Glomerüler filtrasyon oranı

Şematik bir nefron. Nefron tarafından sıvı ve elektrolitlerin işlenmesine ilişkin temel fizyolojik mekanizmalar - filtrasyon, sekresyon, yeniden emilim ve boşaltım - etiketlenmiştir.

Böbrek fonksiyonları arasında kan basıncı, asit-baz ve sıvı dengesinin yanı sıra sodyum, potasyum ve diğer elektrolitlerin düzenlenmesi; toksinlerin temizlenmesi ; glikoz, amino asitler ve diğer küçük moleküllerin emilimi; eritropoietin yapımı gibi çeşitli hormonların üretimi; ve D vitamini aktivasyonu bulunur.

Böbrek fonksiyonunun ölçütlerinden biri glomerüler filtrasyon hızıdır (GFR). Glomerüler filtrasyon hızı, filtre edilen sıvının böbrek boyunca akış hızını tanımlar. Kreatinin klirens oranı (Cr veya CrCl), birim zamanda kreatinin'den temizlenen kan plazması hacmidir ve GFR'ye yaklaşık bir ölçüdür. Hem GFR hem de C Cr, kan ve idrardaki maddelerin karşılaştırmalı ölçümleriyle doğru bir şekilde hesaplanabilir veya sadece bir kan testi sonucu kullanılarak tahmin edilebilir (eGFR ve eC Cr) . Bu testlerin sonuçları, böbreklerin boşaltım fonksiyonunu değerlendirmek için kullanılır. Kronik böbrek hastalığının evrelemesi, GFR yanı sıra albüminüri ve böbrek hastalığı nedenine dayandırılır.[1]

Vücut yüzey alanına göre ayarlanan normal GFR aralığı erkeklerde 100–130 ortalama 125 mL/dk/ 1,73m2 ve 40 yaşından küçük kadınlarda 90–120 mL/dk/ 1,73m2'dir. Çocuklarda inülin klerensi ile ölçülen GFR her iki cinsiyette de 2 yaşına kadar 110 mL/dk/1,73 m2 olup, daha sonra giderek azalır. 40 yaşından sonra, GFR yaşla birlikte kademeli olarak yılda 0.4-1.2 mL/dak azalır.

Tahmini GFR (eGFR), GFR'nin rutin değerlendirmesi için klinik uygulama kılavuzları ve düzenleyici kurumlar tarafından tavsiye edilirken, ölçülen GFR (mGFR) doğrulayıcı bir test olarak önerilmektedir.[2]

Ayrıca bakınız

Kaynakça

  1. ^ Stevens (4 Haziran 2013). "Evaluation and management of chronic kidney disease: synopsis of the kidney disease: improving global outcomes 2012 clinical practice guideline". Annals of Internal Medicine. 158 (11): 825-830. doi:10.7326/0003-4819-158-11-201306040-00007. ISSN 1539-3704. PMID 23732715. 
  2. ^ Levey AS (2020). "Measured and estimated glomerular filtration rate: current status and future directions". Nat Rev Nephrol. 16 (1): 51-64. doi:10.1038/s41581-019-0191-y. PMID 31527790. 

Read other articles:

Bilderberg Hotel Wientjes, Zwolle Bilderberg adalah jaringan hotel dan restoran yang berdiri di Belanda. Saat ini Bilderberg mengoperasikan 20 hotel di Belanda. Namanya menjadi asal usul nama Bilderberg Group yang mengadakan pertemuan pertamanya di Bilderberg Hotel di Oosterbeek. Hotel Hotel-hotel ternama milik jaringan ini adalah: Bilderberg Hotel, Oosterbeek Doorwerth Castle, Doorwerth Restoran ternama milik jaringan ini adalah: De Kromme Dissel, Heelsum De Kersentuin, di Bilderberg Garden ...

 

2015 Indian Malayalam film The ReporterTheatrical release posterDirected byVenugopanWritten byS. Suresh BabuProduced byK. R. BaburajRaju PanayamkulamStarringKailashSamuthirakaniAnanyaAbhinayaCinematographyAlagappan NEdited bySujoy JosephMusic bySharrethProductioncompanySarayu MoviesRelease date 6 March 2015 (2015-03-06) CountryIndiaLanguageMalayalam The Reporter is an Indian Malayalam mystery thriller-romance film directed by Venugopan. The film stars Kailash, Samuthirakani, ...

 

Sophia RoganSophia Rogan, Miss Grand Indonesia 2021.LahirSophie Louise Rogan28 Februari 2002 (umur 22)Denpasar, Bali, IndonesiaPendidikan Austalian Independent School Bali (2019 - 2020) International School of Macao (2014 - 2020) British School Manila (2012 - 2014) AlmamaterCondé Nast College of Fashion & DesignPekerjaanModelPenyanyiPemegang gelar kontes kecantikanTinggi182 cm (6 ft 0 in)Pemenang kontes kecantikanGelarMiss Grand Indonesia 2021Warna rambutCokelat tuaW...

Norwegian road cyclist Kristian KulsetKulset in 2020Personal informationFull nameKristian Marthinsen KulsetBorn (1995-10-01) 1 October 1995 (age 28)Oslo, NorwayHeight1.88 m (6 ft 2 in)Team informationCurrent teamRetiredDisciplineRoadRoleRiderAmateur teams2012–2013Bærum OCK Junior2014–2016Ringerike SK Professional team2016–2022Team Ringeriks–Kraft[1] Kristian Marthinsen Kulset (born 1 October 1995) is a Norwegian former cyclist, who competed as a ...

 

Tatiana Santo Domingo Données clés Naissance 24 novembre 1983 (40 ans) New York (État de New York, États-Unis) Nationalité ColombienneMonégasqueAméricaine Pays de résidence MonacoSuisseFranceRoyaume-Uni Profession Femme d'affaires Activité principale Créatrice de mode Formation École internationale de GenèvePensionnat à Fontainebleau Ascendants Julio Mario Santo Domingo BragaVera Rechulski Conjoint Andrea Casiraghi Descendants Alexandre CasiraghiIndia CasiraghiMaximilian Ca...

 

Danish brewer, merchant and shipowner Hans Peder KofoedKofoed painted by J.A. BechBornC. (1743-10-01)1 October 1743Svaneke, Bornholm, DenmarkDied3 January 1812(1812-01-03) (aged 68)Copenhagen, DenmarkNationalityDanishOccupation(s)Industrialist, merchant, ship owner, ship builder, landowner, brewerAwardsGrand Cross of the Dannebrog Hans Peder Kofoed (c. 1 October 1743 – 3 January 1812) was a Danish brewer, merchant and shipowner who became wealthy from trade on the Danish West Indie...

Language family For other uses, see Pontic languages. This article needs additional citations for verification. Please help improve this article by adding citations to reliable sources. Unsourced material may be challenged and removed.Find sources: Northwest Caucasian languages – news · newspapers · books · scholar · JSTOR (January 2010) (Learn how and when to remove this message) Northwest CaucasianWest CaucasianAbkhazo–CircassianAbkhaz–AdygheanNo...

 

Сибирский горный козёл Научная классификация Домен:ЭукариотыЦарство:ЖивотныеПодцарство:ЭуметазоиБез ранга:Двусторонне-симметричныеБез ранга:ВторичноротыеТип:ХордовыеПодтип:ПозвоночныеИнфратип:ЧелюстноротыеНадкласс:ЧетвероногиеКлада:АмниотыКлада:СинапсидыКла�...

 

Голубянки Самец голубянки икар Научная классификация Домен:ЭукариотыЦарство:ЖивотныеПодцарство:ЭуметазоиБез ранга:Двусторонне-симметричныеБез ранга:ПервичноротыеБез ранга:ЛиняющиеБез ранга:PanarthropodaТип:ЧленистоногиеПодтип:ТрахейнодышащиеНадкласс:ШестиногиеКласс...

Species of bird Common ringed plover AdultCalls recorded in Norfolk, England Conservation status Least Concern  (IUCN 3.1)[1] Scientific classification Domain: Eukaryota Kingdom: Animalia Phylum: Chordata Class: Aves Order: Charadriiformes Family: Charadriidae Genus: Charadrius Species: C. hiaticula Binomial name Charadrius hiaticulaLinnaeus, 1758 The common ringed plover or ringed plover (Charadrius hiaticula) is a small plover that breeds across much of northern Eurasia, a...

 

41°40′00″N 26°34′00″E / 41.66666667°N 26.56666667°E / 41.66666667; 26.56666667 إيالة أدرنة إيالة أدرنة عام 1850   إحداثيات: 41°40′00″N 26°34′00″E / 41.66666667°N 26.56666667°E / 41.66666667; 26.56666667   البلد الدولة العثمانية   1826 – 1867 التقسيم الإداري إيالة العاصمة أدرنة تعديل مصدري - تعديل ...

 

مقام خادم صلاح الدين تقديم البلد  فلسطين مدينة بلدة كفل حارس، محافظة سلفيت إحداثيات 32°07′07″N 35°09′25″E / 32.118617°N 35.15695°E / 32.118617; 35.15695   نوع مقام وضريح تصنيف ديني الموقع الجغرافي تعديل مصدري - تعديل   مقام خادم صلاح الدين هو أحد المقامات الإسلامية في بلدة كفل ...

English astronomer (1823–1895) For other people with the same name, see John Hind. John Russell HindJohn Russell Hind c. 1860sBorn(1823-05-12)12 May 1823NottinghamDied23 December 1895(1895-12-23) (aged 72)Twickenham, LondonKnown forDiscovery of asteroids and variable starsAwardsLalande Prize (1847, 1850–1854)Gold Medal of the Royal Astronomical Society (1853)Royal Medal (1855) John Russell Hind FRS FRSE LLD (12 May 1823 – 23 December 1895) was an English astronomer. Life and w...

 

This article is about the district. For its eponymous headquarters, see Bishnupur, Manipur. District of Manipur in IndiaBishnupur districtDistrict of ManipurLoktak LakeLocation in ManipurCoordinates: 24°38′N 93°46′E / 24.633°N 93.767°E / 24.633; 93.767Country IndiaStateManipurHeadquartersBishnupurArea • Total496 km2 (192 sq mi)Population (2011) • Total237,399 • Density480/km2 (1,200/sq mi)Languag...

 

Spanish languageA manuscript of the Cantar de mio Cid, 13th century Overview Pronunciation stress Orthography Names History Old Middle Influences Grammar Determiners Nouns gender Pronouns personal object Adjectives Prepositions Verbs conjugation irregular verbs Dialects Andalusian Andean Argentine Belizean Bolivian Canarian Caribbean Central American Chilean Colombian Costa Rican Cuban Dominican Ecuadorian Equatoguinean Guatemalan Honduran Mexican Murcian New Mexican Nicaraguan Paraguay Panam...

Painting by Camille Pissarro A Cowherd at Valhermeil, Auvers-sur-OiseArtistCamille PissarroYear1874MediumOil on canvasMovementImpressionismDimensions54.9 cm × 92.1 cm (21.6 in × 36.3 in)LocationMetropolitan Museum of Art, New York A Cowherd at Valhermeil, Auvers-sur-Oise is an 1874 painting by Danish-French artist Camille Pissarro.[1] Done in oil on canvas, the work depicts the hamlet of Valhermeil in Auvers-sur-Oise, France, near Pontoise w...

 

Election in South Carolina Main article: 1812 United States presidential election 1812 United States presidential election in South Carolina ← 1808 October 30 – December 2, 1812 1816 →   Nominee James Madison Party Democratic-Republican Home state Virginia Running mate Elbridge Gerry Electoral vote 11 Percentage 100% President before election James Madison Democratic-Republican Elected President James Madison Democratic-Republican Elections in South...

 

City in California, United States For other places in California named Mountain View, see Mountain View (disambiguation). City in California, United StatesMountain View, CaliforniaCityCity Hall & Performing Arts Center FlagSealLocation within Santa Clara CountyMountain View city map, California, U.S.Coordinates: 37°23′10″N 122°05′02″W / 37.38611°N 122.08389°W / 37.38611; -122.08389CountryUnited StatesStateCaliforniaCountySanta ClaraIncorporatedNovember ...

Para otros usos de este término, véase Valladolid (desambiguación). Valladolid Provincia de España De izquierda a derecha y de arriba abajo: Castillo de Peñafiel, canal de Castilla, paisaje típico, un pinar, centro de un pueblo castellano, Castillo de La Mota y una bodega. BanderaEscudo Coordenadas 41°35′00″N 4°40′00″O / 41.583333333333, -4.6666666666667Capital ValladolidIdioma oficial CastellanoEntidad Provincia de España • País  España �...

 

Danish politician (born 1984) Pernille SkipperMPPolitical spokesperson of the Red–Green AllianceIn office4 May 2016 – 10 February 2021Preceded byJohanne Schmidt-NielsenSucceeded byMai VilladsenMember of the FolketingIn office15 September 2011 – 10 February 2021ConstituencyCopenhagen (from 2019)Fyn (2011—2019) Personal detailsBorn (1984-07-10) 10 July 1984 (age 40)Aalborg, DenmarkPolitical partyRed–Green AllianceSpouse(s)Oliver Routhe Skov(m. 2015)Alma materUni...