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Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Urejna karboksilaza
Urejna karboksilaza
Identifikatori
EC broj	6.3.4.6
CAS broj	9058-98-4
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Urejna karboksilaza (EC 6.3.4.6, ureaza (ATP hidrolizacija), urejna karboksilaza (hidrolizacija), ATP-urejna amidolijaza, urejna amidolijaza, UALaza, UCA) je enzim sa sistematskim imenom ureja:karbon-dioksid ligaza (formira ADP).^[1]^[2]^[3]^[4] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + ureja + HCO₃^-

\rightleftharpoons

ADP + fosfat + ureja-1-karboksilat

Ovaj enzim je biotinilni protein.

Reference

^ Roon, R.J. & Levenberg, B. (1970). „ATP-Urea amidolyase (ADP) (Candida utilis)”. Methods Enzymol. 17A: 317—324.
^ Roon, R.J. & Levenberg, B. (1972). „Urea amidolyase. I. Properties of the enzyme from Candida utilis”. J. Biol. Chem. 247: 4107—4113. PMID 4556303.
^ Sumrada, R.A. & Cooper, T.G. (1982). „Urea carboxylase and allophanate hydrolase are components of a multifunctional protein in yeast”. J. Biol. Chem. 257: 9119—9127. PMID 6124544.
^ Kanamori, T., Kanou, N., Atomi, H. and Imanaka, T. (2004). „Enzymatic characterization of a prokaryotic urea carboxylase”. J. Bacteriol. 186: 2532—2539. PMID 15090492.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Urea+carboxylase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Roon, R.J. & Levenberg, B. (1970). „ATP-Urea amidolyase (ADP) (Candida utilis)”. Methods Enzymol. 17A: 317—324.

[2] Roon, R.J. & Levenberg, B. (1972). „Urea amidolyase. I. Properties of the enzyme from Candida utilis”. J. Biol. Chem. 247: 4107—4113. PMID 4556303.

[3] Sumrada, R.A. & Cooper, T.G. (1982). „Urea carboxylase and allophanate hydrolase are components of a multifunctional protein in yeast”. J. Biol. Chem. 257: 9119—9127. PMID 6124544.

[4] Kanamori, T., Kanou, N., Atomi, H. and Imanaka, T. (2004). „Enzymatic characterization of a prokaryotic urea carboxylase”. J. Bacteriol. 186: 2532—2539. PMID 15090492.

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