PROFILPELAJAR.COM

Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Himaza
Himaza
Identifikatori
EC broj	3.4.21.39
CAS broj	97501-92-3
Baze podataka
IntEnz	IntEnz pregled
BRENDA	BRENDA pristup
ExPASy	NiceZyme pregled
KEGG	KEGG pristup
MetaCyc	metabolički put
PRIAM	profil
Strukture PBP	RCSB PDB PDBe PDBj PDBsum
PMC
Pretraga
PMC	članci
PubMed	članci
NCBI	proteini

Himaza (EC 3.4.21.39, skeletalna mišićna proteaza, kožna himotriptička proteinaza, mastocitna serinska proteinaza, himaza, skeletalna mišićna (SK) proteaza) je enzim.^[1]^[2]^[3] Ovaj enzim katalizuje sledeću hemijsku reakciju

Preferentno odvajanje: Phe- > Tyr- > Trp- > Leu-

Ovaj enzim je izolovan iz mastocitnih granulea.

Reference

^ Woodbury, R.G., Everitt, M. and Neurath, H. (1981). „Mast cell proteases”. Methods Enzymol. 80: 588—609. PMID 7043202.
^ Powers, J.C., Tanaka, T., Harper, J.W., Minematsu, Y., Barker, L., Lincoln, D., Crumley, K.V., Fraki, J.E., Schechter, N.M., Lazarus, G.G., Nakajima, K., Nakashino, K., Neurath, H. and Woodbury, R.G. (1985). „Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors”. Biochemistry. 24: 2048—2058. PMID 3893542.
^ Johnson, L.A., Moon, K.E. and Eisenberg, M. (1986). „Purification to homogeneity of the human skin chymotryptic proteinase "chymase"”. Anal. Biochem. 155: 358—364. PMID 2425663.

Literatura

Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.

Spoljašnje veze

Chymase на US National Library of Medicine Medical Subject Headings (MeSH)

[1] Woodbury, R.G., Everitt, M. and Neurath, H. (1981). „Mast cell proteases”. Methods Enzymol. 80: 588—609. PMID 7043202.

[2] Powers, J.C., Tanaka, T., Harper, J.W., Minematsu, Y., Barker, L., Lincoln, D., Crumley, K.V., Fraki, J.E., Schechter, N.M., Lazarus, G.G., Nakajima, K., Nakashino, K., Neurath, H. and Woodbury, R.G. (1985). „Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors”. Biochemistry. 24: 2048—2058. PMID 3893542.

[3] Johnson, L.A., Moon, K.E. and Eisenberg, M. (1986). „Purification to homogeneity of the human skin chymotryptic proteinase "chymase"”. Anal. Biochem. 155: 358—364. PMID 2425663.

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