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Karnitina palmitoil transferase II

Karnitina palmitoil transferase II (CPT II) adalah enzim yang memiliki fungsi sebagai katalisator proses konjungasi asilkarnitin rantai panjang dan sangat panjang ke koenzim A setelah asilkarnitin dipindahkan ke dalam mitokondria.[1] Karnitina palmitoil transferase II berlokasi di membran dalam mitokondria.[2] Gen CPT 2 pada manusia terletak pada kromosom 1 (1p32) yang tersusun atas 3090 nukleotida serta terdiri 5 ekson yang dapat mengodekan rantai peptida protein enzim yang terdiri dari 658 asam amino.[3]

Daftar pustaka

  1. ^ Sun, Angela; Wang, Raymond Y.; Puliyanda, Dechu P. (2013). Rimoin, David; Pyeritz, Reed; Korf, Bruce (ed.). Chapter 63 - Cystic Diseases of the Kidney. Oxford: Academic Press. hlm. 1–33. doi:10.1016/b978-0-12-383834-6.00067-7. ISBN 978-0-12-383834-6. Pemeliharaan CS1: Status URL (link)
  2. ^ Sigauke, Ellen; Rakheja, Dinesh; Kitson, Kimberly; Bennett, Michael J. (2003). "Carnitine Palmitoyltransferase II Deficiency: A Clinical, Biochemical, and Molecular Review". Laboratory Investigation (dalam bahasa Inggris). 83 (11): 1543–1554. doi:10.1097/01.LAB.0000098428.51765.83. ISSN 1530-0307.
  3. ^ Yao, Min; Zhou, Ping; Qin, Yan-Yan; Wang, Li; Yao, Deng-Fu (2023-03-28). "Mitochondrial carnitine palmitoyltransferase-II dysfunction: A possible novel mechanism for nonalcoholic fatty liver disease in hepatocarcinogenesis". World Journal of Gastroenterology (dalam bahasa Inggris). 29 (12): 1765–1778. doi:10.3748/wjg.v29.i12.1765. PMC 10080702. PMID 37032731. Pemeliharaan CS1: DOI bebas tanpa ditandai (link)

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