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PMC	članci
PubMed	članci
NCBI	proteini

Saharopepsin
Saharopepsin
Identifikatori
EC broj	3.4.23.25
CAS broj	37228-80-1
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Saharopepsin (EC 3.4.23.25, kvašćana endopeptidaza A, Saccharomyces aspartinska proteinaza, aspartinska proteinaza yscA, proteinaza A, proteinaza yscA, kvašćana proteinaza A, Saccharomyces cerevisiae aspartinska proteinaza A, kvašćana proteinaza A, PRA) je enzim.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

Hidroliza proteina sa širokom specifičnošću za peptidne veze. Razlaže se -Leu-Leu-Val-Tyr veza u sintetičnim supstratime. Ne dolazi do reakcije na estrima Tyr ili Arg

Ovaj enzim je prisutan u vakuolama pekarskog kvasca (Saccharomyces cerevisiae).

Reference

^ Hata, T., Hayashi, R. and Dot, E. (1967). „Purification of yeast proteinases. Part III. Isolation and physicochemical properties of yeast proteinase A and C”. Agric. Biol. Chem. 31: 357—367.
^ Meussdoerffer, F., Tortora, P. and Holzer, H. (1980). „Purification and properties of proteinase A from yeast”. J. Biol. Chem. 255: 12087—12093. PMID 7002931.
^ Ammerer, G., Hunter, C.P., Rothman, J.H., Saari, G.C., Valls, L.A. and Stevens, T.H. (1987). „PEP4 gene of Saccharomyces cerevisiae encodes proteinase A, a vacuolar enzyme required for processing of vacuolar precursors”. Mol. Cell. Biol. 6: 2490—2499. PMID 3023936.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Saccharopepsin на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Hata, T., Hayashi, R. and Dot, E. (1967). „Purification of yeast proteinases. Part III. Isolation and physicochemical properties of yeast proteinase A and C”. Agric. Biol. Chem. 31: 357—367.

[2] Meussdoerffer, F., Tortora, P. and Holzer, H. (1980). „Purification and properties of proteinase A from yeast”. J. Biol. Chem. 255: 12087—12093. PMID 7002931.

[3] Ammerer, G., Hunter, C.P., Rothman, J.H., Saari, G.C., Valls, L.A. and Stevens, T.H. (1987). „PEP4 gene of Saccharomyces cerevisiae encodes proteinase A, a vacuolar enzyme required for processing of vacuolar precursors”. Mol. Cell. Biol. 6: 2490—2499. PMID 3023936.

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