434)
September 18 – Lewis of Luxembourg, Archbishop of Rouen
date unknown – Infante Diogo, Constable of Portugal
- Jelena Balšić, Serbian duchess (b. 1366)
probable – Zeami Motokiyo, Japanese actor and playwright (b. 1363)

^ Elizabeth Norton (September 15, 2010). Margaret Beaufort: Mother of the Tudor Dynasty. Amberley Publishing Limited. p. 17. ISBN 978-1-4456-0734-4.
^ Lives of the Popes: Illustrated Biographies of Every Pope from St Peter to the Present. Barnes & Noble Books. 1998. p. 197. ISBN 978-0-7607-0802-6.
^ Clayton J. Drees (2001). The Late Medieval Age of Crisis and Renewal, 1300-1500: A Biographical Dictionary. Greenwood Publishing Group. p. 103. ISBN 978-0-313-30588-7.
^ Becker, E. (1983) [1950]. Schloss und Stadt Dillenburg. Ein Gang durch ihre Geschichte in Mittelalter und Neuzeit. Zur Gedenkfeier aus Anlaß der Verleihung der Stadtrechte am 20. September 1344 herausgegeben (in German) (Neuauflage ed.). Dillenburg: Der Magistrat der Stadt Dillenburg. p. 12.