Desmetilklozapin

Desmetilklozapin
Klinički podaci
Drugs.comMonografija
Identifikatori
CAS broj6104-71-8 ДаY
ATC kodnone
PubChemCID 2820
ChemSpider14126465 ДаY
UNII1I9001LWY8 ДаY
ChEMBLCHEMBL845 ДаY
Hemijski podaci
FormulaC17H17ClN4
Molarna masa312,797
  • Clc1ccc2Nc3ccccc3C(=Nc2c1)N4CCNCC4
  • InChI=1S/C17H17ClN4/c18-12-5-6-15-16(11-12)21-17(22-9-7-19-8-10-22)13-3-1-2-4-14(13)20-15/h1-6,11,19-20H,7-10H2 ДаY
  • Key:JNNOSTQEZICQQP-UHFFFAOYSA-N ДаY

Desmetilklozapin je organsko jedinjenje, koje sadrži 17 atoma ugljenika i ima molekulsku masu od 312,797 Da.

Osobine

Osobina Vrednost
Broj akceptora vodonika 4
Broj donora vodonika 2
Broj rotacionih veza 1
Particioni koeficijent[1] (ALogP) 2,9
Rastvorljivost[2] (logS, log(mol/L)) -4,3
Polarna površina[3] (PSA, Å2) 39,7

Reference

  1. ^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o. 
  2. ^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t. 
  3. ^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e. 

Literatura

Spoljašnje veze

Desmetilklozapin на Викимедијиној остави.

Read other articles:

Penataan ulang Demjanov

Artikel ini sebatang kara, artinya tidak ada artikel lain yang memiliki pranala balik ke halaman ini.Bantulah menambah pranala ke artikel ini dari artikel yang berhubungan atau coba peralatan pencari pranala.Tag ini diberikan pada Februari 2023. Penataan ulang Demjanov (berasal dari nama penemunya Nikolai Demyanov) adalah reaksi kimia amina primer dengan asam nitrat, menghasilkan alkohol yang tertata ulang.[1][2][3] Baik kontraksi maupun pembesaran cincin dapat terjadi. The Demjanov rearrange...

 

Heavy metal

Halaman ini berisi artikel tentang genre. Untuk subgenre, lihat genre heavy metal. Untuk album Newsted (2013), lihat Heavy Metal Music. Untuk kegunaan lain, lihat Heavy metal (disambiguasi).Heavy metalJudas Priest di Wacken Open Air 2018Nama lainMetalSumber aliranBlues rockrok psikedelisacid rockSumber kebudayaanAkhir 1960-an di Britania Raya dan Amerika SerikatBentuk turunanGrunge[1]Subgenre Avant-garde metal metal kristen metal ekstrim black metal death metal doom metal thrash metal...

 

National Register of Historic Places listings in Powhatan County, Virginia

Location of Powhatan County in Virginia This is a list of the National Register of Historic Places listings in Powhatan County, Virginia. This is intended to be a complete list of the properties and districts on the National Register of Historic Places in Powhatan County, Virginia, United States. The locations of National Register properties and districts for which the latitude and longitude coordinates are included below, may be seen in an online map.[1] There are 20 properties and ...

Veikkausliiga 2012

Veikkausliiga 2012 Competizione Veikkausliiga Sport Calcio Edizione 103ª Organizzatore SPL/FBF Date dal 15 aprile 2012al 27 ottobre 2012 Luogo  Finlandia Partecipanti 12 Formula Girone all'italiana Risultati Vincitore HJK(25º titolo) Retrocessioni Haka Statistiche Miglior marcatore Irakli Sirbiladze (17) Incontri disputati 198 Gol segnati 535 (2,7 per incontro) Cronologia della competizione 2011 2013 Manuale Haka HJK Honka Inter TurkuTPS Jaro JJK KuPS Lahti Mariehamn...

 

Pertusio

Cet article est une ébauche concernant une localité italienne et le Piémont. Vous pouvez partager vos connaissances en l’améliorant (comment ?) selon les recommandations des projets correspondants. Pertusio Noms Nom français Pertus Nom piémontais Përtus Administration Pays Italie Région Piémont  Ville métropolitaine Turin  Code postal 10080 Code ISTAT 001187 Préfixe tel. 0124 Démographie Population 772 hab. (31-12-2010[1]) Densité 193 hab./km2 Géograp...

 

Lahaul and Spiti Assembly constituency

Legislative Assembly constituency in Himachal Pradesh State, India Lahaul and SpitiConstituency No. 21 for the Himachal Pradesh Legislative AssemblyConstituency detailsCountryIndiaRegionNorth IndiaStateHimachal PradeshDistrictLahaul and SpitiLS constituencyMandiEstablished1967Total electors25,496[2]ReservationSTMember of Legislative Assembly14th Himachal Pradesh Legislative AssemblyIncumbent Vacant[1] PartyTBAElected yearTBA Lahaul and Spiti Assembly constituency is one of the...

Osman II

Questa voce o sezione sull'argomento sovrani non cita le fonti necessarie o quelle presenti sono insufficienti. Puoi migliorare questa voce aggiungendo citazioni da fonti attendibili secondo le linee guida sull'uso delle fonti. Segui i suggerimenti del progetto di riferimento. Osman IISultano dell'Impero ottomanoIn carica26 febbraio 1618 –20 maggio 1622 PredecessoreMustafa I SuccessoreMustafa I TrattamentoPadiscià Altri titoliCaliffo dell'IslamAmir al-Mu'mininCustode delle...

 

Masthead Island

Protected area in Queensland, AustraliaMasthead IslandQueenslandIUCN category II (national park) Masthead Island shorelineMasthead IslandNearest town or cityGladstoneCoordinates23°32′20″S 151°43′36″E / 23.53889°S 151.72667°E / -23.53889; 151.72667Area50 ha (124 acres)[1]Managing authoritiesQueensland Parks and Wildlife ServiceWebsiteMasthead IslandSee alsoProtected areas of Queensland Masthead Island is a coral cay located in the southern Grea...

 

哈萨克斯坦总统

此条目序言章节没有充分总结全文内容要点。 (2019年3月21日)请考虑扩充序言，清晰概述条目所有重點。请在条目的讨论页讨论此问题。 哈萨克斯坦總統哈薩克總統旗現任Қасым-Жомарт Кемелұлы Тоқаев卡瑟姆若马尔特·托卡耶夫自2019年3月20日在任任期7年首任努尔苏丹·纳扎尔巴耶夫设立1990年4月24日（哈薩克蘇維埃社會主義共和國總統） 哈萨克斯坦 哈萨克斯坦政府...

NGC 3613

NGC 3613   الكوكبة الدب الأكبر[1]  رمز الفهرس NGC 3613 (الفهرس العام الجديد)MCG+10-16-109 (فهرس المجرات الموروفولوجي)PGC 34583 (فهرس المجرات الرئيسية)UGC 6323 (فهرس أوبسالا العام)2MASX J11183613+5759597 (Two Micron All-Sky Survey, Extended source catalogue)SDSS J111836.10+575959.9 (مسح سلووان الرقمي للسماء)Z 291-49 (فهرس المجرات وعناقيد...

 

Moon Sung-kil

Artikel ini perlu diwikifikasi agar memenuhi standar kualitas Wikipedia. Anda dapat memberikan bantuan berupa penambahan pranala dalam, atau dengan merapikan tata letak dari artikel ini. Untuk keterangan lebih lanjut, klik [tampil] di bagian kanan. Mengganti markah HTML dengan markah wiki bila dimungkinkan. Tambahkan pranala wiki. Bila dirasa perlu, buatlah pautan ke artikel wiki lainnya dengan cara menambahkan [[ dan ]] pada kata yang bersangkutan (lihat WP:LINK untuk keterangan lebih lanjut...

 

Cross of Burgundy

Historical banner and battle flag Cross of Burgundy The Cross of Burgundy (French: Croix de Bourgogne; Spanish: Cruz de Borgoña/Aspa de Borgoña; German: Burgunderkreuz; Italian: Croce di Borgogna; Catalan: Creu de Borgonya; Dutch: Bourgondisch kruis; Portuguese: Cruz de Borgonha) is a saw-toothed (raguly) form of the Cross of Saint Andrew, the patron saint of Burgundy, and a historical banner and battle flag used by holders of the title of Duke of Burgundy and their subjects. It was first u...

Kejuaraan Dunia BWF 2015

Kejuaraan Dunia BWF 2015Informasi turnamenEdisike-ke-22LevelInternasionalTempatpenyelenggaraanIstora Gelora Bung Karno (Istora Senayan)Jakarta ← Kopenhagen 2014 Glasgow 2017 → Kejuaraan Dunia BWF 2015 merupakan edisi ke-22 dari Kejuaraan Dunia BWF yang diadakan oleh Federasi Bulu Tangkis Dunia akan diselenggarakan pada 10-16 Agustus 2015 di Istora Gelora Bung Karno, Jakarta, Indonesia.[1] Undian Undian dilaksanakan pada 28 Juli 2015 pukul 11:00 Waktu Indonesia Barat di Museum Bank...

 

Spirituality

Philosophical and theological term For the belief in being able to contact the dead, see Spiritualism (beliefs). Part of a series onSpirituality Outline Religion History Timeline Traditional Elite religion Jewish Merkabah Kabbalah Hasidism Christian Catholic Mysticism Sufism Folk religion Modern Buddhist modernism New religious movement Secular spirituality Spiritual but not religious Syncretism Spiritual experience Lived religion Mystical experience Oceanic feeling Religious experience Relig...

 

Shadyside Presbyterian Church

Historic church in Pennsylvania, United States United States historic placeShadyside Presbyterian ChurchU.S. National Register of Historic PlacesPittsburgh Landmark – PHLF Shadyside Presbyterian ChurchShow map of PittsburghShow map of PennsylvaniaShow map of the United StatesLocationAmberson Ave. and Westminster Pl., Pittsburgh, PennsylvaniaCoordinates40°26′57″N 79°56′21″W / 40.44917°N 79.93917°W / 40.44917; -79.93917Built1889ArchitectShepley, Rutan &...

Tsardom of Russia

1547–1721 Russian state Tsardom of RussiaРусское царствоRusskoye tsarstvo1547–1721 Flag(1693–1721) Coat of arms(1667–1721) Seal of Tsar Ivan IV (c. 1539):Territory of Russia in     1500      1600 and      1700CapitalMoscow(1547–1712)Saint Petersburg(1712–1721)Common languagesRussian (official)Religion Russian Orthodox (official)[1]Demonym(s)RussianGovernmentAbsolute monarchyTsar&#...

 

Coach Ernie Pantusso

Fictional character in the series Cheers Fictional character Ernie Coach PantussoCoach ruins the blender by mixing a recipe with the coconut cup in Cliff's Rocky Moment (episode 38, 1984)First appearanceGive Me a Ring Sometime (episode 1.01)Last appearanceRescue Me (episode 3.25)Portrayed byNicholas ColasantoIn-universe informationOccupationBaseball coach (retired)Assistant bartender (1982–1985) (until death)FamilyTwo unnamed brothersUnnamed sisterSpouseAngela (deceased)ChildrenLisa Pantuss...

 

العلاقات الأرمنية القبرصية

العلاقات الأرمينية القبرصية أرمينيا قبرص   أرمينيا   قبرص تعديل مصدري - تعديل   العلاقات الأرمينية القبرصية هي العلاقات الثنائية التي تجمع بين أرمينيا وقبرص.[1][2][3][4][5] مقارنة بين البلدين هذه مقارنة عامة ومرجعية للدولتين: وجه المقارنة أرمي�...

The Little Matchgirl (2006 film)

2006 short film by Roger Allers The Little MatchgirlDirected byRoger AllersScreenplay byRoger AllersKevin L. HarkeyEd GombertMark WaltonRalph ZondagBased onThe Little Match Girlby Hans Christian AndersenProduced byDon HahnBaker BloodworthEdited byJessica Ambinder RojasProductioncompaniesWalt Disney Animation Studios[a]Walt Disney PicturesDistributed byBuena Vista Pictures DistributionRelease date July 7, 2006 (2006-07-07) Running time7 minutesCountryUnited States The Li...

 

Michael S. Regan

Michael S. Regan Administrator Badan Perlindungan Lingkungan Hidup ke-16PetahanaMulai menjabat 11 Maret 2021PresidenJoe BidenWakilJanet McCabe (nominee)PendahuluAndrew R. WheelerPenggantiPetahanaSekretaris Departemen Kualitas Lingkungan Hidup Carolina Utara ke-2Masa jabatan3 Januari 2017 – 11 Maret 2021GubernurRoy CooperPendahuluDonald van der VaartPenggantiDionne Delli-Gatti Informasi pribadiLahir6 Agustus 1976 (umur 48)[1]Goldsboro, Carolina Utara, Amerika Serika...