At the town centre of Klang, the FT2 highway intersects with Jalan Langat FT5 at Simpang Lima Roundabout Interchange. As a result, the FT5 concurrents with the FT2 along Jambatan Kota before the FT5 route is diverted to Jalan Kapar FT5 at Simpang Tujuh Roundabout Interchange.^[3]

The FT2 highway becomes a controlled-access expressway starting from Berkeley Roundabout Interchange to Seputeh Interchange, where the controlled-access section is popularly known as the Federal Highway Route 2. The section of the Federal Highway FT2 from Berkeley Roundabout Interchange to Subang Airport Interchange is a tolled section managed by PLUS Malaysia Berhad, the operator of the nation's longest expressway, the North–South Expressway. The Federal Highway FT2 later becomes a limited-access arterial highway again after Seputeh Interchange, where it becomes Jalan Syed Putra. Jalan Syed Putra FT2 was concluded at Bulatan Kinabalu where it joins with Jalan Kinabalu FT1.^[4]

Meanwhile, the Kuala Lumpur–Kuantan Road begins as Jalan Pahang FT2 from Pahang Roundabout at Jalan Tun Razak. The FT2 road is later diverted to Jalan Gombak FT2/FT68 at Setapak Interchange. At Kampung Bandar Dalam Intersection, the FT2 route is once again diverted to Jalan Kampung Bandar Dalam FT2, while Jalan Gombak changes its route number to FT68. At Kampung Bandar Dalam Interchange, the FT2 concurrents with Duta–Ulu Klang Expressway E33/FT2 to Taman Greenwood, Batu Caves, then it concurrents with the Kuala Lumpur Middle Ring Road 2 (KL MRR2) FT28 from Taman Greenwood to Gombak North Interchange, before once again concurrents with the Kuala Lumpur–Karak Expressway E8/FT2 for its entire length.^[4]

At the end of the Karak Expressway at Karak Interchange, the Federal Route 2 is diverted as an ordinary 2-lane federal road while the Karak Expressway proceeds as the East Coast Expressway. The Federal Route 2 overlaps again at Kuantan with the Federal Route 3. The eastern terminus of the Federal Route 2 is at the Kuantan Port, where it meets with the Federal Route 3.^[1]

Before the advent of the Swettenham Parkway (now Sultan Iskandar Highway) which is now a part of the Kuala Lumpur Middle Ring Road 1 (KL MRR1), the FT2 road overlapped with Jalan Kinabalu FT1 and Jalan Kuching FT1 from Kinabalu Roundabout Interchange to PWTC Interchange, where the FT2 was detoured to Jalan Tun Razak and Jalan Pahang.^[4] However, after the completion of the Kuala Lumpur–Petaling Jaya Traffic Dispersal Scheme in 1983 that extended the KL MRR1 to Jalan Istana Interchange that linked the MRR1 with Jalan Syed Putra FT2, the FT2 ceased to concurrent with the FT1 and was detoured to Lebuhraya Sultan Iskandar (formerly Lebuhraya Mahameru) instead.^[5]

The Federal Route 2 begins as part of the earliest trunk road to Kuantan, Pahang from Benta, where the road was constructed as an extension of the Kuala Kubu Road from Kuala Kubu Bharu, Selangor to Kuala Lipis, Pahang. The 80-mile Kuala Kubu Road, which now becomes the entire section of the Federal Routes 55 and parts of Federal Route 218 and 8, was constructed by the Public Works Department (JKR) in 1887. The Benta–Kuantan Road, which now forms the entire section of the Federal Route 64 (Benta–Maran) and a part of the Federal Route 2 from Maran to Kuantan, was constructed in 1915. The Kuala Lumpur–Bentong section was constructed at the same time, followed by the Bentong–Temerloh section in 1928.^[6][7]

The Kuala Lumpur–Kuantan Road FT2 was concluded in 1955 when the final section from Temerloh to Maran was opened to traffic on 11 June 1955.^[8] The final section took a very long time to be completed due to rainy season, huge floods and swampy region, as well as the advances of the Imperial Japanese Army during the Second World War and the activities of the Malayan Communist Party terrorists during the Malayan Emergency. Construction began from 1925 to and was completed in 1955.^[8]

In 1971, the old Temerloh Bridge spanning across the Pahang River was collapsed due to the huge flood in Temerloh. As a result, the Public Works Department (JKR) constructed a 575-m replacement bridge known as the Sultan Ahmad Shah Bridge FT2 beside the old bridge.^[9] The Sultan Ahmad Shah Bridge was much higher than the old bridge, forming the first grade-separated Interchange in Pahang that was linked to the Federal Route 10. The new bridge project also included a new roadway that bypassed Temerloh and Mentakab, causing the former Temerloh–Mentakab section to be re-gazetted as the Federal Route 87.^[7] The construction of the Sultan Ahmad Shah Bridge was completed in 1974.^[9]

Meanwhile, the Kuala Lumpur–Klang Highway FT2 was opened to traffic on 14 January 1959.^[10] The highway was intended as a replacement of the existing road system known as Jalan Klang Lama, Persiaran Selangor, Jalan Sungai Rasau and Jalan Batu Tiga Lama, allowing speeds of up to 60 mph.^[8] As a result, Jalan Klang Lama was downgraded into Selangor State Road B14.^[5] The Kuala Lumpur–Klang Highway FT2 was later being upgraded into a controlled-access highway by replacing the former at-grade intersection with grade-separated interchanges, making the highway as the nation's first controlled-access expressway.^[11] The upgraded controlled-access highway is now known as the Federal Highway Route 2.

In the 1970s, a replacement segment for the narrow and winding section from Kuala Lumpur to Karak (known as Jalan Gombak) was constructed. The replacement section was known as the Kuala Lumpur–Karak Highway FT2, featuring the 914.4-m Genting Sempah Tunnel. The 75.2-km toll highway was constructed at the cost of RM136.4 million and was opened to traffic on 7 January 1978.^[12] As a result, the old Jalan Gombak was re-gazetted as the Federal Route 68. In 1994, the Kuala Lumpur–Karak Highway FT2 was upgraded to a full controlled-access expressway by twinning the entire section, including the construction of the second tunnel beside the existing Genting Sempah Tunnel for eastbound traffic. The upgrade works began in 1994 by MTD Prime and was completed in 1998.^[13] However, only 60 km of the 75-km highway forms the present-day Kuala Lumpur–Karak Expressway E8/FT2; the remaining 15 km forms a part of the Kuala Lumpur Middle Ring Road 2 (KL MRR2) FT28 and Duta–Ulu Klang Expressway E33.

The construction of the extension of the Kuala Lumpur–Karak Expressway E8/FT2, known as the East Coast Expressway, was first announced in 1994 when the expressway itself was still under upgrading works.^[13] Initially, the East Coast Expressway was supposed to be constructed under a different route number by a consortium consisting MMC Corporation Berhad (through its subsidiary, Projek Lebuhraya Timur Sdn. Bhd. (Pelita)), MTD Group and Malaysian Resource Corporation Berhad (MRCB),^[14] but was ultimately constructed by MTD Group in 2001 after the former consortium withdrew from the job due to the effects of the 亚洲金融风暴.^[15] The East Coast Expressway was opened to motorists on 1 August 2004, taking the role of the Federal Route 2 as the main east–west route from Kuala Lumpur to Kuantan.^[16] The expressway retained the E8 route number similar to the upgraded Kuala Lumpur–Karak Expressway E8/FT2, which was also operated by MTD Group (now ANIH Berhad).

Km	Exit	Interchange/Junctions[1]	To	Remarks
		Port Klang–Bulatan Simpang Lima	see also Persiaran Raja Muda Musa
		Klang Bulatan Simpang Lima–Bulatan Simpang Empat	see also Jalan Jambatan Kota
		Klang–Kuala Lumpur	see also Federal Highway
		Kuala Lumpur	see also Jalan Syed Putra Kuala Lumpur Middle Ring Road 1 Jalan Tuanku Abdul Rahman Genting Klang–Pahang Highway Jalan Gombak Jalan Kampung Bandar Dalam
		Kuala Lumpur–Gombak	see also Invalid type: AH Duta–Ulu Klang Expressway (old route to Greenwood Interchange at Route )
		Gombak–Gombak Utara	see also Invalid type: AH Kuala Lumpur Middle Ring Road 2
		Gombak Utara–Karak	see also Invalid type: AH Kuala Lumpur–Karak Expressway
		Karak-ECE	North C138 Jalan FELDA Mempaga FELDA Mempaga Pusat Serenti Mempaga East Invalid type: AH East Coast Expressway Kuala Terengganu Kuantan Lanchang	Interchange
		Taman Karak Jaya
		Taman Karak Indah
		Karak
	EXIT 230	Karak Simpang Pelangai Junctions	South Tampin Kuala Pilah Kuala Klawang Telemung	T-junctions
		Taman Seri Bentong
	EXIT 231	Kampung Lengkong Junctions	North C111 Jalan Lengkong C111 Kampung Lengkong	T-junctions
Bentong–Temerloh district border
	EXIT 232	Mempateh Junctions	North C115 Jalan Teris C115 Kampung Teris Kampung Balok FELDA Lakum Raub	T-junctions
		Lanchang '	North Jalan Lanchang Kampung Bolok Cempaka FELDA Lakum Raub Kuala Lipis Kuala Gandah Elephant Conservation Centre Invalid type: AH East Coast Expressway Kuala Lumpur Kuantan Kuala Terengganu	T-junctions
		Sungai Cermang bridge
		Kampung Sementih
		Kampung Rantau Panjang
		Kampung Woh
		Kampung Bongsu
		Kampung Sungai Kepung
		Desa Bakti
		Taman Mentakab Indah
		Kampung Batu Tiga
	EXIT 233	Mentakab (West) Junction	North Mentakab Jerantut Taman Negara East Coast Expressway Kuala Lumpur Kuantan Kuala Terengganu	T-junctions
		Mentakab–Temerloh	see also Mentakab–Temerloh Bypass
	EXIT 235	Temerloh Interchange	North Town centre Mentakab Jerantut Taman Negara Invalid type: AH East Coast Expressway Kuala Lumpur Kuantan Kuala Terengganu South Bera Teriang Bahau Gemas Bera Lake	Roundabout and Parcelo Interchange
		Temerloh Rest and Service Area		West bound
		Sungai Pahang Bridge Jambatan Sultan Ahmad Shah (Temerloh Bridge)
		Jalan Kampung Seberang	North C123 Jalan Kampung Seberang Kampung Seberang Batu Sawar Rantau Makmur	T-junctions
		Kampung Tebal
		Temerloh Restaurant and Rest Plaza	Petronas Maju Curry House Restaurant	East bound
		Taman Harapan
	EXIT 236	Hospital Sultan Haji Ahmad Shah Jalan Paya Luas	South C125 Jalan Paya Luas Kampung Paya Luas Kampung Paya Pulai Hospital Sultan Haji Ahmad Shah, Temerloh	T-junctions
	EXIT 237	Gunung Senyum Junction Jalan Padang Tenggala	West C123 Jalan Padang Tenggala Kampung Padang Tenggala C123 Batu Sawar C123 Rantau Makmur Gunung Senyum	T-junctions
		Kampung Jaya 3
		Kampung Jaya 5
		Paya Pulai
		Kampung Paya Pulai Tengah
		Kampung Batu Empat
		Jalan Kampung Guai	South Jalan Kampung Guai Kampung Guai Charuk Puting	T-junctions
		Kampung Paya Pulai
Temerloh–Maran district border
		Kampung Awah
	EXIT 238	Kampung Awah Junctions	North Jalan Bandar Pusat Jengka Bandar Pusat Jengka Invalid type: AH East Coast Expressway Kuala Lumpur Kuala Terengganu Kuantan	T-junctions
		Taman Awah Indah
		Awah
	EXIT 239	Jalan Pekan Sehari Kampung Awah Intersections	South Jalan Pekan Sehari Kampung Awah Pekan Sehari Kampung Awah	T-junctions
		Kampung Rantau Panjang
		Kampung Bukit Lada
	EXIT 240	Jalan Chenor Junctions	South C23 Jalan Chenor Chenor	T-junctions
		Kampung Jengka Batu Tiga Belas
		Sungai Jengka bridge
		Kampung Paya Pasir
		Sungai Leng
		Bukit Genting Rest Service Area & Paya Pasir Forest Reserve	Bukit Genting Rest Service Area & Paya Pasir Recreation Area
		Sungai Irok bridge
		Kampung Telut
		Sungai Jempul bridge
	EXIT 241	Pekan Tajau Junctions	North Jalan Bandar Pusat Jengka Timur Bandar Pusat Jengka South Jalan Kuala Jempul Kampung Kuala Jempul	T-junctions
		Seri Jengka Rest and Service Area
		Kampung Sentosa
		FELDA Bukit Tajau	FELDA Bukit Tajau	T-junctions
		Sungai Kemak
	EXIT 242	Jalan Lubuk Paku Junctions	South C21 Jalan Lubuk Paku Lubuk Paku	T-junctions
	EXIT 243	Sungai Jerik Junctions	North Jerantut Bandar Pusat Jengka	T-junctions
		Maran	Maran town centre Maran District and Land Office Maran District Mosque
		Maran	Southeast C133 Jalan Kampung Bak Bak Kampung Bak Bak
	EXIT 244	Serangkam Junction	South C133 Jalan Serangkam Kampung Bak-Bak Kampung Serangkam	T-junctions
		Sungai Maran bridge
		Taman Maran Impian
	EXIT 245	Maran Junction Maran-ECE	Invalid type: AH East Coast Expressway West Kuala Lumpur Temerloh Chenor Template:Parking layby signs Maran Layby East Kuala Terengganu Kuantan Sri Jaya	T-junctions
		Kampung Bentung
		Kampung Teras
		Sungai Luit bridge
		Kampung Luit
		Jalan Ulu Luit	North C135 Jalan Ulu Luit Kampung Ulu Luit	T-junctions
		Kampung Kertam
		FELDA New Zealand	North 1485 Jalan FELDA New Zealand FELDA New Zealand	T-junctions
		Sri Jaya
	EXIT 246	Sri Jaya Junctions Sri Jaya-ECE	Invalid type: AH East Coast Expressway West Kuala Lumpur Temerloh Maran East Kuala Terengganu Kuantan Gambang Gambang Rest and Service Area	T-junctions
	EXIT 247	Jalan Belimbing Junctions	South C19 Jalan Belimbing Belimbing Tasik Chini	T-junctions
		Kampung Batu 37
Maran–Kuantan district border
		Kampung Paya Bungor
		Lake Paya Bungor	Lake Paya Bungor Template:Fishing area sign V
		Kampung Paya Merbau
		Kampung Gelugur
		Kampung Berkelah
		Sungai Lepar bridge
		Hutan Lipur Berkelah
		Sungai Berkelah bridge
		Kampung Batu Licin
		Kampung Semugi
		Kampung Pohol
		Paya Besar
		Sungai Belat
		Gambang
		Gambang–Kuantan	see also Gambang–Kuantan Highway
	EXIT 251	Padang Lalang Junctions	East Jalan Teluk Sisik Teluk Cempedak South Tanjung Lumpur Highway Tanjung Lumpur Invalid type: AH Pekan Invalid type: AH Johor Bahru Pantai Sepat	Junctions
	EXIT 2--	Jalan Haji Ahmad Junctions	Northwest Jalan Haji Ahmad Galing Semambu Jabur	T-junctions
		Sungai Galing bridge
	EXIT 2--	Jalan Air Putih Junctions	North Jalan Air Putih Air Putih	T-junctions
		Taman Beserah
		Sungai Alor Akar bridge
	EXIT 2--	Alor Akar Junctions	Northwest Jalan Semambu Semambu Jabur South Jalan Tengku Muhamad Teluk Cempedak	Junctions
		Kampung Ceti	Kampung Pelindung	T-junctions
		Kampung Alur Tuan Haji
		Kampung Rumbia	Kampung Rumbia Kampung Pasir Garam Kampung Bugis	T-junctions
		Kampung Jeram Beserah
		Jalan Stesen Satelit Bumi Kuantan	West Jalan Stesen Satelit Bumi Kuantan Kuantan Satellite Earth Station Taman Beserah Taman Perumahan Bukit Beserah	T-junctions
		Sungai Beserah bridge
		Kampung Tuan
		Beserah	Beserah Beach V	T-junctions
		Kampung Batu Hitam	Batu Hitam Beach V	T-junctions
		Kampung Sungai Karang	Sungai Karang Beach V	T-junctions
		Pengkalan Damar	West Jalan Pengkalan Damar Pengkalan Damar	T-junctions
		Sungai Karang bridge
		Swiss Garden Resort
		Duta Vista Resort
		Kampung Balok Baru
		Kampung Balok
		Sungai Balok bridge
		Kampung Seberang Balok
		Kampung Berahi
	EXIT 279	Kuantan Bypass Junctions	West Invalid type: AH Kuantan Bypass Gebeng Kemaman Kuala Terengganu Cherating	T-junctions
		Kampung Selamat
	EXIT 280	Kuantan Port Junctions	Kuantan Port Industrial Area Kemaman Kuala Terengganu	T-junctions
Kuantan Port Lembaga Pelabuhan Kuantan (LPKtn) and Kuantan Port Consortium Sdn Bhd border limit
	EXIT 281	Pengorak Junctions	Northeast Jalan Tanjung Gelang Tanjung Gelang TLDM Tanjung Gelang Naval Base	T-junctions
		Lembaga Pelabuhan Kuantan (LPKtn) flat quarters
		Kuantan Port Customs checkpoint	海关	U-Turn
Kuantan Port Customs checkpoint 海关 海关
		Kuantan Port