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Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

CTP sintaza
CTP sintaza
	CTP sintetaza tetramer, Human
Identifikatori
EC broj	6.3.4.2
CAS broj	9023-56-7
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

CTP sintaza (EC 6.3.4.2, UTP—amonijak ligaza, citidin trifosfatna sintetaza, uridin trifosfatna aminaza, citidin 5'-trifosfatna sintetaza) je enzim sa sistematskim imenom UTP:amonijak ligaza (formira ADP).^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + UTP + NH₃

\rightleftharpoons

ADP + fosfat + CTP

Glutamin može da zameni NH₃.

Reference

^ Lieberman, I. (1956). „Enzymatic amination of uridine triphosphate to cytidine triphosphate”. J. Biol. Chem. 222: 765—775. PMID 13367044.
^ Long, C.W., Levitzki, A., Houston, L.L and Koshland, D.E., Jr. (1969). „Subunit structures and interactions of CTP synthetase”. Fed. Proc. 28: 342—342.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

CTP+synthase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Lieberman, I. (1956). „Enzymatic amination of uridine triphosphate to cytidine triphosphate”. J. Biol. Chem. 222: 765—775. PMID 13367044.

[2] Long, C.W., Levitzki, A., Houston, L.L and Koshland, D.E., Jr. (1969). „Subunit structures and interactions of CTP synthetase”. Fed. Proc. 28: 342—342.

[1]

[2]