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Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Pro-opiomelanokortinski konvertujući enzim
Pro-opiomelanokortinski konvertujući enzim
Identifikatori
EC broj	3.4.23.17
CAS broj	80891-34-5
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Pro-opiomelanokortinski konvertujući enzim (EC 3.4.23.17, prohormon konvertujući enzim, pro-opiomelanokortin-konvertujući enzim, proopiomelanokortinska proteinaza, PCE) je enzim.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

Odvajanje parova baznih ostataka u pojedinim prohormonima, bilo između njih, ili na karboksilnoj strani

Ovaj za membranu-vezani enzim je izolovan iz goveđe hipofize.

Reference

^ Loh, Y.P., Parish, D.C. and Tuteja, R. (1985). „Purification and characterization of a paired basic residue-specific pro-opiomelanocortin converting enzyme from bovine pituitary intermediate lobe secretory vesicles”. J. Biol. Chem. 260: 7194—7205. PMID 2987247.
^ Loh, Y.P. (1986). „Kinetic studies on the processing of human β-lipotropin by bovine pituitary intermediate lobe pro-opiomelanocortin-converting enzyme”. J. Biol. Chem. 261: 11949—11955. PMID 3017955.
^ Estivariz, F.E., Birch, N.P. and Loh, Y.P. (1989). „Generation of Lys-γ3-melanotropin from pro-opiomelanocortin1-77 by a bovine intermediate lobe secretory vesicle membrane-associated aspartic protease and purified pro-opiomelanocortin converting enzyme”. J. Biol. Chem. 264: 17796—17801. PMID 2553692.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Pro-opiomelanocortin+converting+enzyme на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Loh, Y.P., Parish, D.C. and Tuteja, R. (1985). „Purification and characterization of a paired basic residue-specific pro-opiomelanocortin converting enzyme from bovine pituitary intermediate lobe secretory vesicles”. J. Biol. Chem. 260: 7194—7205. PMID 2987247.

[2] Loh, Y.P. (1986). „Kinetic studies on the processing of human β-lipotropin by bovine pituitary intermediate lobe pro-opiomelanocortin-converting enzyme”. J. Biol. Chem. 261: 11949—11955. PMID 3017955.

[3] Estivariz, F.E., Birch, N.P. and Loh, Y.P. (1989). „Generation of Lys-γ3-melanotropin from pro-opiomelanocortin1-77 by a bovine intermediate lobe secretory vesicle membrane-associated aspartic protease and purified pro-opiomelanocortin converting enzyme”. J. Biol. Chem. 264: 17796—17801. PMID 2553692.

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