كان آخر تفشي للكوليرا في الولايات المتحدة بين عامي 1910-1911 عندما جلبت الباخرة مولتك بعض المصابين بالمرض إلى مدينة نيويورك القادمين من مدينة نابولي الإيطالية. قامت السلطات الصحية بعزل المصابين في جزيرة سوينبرن، والتي قد بنيت في القرن التاسع عشر بغرض جعلها للحجر الصحي. توفي أحد عشر شخصا، من بينهم عامل الرعاية الصحية في مستشفى الجزيرة.[1][4][5]
^ اب"More Cholera in Port". Washington Post. 10 أكتوبر 1910. مؤرشف من الأصل في 2013-02-21. اطلع عليه بتاريخ 2008-12-11. A case of cholera developed today in the steerage of the Hamburg-American liner Moltke, which has been detained at quarantine as a possible cholera carrier since Monday last. Dr. A.H. Doty, health officer of the port, reported the case tonight with the additional information that another cholera patient from the Moltke is under treatment at Swinburne Island.
^The Boston Medical and Surgical Journal. Massachusetts Medical Society. 1911. مؤرشف من الأصل في 2020-01-25. In New York, up to July 22, there were eleven deaths from cholera, one of the victims being an employee at the hospital on Swinburne Island, who had been discharged. The tenth was a lad, seventeen years of age, who had been a steerage passenger on the steamship, Moltke. The plan has been adopted of taking cultures from the intestinal tracts of all persons held under observation at Quarantine, and in this way it was discovered that five of the 500 passengers of the Moltke and Perugia, although in excellent health at the time, were harboring cholera microbes.