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Linoleat 11-lipoksigenaza
Linoleat 11-lipoksigenaza
Identifikatori
EC broj	1.13.11.45
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
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PMC	članci
PubMed	članci
NCBI	proteini

Linoleat 11-lipoksigenaza (EC 1.13.11.45, linoleatna dioksigenaza, manganska lipoksigenaza) je enzim sa sistematskim imenom linoleat:kiseonik 11S-oksidoreduktaza.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

linoleat + O₂

\rightleftharpoons

(9Z,12Z)-(11S)-11-hidroperoksioktadeka-9,12-dienoat

Produkt (9Z,12Z)-(11S)-11-hidroperoksioktadeka-9,12-dienoat, se konvertuje u (9Z,11E)-(13R)-13-hidroperoksioktadeka-9,11-dienoat.

Reference

^ Hamberg, M., Su, C. and Oliw, E.H. (1998). „Manganese lipoxygenase: Discovery of bis-allylic hydroperoxide as product and intermediate in a lipoxygenase reaction”. J. Biol. Chem. 273: 13080—13088. PMID 9582346.
^ Oliw, E.H., Su, C., Skogstrom, T. and Benthin, G. (1998). „Analysis of novel hydroperoxides and other metabolites of oleic, linoleic and linolenic acids by liquid chromatography-mass spectrometry with ion trap MSn”. Lipids. 33: 843—852. PMID 9778131.
^ Su, C. & Oliw, E.H. (1998). „Manganese lipoxygenase: Purification and characterization”. J. Biol. Chem. 273: 13072—13079. PMID 9582345.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Linoleate+11-lipoxygenase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Hamberg, M., Su, C. and Oliw, E.H. (1998). „Manganese lipoxygenase: Discovery of bis-allylic hydroperoxide as product and intermediate in a lipoxygenase reaction”. J. Biol. Chem. 273: 13080—13088. PMID 9582346.

[2] Oliw, E.H., Su, C., Skogstrom, T. and Benthin, G. (1998). „Analysis of novel hydroperoxides and other metabolites of oleic, linoleic and linolenic acids by liquid chromatography-mass spectrometry with ion trap MSn”. Lipids. 33: 843—852. PMID 9778131.

[3] Su, C. & Oliw, E.H. (1998). „Manganese lipoxygenase: Purification and characterization”. J. Biol. Chem. 273: 13072—13079. PMID 9582345.

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