OR2C1

Olfaktorni receptor, familija 2, potfamilija C, član 1
Identifikatori
Simboli OR2C1; OLFmf3; OR2C2P
Vanjski ID MGI106182 HomoloGene7459 GeneCards: OR2C1 Gene
Pregled RNK izražavanja
podaci
Ortolozi
Vrsta Čovek Miš
Entrez 4993 18312
Ensembl ENSG00000168158 ENSMUSG00000059043
UniProt O95371 P23275
RefSeq (mRNA) NM_012368.2 NM_008762.2
RefSeq (protein) NP_036500.2 NP_032788.2
Lokacija (UCSC) Chr 16:
3.41 - 3.41 Mb
Chr 16:
3.84 - 3.84 Mb
PubMed pretraga [1] [2]

Olfaktorni receptor 2C1 je protein koji je kod ljudi kodiran OR2C1 genom.[1][2]

Olfaktorni receptori formiraju interakcije sa molekulima mirisa u nosu, čime se inicira neuronski respons koji izaziva percepciju mirisa. Oni su odgovorni za prepoznavanje i G proteinima posredovanu transdukciju mirisnih signala. Proteini olfaktornih receptora su članovi velike familije G protein spregnutih receptora (GPCR). Poput mnogih receptora za neurotransmitere i hormone, olfaktorni receptori imaju strukturu 7-transmembranskog domena. Oni su kodirani genima sa jednim eksonom. Geni olfaktornih receptora su najveća familija genoma. Nomenklatura gena i proteina olfaktornih receptora je nezavisna od drugih organizama.[2]

Reference

  1. ^ Centola M, Chen X, Sood R, Deng Z, Aksentijevich I, Blake T, Ricke DO, Chen X, Wood G, Zaks N, Richards N, Krizman D, Mansfield E, Apostolou S, Liu J, Shafran N, Vedula A, Hamon M, Cercek A, Kahan T, Gumucio D, Callen DF, Richards RI, Moyzis RK, Doggett NA, Collins FS, Liu PP, Fischel-Ghodsian N, Kastner DL (1999). „Construction of an ∼700-kb Transcript Map Around the Familial Mediterranean Fever Locus on Human Chromosome 16p13.3”. Genome Res. 8 (11): 1172—91. PMC 310791Слободан приступ. PMID 9847080. doi:10.1101/gr.8.11.1172. 
  2. ^ а б „Entrez Gene: OR2C1 olfactory receptor, family 2, subfamily C, member 1”. 

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