PROFILPELAJAR.COM

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Prepilinska peptidaza
Prepilinska peptidaza
Identifikatori
EC broj	3.4.23.43
CAS broj	202833-59-8
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Prepilinska peptidaza (EC 3.4.23.43) je enzim.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

Tipično dolazi do razlaganja -Gly-Phe- veze čime se oslobađa N-terminalni, bazni peptid sa 5-8 ostataka sa tipa IV prepilina, i zatim se N-metiliše nova N-terminal amino grupa, pri čemu je metilni donor S-adenozil-L-metionin

Ovaj enzim je prisutan u mnogim vrstama bakterije Carry pili.

Reference

^ Lory, S. & Strom, M.S. (1997). „Structure-function relationship of type-IV prepilin peptidase of Pseudomonas aeruginosa - A review”. Gene. 192: 117—121. PMID 9224881.
^ LaPointe, C.F. & Taylor, R.K. (2000). „The type 4 prepilin peptidases comprise a novel family of aspartic acid proteases”. J. Biol. Chem. 275: 1502—1510. PMID 10625704.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.

Spoljašnje veze

Prepilin+peptidase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Lory, S. & Strom, M.S. (1997). „Structure-function relationship of type-IV prepilin peptidase of Pseudomonas aeruginosa - A review”. Gene. 192: 117—121. PMID 9224881.

[2] LaPointe, C.F. & Taylor, R.K. (2000). „The type 4 prepilin peptidases comprise a novel family of aspartic acid proteases”. J. Biol. Chem. 275: 1502—1510. PMID 10625704.

[1]

[2]