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Metanol—5-hidroksibenzimidazolilkobamid Co-metiltransferaza
Metanol—5-hidroksibenzimidazolilkobamid Co-metiltransferaza
Identifikatori
EC broj	2.1.1.90
CAS broj	86611-98-5
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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NCBI	proteini

Metanol—5-hidroksibenzimidazolilkobamid Co-metiltransferaza (EC 2.1.1.90, metanol kobalaminska metiltransferaza, metanol:5-hidroksibenzimidazolilkobamidna metiltransferaza, MT 1 (nespecifična), metanol 5-hidroksibenzimidazolilkobamidna Co-metiltransferaza, mtaB (gen)) je enzim sa sistematskim imenom metanol:5-hidroksibenzimidazolilkobamid Co-metiltransferaza.^[1]^[2] Ovaj enzim katalizuje sledeću hemijsku reakciju

metanol+ [Co(I) metanol-specifični korinoidni protein]

\rightleftharpoons

[metil-Co(III) metanol-specifični korinoidni protein] + H₂O

Enzim, koji katalizuje transfer metil grupa sa metanola na metanol-specifični korinoidni protein (MtaC), učestvuje u metanogenezi koristeći metanol.

Reference

^ van der Meijden, P., te Brömmelstroet, B.W., Poirot, C.M., van der Drift, C. and Vogels, G.D. (1984). „Purification and properties of methanol:5-hydroxybenzimidazolylcobamide methyltransferase from Methanosarcina barkeri”. J. Bacteriol. 160: 629—635. PMID 6438059.
^ Sauer, K. & Thauer, R.K. (1999). „Methanol:coenzyme M methyltransferase from Methanosarcina barkeri – substitution of the corrinoid harbouring subunit MtaC by free cob(I)alamin”. Eur. J. Biochem. 261: 674—681. PMID 10215883.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Methanol-corrinoid+protein+Co-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] van der Meijden, P., te Brömmelstroet, B.W., Poirot, C.M., van der Drift, C. and Vogels, G.D. (1984). „Purification and properties of methanol:5-hydroxybenzimidazolylcobamide methyltransferase from Methanosarcina barkeri”. J. Bacteriol. 160: 629—635. PMID 6438059.

[2] Sauer, K. & Thauer, R.K. (1999). „Methanol:coenzyme M methyltransferase from Methanosarcina barkeri – substitution of the corrinoid harbouring subunit MtaC by free cob(I)alamin”. Eur. J. Biochem. 261: 674—681. PMID 10215883.

[1]

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