Perfenazin

Perfenazin
Farmakokinetik veri
Biyoyararlanım%40
MetabolizmaHepatik
Eliminasyon yarı ömrü8-12 (20'ye çıkabilir) saat
Tanımlayıcılar
CAS Numarası
PubChem CID
DrugBank
CompTox Bilgi Paneli (EPA)
ECHA Bilgi Kartı100.000.346 Bunu Vikiveri'de düzenleyin
Kimyasal ve fiziksel veriler
FormülC21H26ClN3OS
Mol kütlesi403.97

Perfenazin tipik antipsikotik bir ilaçtır. Kimyasal olarak piperazinil fenotiyazin olarak sınıflandırılır.

Perfenazin, dopamin-2 (D2) reseptöründe klorpromazinden kabaca on kat daha güçlüdür;[1] bu nedenle perfenazin orta etkili bir antipsikotik olarak kabul edilir.[2][3]

Kaynakça

  1. ^ "Chlorpromazine and allied phenothiazine derivatives". British Medical Journal. 2 (5197): 522-5. August 1960. doi:10.1136/bmj.2.5197.522. PMC 2097091 $2. PMID 14436902. 
  2. ^ "Time to discontinuation of atypical versus typical antipsychotics in the naturalistic treatment of schizophrenia". BMC Psychiatry. 6: 8. February 2006. doi:10.1186/1471-244X-6-8. PMC 1402287 $2. PMID 16504026. 
  3. ^ "Treatment of psychotic disorders". Psychotic disorders. Practical Guides in Psychiatry. Lippincott Williams & Wilkins. 2007. s. 88. ISBN 978-0-7817-8543-3. 9 Ocak 2020 tarihinde kaynağından arşivlendi. Erişim tarihi: 22 Haziran 2009. 

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